Ludmil B. Alexandrov
Title
Cited by
Cited by
Year
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
56882013
Mutational Processes Molding the Genomes of 21 Breast Cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
13652012
The Life History of 21 Breast Cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
11292012
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
10592016
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
8622015
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353–357, 2015
8622015
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ...
Nature Genetics 47 (5), 505–511, 2015
8212015
Deciphering Signatures of Mutational Processes Operative in Human Cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton
Cell Reports 3 (1), 246-259, 2013
7092013
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature Communications 5 (2997), 2014
6102014
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ...
Nature Medicine 21 (7), 751-759, 2015
5072015
Mutational signatures associated with tobacco smoking in human cancer
LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ...
Science 354 (6312), 618-622, 2016
4712016
Whole-genome landscapes of major melanoma subtypes
NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ...
Nature 545, 175–180, 2017
4682017
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature Genetics 47 (12), 1402–1407, 2015
4542015
Timing, rates and spectra of human germline mutation
R Rahbari, A Wuster, SJ Lindsay, RJ Hardwick, LB Alexandrov, S Al Turki, ...
Nature Genetics 48, 126–133, 2016
4362016
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
LB Alexandrov, MR Stratton
Current Opinion in Genetics & Development 24, 52-60, 2014
3262014
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ...
Nature Genetics 47 (4), 367-372, 2015
3122015
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538, 378–382, 2016
2842016
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ...
Science 345 (6196), 1251343, 2014
2652014
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
E Papaemmanuil, I Rapado, Y Li, NE Potter, DC Wedge, J Tubio, ...
Nature Genetics 46 (2), 116–125, 2014
2622014
Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer
EP Murchison, OB Schulz-Trieglaff, Z Ning, LB Alexandrov, MJ Bauer, ...
Cell 148 (4), 780-791, 2012
2612012
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Articles 1–20