Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster I Bjedov, JM Toivonen, F Kerr, C Slack, J Jacobson, A Foley, L Partridge Cell metabolism 11 (1), 35-46, 2010 | 1207 | 2010 |
dFOXO‐independent effects of reduced insulin‐like signaling in Drosophila C Slack, ME Giannakou, A Foley, M Goss, L Partridge Aging cell 10 (5), 735-748, 2011 | 232 | 2011 |
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs S Broughton, N Alic, C Slack, T Bass, T Ikeya, G Vinti, AM Tommasi, ... PloS one 3 (11), e3721, 2008 | 226 | 2008 |
The Ras-Erk-ETS-signaling pathway is a drug target for longevity C Slack, N Alic, A Foley, M Cabecinha, MP Hoddinott, L Partridge Cell 162 (1), 72-83, 2015 | 207 | 2015 |
Activation of AMPK by the Putative Dietary Restriction Mimetic Metformin Is Insufficient to Extend Lifespan in Drosophila C Slack, A Foley, L Partridge Public Library of Science 7 (10), e47699, 2012 | 197 | 2012 |
Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 180 | 2016 |
DILP‐producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition SJ Broughton, C Slack, N Alic, A Metaxakis, TM Bass, Y Driege, ... Aging cell 9 (3), 336-346, 2010 | 142 | 2010 |
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ... Molecular systems biology 7 (1), 502, 2011 | 141 | 2011 |
Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk C Slack, C Werz, D Wieser, N Alic, A Foley, H Stocker, DJ Withers, ... PLoS Genetics 6 (3), e1000881, 2010 | 109 | 2010 |
Insulin signalling regulates remating in female Drosophila S Wigby, C Slack, S Grönke, P Martinez, FCF Calboli, T Chapman, ... Proceedings of the Royal Society B: Biological Sciences 278 (1704), 424-431, 2011 | 73 | 2011 |
Cell-nonautonomous effects of dFOXO/DAF-16 in aging N Alic, JM Tullet, T Niccoli, S Broughton, MP Hoddinott, C Slack, D Gems, ... Cell reports 6 (4), 608-616, 2014 | 63 | 2014 |
Expression and purification of recombinant G protein-coupled receptors: A review DN Wiseman, A Otchere, JH Patel, R Uddin, NL Pollock, SJ Routledge, ... Protein Expression and Purification 167, 105524, 2020 | 54 | 2020 |
To help aging populations, classify organismal senescence SRG Calimport, BL Bentley, CE Stewart, G Pawelec, A Scuteri, ... Science 366 (6465), 576-578, 2019 | 52 | 2019 |
Ras signaling in aging and metabolic regulation C Slack Nutrition and healthy aging 4 (3), 195-205, 2017 | 48 | 2017 |
Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome C Slack, PM Overton, RI Tuxworth, W Chia Oxford University Press for The Company of Biologists Limited 134 (21), 3781 …, 2007 | 47 | 2007 |
Detrimental Effects of RNAi: A Cautionary Note on Its Use in Drosophila Ageing Studies N Alic, MP Hoddinott, A Foley, C Slack, MDW Piper, L Partridge Public Library of Science 7 (9), e45367, 2012 | 39 | 2012 |
A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions C Slack, WG Somers, R Sousa-Nunes, W Chia, PM Overton BMC genetics 7, 1-16, 2006 | 26 | 2006 |
Rearrangement of extracellular matrix during cluster formation by human luteinising granulosa cells in culture MC Richardson, C Slack, IJ Stewart The Journal of Anatomy 196 (2), 243-248, 2000 | 22 | 2000 |
Zoledronate extends health span and survival via the mevalonate pathway in a FOXO-dependent manner Z Chen, J Cordero, AM Alqarni, C Slack, MP Zeidler, I Bellantuono The Journals of Gerontology: Series A 77 (8), 1494-1502, 2022 | 12 | 2022 |
Signal transduction pathways in ageing C Slack, J Tullet Biochemistry and Cell Biology of Ageing: Part I Biomedical Science, 323-350, 2018 | 8 | 2018 |