| A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013 | 1175 | 2013 |
| A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ... Nature biotechnology 26 (10), 1155-1160, 2008 | 678 | 2008 |
| An assessment of sustainable housing affordability using a multiple criteria decision making method E Mulliner, K Smallbone, V Maliene Omega 41 (2), 270-279, 2013 | 449 | 2013 |
| Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer RA Gatenby, K Smallbone, PK Maini, F Rose, J Averill, RB Nagle, ... British journal of cancer 97 (5), 646-653, 2007 | 439 | 2007 |
| Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 309 | 2016 |
| Metabolic changes during carcinogenesis: potential impact on invasiveness K Smallbone, RA Gatenby, RJ Gillies, PK Maini, DJ Gavaghan Journal of theoretical biology 244 (4), 703-713, 2007 | 245 | 2007 |
| SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 203 | 2020 |
| The role of acidity in solid tumour growth and invasion K Smallbone, DJ Gavaghan, RA Gatenby, PK Maini Journal of theoretical biology 235 (4), 476-484, 2005 | 202 | 2005 |
| Towards a genome-scale kinetic model of cellular metabolism K Smallbone, E Simeonidis, N Swainston, P Mendes BMC systems biology 4 (1), 6, 2010 | 198 | 2010 |
| Yeast 5 – an expanded reconstruction of the Saccharomyces cerevisiae metabolic network BD Heavner, K Smallbone, B Barker, P Mendes, LP Walker BMC Systems Biology 6, 55, 2012 | 182 | 2012 |
| Improving metabolic flux predictions using absolute gene expression data K Smallbone, D Lee, WB Dunn, E Murabito, CL Winder, DB Kell, ... BMC Systems Biology 6, 73, 2012 | 180* | 2012 |
| A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes K Smallbone, HL Messiha, KM Carroll, CL Winder, N Malys, WB Dunn, ... FEBS letters 587 (17), 2832-2841, 2013 | 159 | 2013 |
| Systematic construction of kinetic models from genome-scale metabolic networks NJ Stanford, T Lubitz, K Smallbone, E Klipp, P Mendes, W Liebermeister PloS one 8 (11), e79195, 2013 | 141 | 2013 |
| Further developments towards a genome-scale metabolic model of yeast K Smallbone, P Dobson, D Jameson, E Simeonidis, K Lanthaler, P Pir, ... BMC Systems Biology 4, 145, 2010 | 140* | 2010 |
| The SuBliMinaL toolbox: automating steps in the reconstruction of metabolic networks N Swainston, K Smallbone, P Mendes, D Kell, N Paton Journal of Integrative Bioinformatics 8 (2), 186, 2011 | 126 | 2011 |
| Version 6 of the consensus yeast metabolic network refines biochemical coverage and improves model performance BD Heavner, K Smallbone, ND Price, LP Walker Database 2013, bat059, 2013 | 124 | 2013 |
| Something from nothing − bridging the gap between constraint‐based and kinetic modelling K Smallbone, E Simeonidis, DS Broomhead, DB Kell FEBS Journal 274 (21), 5576-5585, 2007 | 124 | 2007 |
| Metabolic regulation is sufficient for global and robust coordination of glucose uptake, catabolism, energy production and growth in Escherichia coli P Millard, K Smallbone, P Mendes PLoS computational biology 13 (2), e1005396, 2017 | 115 | 2017 |
| Flux balance analysis: A geometric perspective K Smallbone, E Simeonidis Journal of theoretical biology 258 (2), 311-315, 2009 | 95 | 2009 |
| BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology AF Villaverde, D Henriques, K Smallbone, S Bongard, J Schmid, ... BMC systems biology 9, 1-15, 2015 | 93 | 2015 |
| Large-scale metabolic models: From reconstruction to differential equations K Smallbone, P Mendes Industrial Biotechnology 9 (4), 179-184, 2013 | 77 | 2013 |
| Why are (the best) women so good at chess? Participation rates and gender differences in intellectual domains M Bilalić, K Smallbone, P McLeod, F Gobet Proceedings of the Royal Society B: Biological Sciences 276 (1659), 1161, 2009 | 73 | 2009 |
| Toward community standards and software for whole-cell modeling D Waltemath, JR Karr, FT Bergmann, V Chelliah, M Hucka, M Krantz, ... IEEE Transactions on Biomedical Engineering 63 (10), 2007-2014, 2016 | 64 | 2016 |
| Capturing the essence of a metabolic network: a flux balance analysis approach E Murabito, E Simeonidis, K Smallbone, J Swinton Journal of theoretical biology 260 (3), 445-452, 2009 | 55 | 2009 |
| A probabilistic approach to identify putative drug targets in biochemical networks E Murabito, K Smallbone, J Swinton, HV Westerhoff, R Steuer Journal of The Royal Society Interface 8 (59), 880-895, 2011 | 52 | 2011 |
| Mathematical modelling of tumour acidity K Smallbone, RA Gatenby, PK Maini Journal of theoretical biology 255 (1), 106-112, 2008 | 47 | 2008 |
| Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism O Davies, P Mendes, K Smallbone, N Malys BMB Reports 45 (4), 295-264, 2012 | 37 | 2012 |
| Why does yeast ferment? A flux balance analysis study E Simeonidis, E Murabito, K Smallbone, HV Westerhoff Biochemical Society Transactions 38 (5), 1225-1229, 2010 | 35 | 2010 |
| Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity K Smallbone, PK Maini, RA Gatenby Biology Direct 5 (22), 2010 | 33 | 2010 |
| Enzyme kinetics informatics: from instrument to browser N Swainston, M Golebiewski, HL Messiha, N Malys, R Kania, S Kengne, ... FEBS Journal 277 (18), 3769-3779, 2010 | 31 | 2010 |
| Playing off the curve-testing quantitative predictions of skill acquisition theories in development of chess performance R Gaschler, J Progscha, K Smallbone, N Ram, M Bilalić Frontiers in psychology 5, 103676, 2014 | 29 | 2014 |
| Bicarbonate‐rich fluid secretion predicted by a computational model of guinea‐pig pancreatic duct epithelium M Yamaguchi, MC Steward, K Smallbone, Y Sohma, A Yamamoto, ... The Journal of Physiology 595 (6), 1947-1972, 2017 | 27 | 2017 |
| A robust and efficient method for estimating enzyme complex abundance and metabolic flux from expression data BE Barker, N Sadagopan, Y Wang, K Smallbone, CR Myers, H Xi, ... Computational biology and chemistry 59, 98-112, 2015 | 25 | 2015 |
| Building a kinetic model of trehalose biosynthesis in Saccharomyces cerevisiae. K Smallbone, N Malys, HL Messiha, JA Wishart, E Simeonidis Methods in Enzymology: Methods in Systems Biology 500, 355, 2011 | 24 | 2011 |
| Tumour glycolysis: the many faces of HIF C Kelly, K Smallbone, JM Brady Journal of theoretical biology 254 (2), 508-513, 2008 | 24 | 2008 |
| Enzyme characterisation and kinetic modelling of the pentose phosphate pathway in yeast HL Messiha, E Kent, N Malys, KM Carroll, N Swainston, P Mendes, ... PeerJ PrePrints, 2014 | 20 | 2014 |
| A mathematical model of the colon crypt capturing compositional dynamic interactions between cell types K Smallbone, BM Corfe International journal of experimental pathology 95 (1), 1-7, 2014 | 19 | 2014 |
| Striking a balance with Recon 2.1 K Smallbone arXiv preprint arXiv:1311.5696, 2013 | 15 | 2013 |
| Modelling acidosis and the cell cycle in multicellular tumour spheroids MJ Tindall, L Dyson, K Smallbone, PK Maini Journal of Theoretical Biology 298, 107-115, 2012 | 13 | 2012 |
| Quiescence as a mechanism for cyclical hypoxia and acidosis K Smallbone, DJ Gavaghan, PK Maini, JM Brady Journal of mathematical biology 55 (5), 767-779, 2007 | 11 | 2007 |
| Computational Methods in Systems Biology P Mendes, JO Dada, K Smallbone Springer, 2014 | 8* | 2014 |
| Kinetic modelling of metabolic pathways: application to serine biosynthesis K Smallbone, NJ Stanford Systems Metabolic Engineering : Methods and Protocols 985, 113-121, 2013 | 5 | 2013 |
| Kinetic modelling of large-scale metabolic networks P Mendes, NJ Stanford, K Smallbone Proceedings of the 9th International Conference on Computational Methods in …, 2011 | 4 | 2011 |
| Modelling aspects of tumour metabolism PK Maini, RA Gatenby, K Smallbone International Congress of Mathematicians, 2010 | 4 | 2010 |
| Multi-scale modelling of E. coli metabolism P Millard, K Smallbone PeerJ 3, e1128, 2015 | 3 | 2015 |
| Metabolic Control Analysis: Rereading Reder K Smallbone arXiv preprint arXiv:1305.6449, 2013 | 2 | 2013 |
| Standardized network reconstruction of E. coli metabolism K Smallbone arXiv preprint arXiv:1304.2960, 2013 | 2 | 2013 |
| A model to investigate the feasibility of FDG as a surrogate marker of hypoxia CJ Kelly, K Smallbone, T Roose, JM Brady Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE …, 2007 | 2 | 2007 |
| Size dependent growth in metabolic networks H Dorrian, J Borresen, K Smallbone arXiv preprint arXiv:1210.2550, 2012 | 1 | 2012 |
| Kinetic modelling of metabolic pathways NJ Stanford, K Smallbone The Bioinformatics Knowledgeblog, 2011 | 1 | 2011 |
| Constraint-based optimisation tools for semi-automated refinement of genome-scale yeast metabolic models P Pir, PD Dobson, K Smallbone, P Mendes, RD King, C Lu, SG Oliver, ... | 1 | 2010 |
| The role of acidity in tumour development K Smallbone | 1 | 2007 |
| Mathematising biology K Smallbone, Y Wang Manchester Institute for Mathematical Sciences, University of Manchester, 2015 | | 2015 |
| BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology JR Banga, J Jaeger, P Mendes, E Balsa-Canto, K Mauch, ... | | 2015 |
| BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology–Supplementary Information AF Villaverde, D Henriques, K Smallbone, S Bongard, J Schmid, ... | | 2014 |
| Modelling of metabolic control by Short Chain Fatty Acids at the level of the functional proteome–II: systems biology model of SCFA metabolism BM Corfe, CA Evans, E Murabito, K Smallbone Proceedings of the Nutrition Society 72 (OCE4), E236, 2013 | | 2013 |
| Mechanistic modelling of cancer: some reflections from software engineering and philosophy of science JM Cañete-Valdeón, R Wieringa, K Smallbone Naturwissenschaften 99, 973-983, 2012 | | 2012 |
| Why do Patients get Metachronous Colorectal Adenomas? JP Bury, S Riley, CA Evans, EA Williams, CA Staton, E Murabito, ... Journal of Pathology 228, S3, 2012 | | 2012 |
| Dave Broomhead's 60th Birthday M Muldoon, J Huke, K Smallbone Mathematics Today 47 (2), 68-69, 2011 | | 2011 |
| Research Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity K Smallbone, PK Maini, RA Gatenby | | 2010 |
| One lump or two? K Smallbone Nature Publishing Group, 2009 | | 2009 |
| Perfect numbers over simple algebraic number fields K Smallbone | | 2002 |
| Development of an extensible system for the capture and storage of experimental enzyme kinetics data N Swainston, K Smallbone, F Khan, I Spasic, M Golebiewski, I Rojas, ... | | |
| Towards the digital Escherichia coli P Millard, K Smallbone, M Manca, P Mendes | | |
Pedro MendesUniversity of ConnecticutVerified email at uchc.edu
