Targeting C-reactive protein for the treatment of cardiovascular disease MB Pepys, GM Hirschfield, GA Tennent, J Ruth Gallimore, MC Kahan, ... Nature 440 (7088), 1217-1221, 2006 | 912 | 2006 |
Organic synthesis: march of the machines SV Ley, DE Fitzpatrick, RJ Ingham, RM Myers Angewandte Chemie International Edition 54 (11), 3449-3464, 2015 | 515 | 2015 |
Machine‐assisted organic synthesis SV Ley, DE Fitzpatrick, RM Myers, C Battilocchio, RJ Ingham Angewandte Chemie International Edition 54 (35), 10122-10136, 2015 | 238 | 2015 |
Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes CA Watts, FM Richards, A Bender, PJ Bond, O Korb, O Kern, M Riddick, ... Chemistry & biology 20 (11), 1399-1410, 2013 | 185 | 2013 |
Flow chemistry meets advanced functional materials RM Myers, DE Fitzpatrick, RM Turner, SV Ley Chemistry–A European Journal 20 (39), 12348-12366, 2014 | 134 | 2014 |
Science of Synthesis: Houben-Weyl Methods of Molecular Transformations J Backes Thieme, 2008 | 109* | 2008 |
Cancer, chemistry, and the cell: molecules that interact with the neurotensin receptors RM Myers, JW Shearman, MO Kitching, A Ramos-Montoya, DE Neal, ... ACS chemical biology 4 (7), 503-525, 2009 | 96 | 2009 |
Synthesis of the thapsigargins SV Ley, A Antonello, EP Balskus, DT Booth, SB Christensen, E Cleator, ... Proceedings of the National Academy of Sciences 101 (33), 12073-12078, 2004 | 92 | 2004 |
Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins X Qi, F Loiseau, WL Chan, Y Yan, Z Wei, LG Milroy, RM Myers, SV Ley, ... Journal of Biological Chemistry 286 (18), 16163-16173, 2011 | 64 | 2011 |
Organische Synthese: Vormarsch der Maschinen SV Ley, DE Fitzpatrick, RJ Ingham, RM Myers Angewandte Chemie 127 (11), 3514-3530, 2015 | 58 | 2015 |
A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles TM Beale, DM Allwood, A Bender, PJ Bond, JD Brenton, ... ACS medicinal chemistry letters 3 (3), 177-181, 2012 | 55 | 2012 |
Reductive Cleavage of N− O Bonds Using Samarium (II) Iodide in a Traceless Release Strategy for Solid-Phase Synthesis RM Myers, SP Langston, SP Conway, C Abell Organic Letters 2 (10), 1349-1352, 2000 | 47 | 2000 |
Chiral glycolate equivalents for the asymmetric synthesis of α-hydroxycarbonyl compounds SV Ley, TD Sheppard, RM Myers, MS Chorghade Bulletin of the Chemical Society of Japan 80 (8), 1451-1472, 2007 | 43 | 2007 |
In vitro mutagenesis and overexpression of the Escherichia coli trpA gene and the partial characterization of the resultant tryptophan synthase mutant alpha-subunits. DL Milton, ML Napier, RM Myers, JK Hardman Journal of Biological Chemistry 261 (35), 16604-16615, 1986 | 41 | 1986 |
Total syntheses of subereamollines A and B JW Shearman, RM Myers, JD Brenton, SV Ley Organic & Biomolecular Chemistry 9 (1), 62-65, 2011 | 38 | 2011 |
Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A–1 TM Beale, PJ Bond, JD Brenton, DS Charnock-Jones, SV Ley, RM Myers Bioorganic & medicinal chemistry 20 (5), 1749-1759, 2012 | 33 | 2012 |
Antivascular and anticancer activity of dihalogenated A-ring analogues of combretastatin A-4 TM Beale, RM Myers, JW Shearman, DS Charnock-Jones, JD Brenton, ... MedChemComm 1 (3), 202-208, 2010 | 33 | 2010 |
Maschinengestützte organische Synthese SV Ley, DE Fitzpatrick, RM Myers, C Battilocchio, RJ Ingham Angewandte Chemie 127 (35), 10260-10275, 2015 | 27 | 2015 |
Automated electrochemical selenenylations N Amri, T Wirth Synthesis 52 (12), 1751-1761, 2020 | 25 | 2020 |
Spiroketals SV Ley, LG Milroy, RM Myers ChemInform 40 (15), no-no, 2009 | 24 | 2009 |