NPC1/NPC2 function as a tag team duo to mobilize cholesterol K Subramanian, WE Balch Proceedings of the National Academy of Sciences 105 (40), 15223-15224, 2008 | 122 | 2008 |
Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two‐step reaction mechanism H Hou, AT John Peter, C Meiringer, K Subramanian, C Ungermann Traffic 10 (8), 1061-1073, 2009 | 86 | 2009 |
Quantitative proteomics of human fibroblasts with I1061T mutation in Niemann–Pick C1 (NPC1) protein provides insights into the disease pathogenesis N Rauniyar, K Subramanian, M Lavallée-Adam, S Martínez-Bartolomé, ... Molecular & Cellular Proteomics 14 (7), 1734-1749, 2015 | 80 | 2015 |
Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells NH Pipalia, K Subramanian, S Mao, H Ralph, DM Hutt, SM Scott, ... Journal of lipid research 58 (4), 695-708, 2017 | 71 | 2017 |
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8 H Hou, K Subramanian, TJ LaGrassa, D Markgraf, LEP Dietrich, J Urban, ... Proceedings of the National Academy of Sciences 102 (48), 17366-17371, 2005 | 63 | 2005 |
Palmitoylation determines the function of Vac8 at the yeast vacuole K Subramanian, LEP Dietrich, H Hou, TJ LaGrassa, CTA Meiringer, ... Journal of cell science 119 (12), 2477-2485, 2006 | 62 | 2006 |
Quantitative analysis of the proteome response to the histone deacetylase inhibitor (HDACi) vorinostat in Niemann-Pick Type C1 disease K Subramanian, N Rauniyar, M Lavalleé-Adam, JR Yates III, WE Balch Molecular & Cellular Proteomics 16 (11), 1938-1957, 2017 | 35 | 2017 |
2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease J Davidson, E Molitor, S Moores, SE Gale, K Subramanian, X Jiang, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 28 | 2019 |
Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process C Wang, SM Scott, K Subramanian, S Loguercio, P Zhao, DM Hutt, ... Nature communications 10 (1), 5052, 2019 | 26 | 2019 |
Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid K Subramanian, DM Hutt, SM Scott, V Gupta, S Mao, WE Balch Journal of Biological Chemistry 295 (23), 8017-8035, 2020 | 23 | 2020 |
Compounding of glass fiber‐reinforced polypropylene and investigation of its mechanical properties under simple and complex loading SN Pandit, VB Gupta, K Subramanian Polymer Composites 2 (2), 68-74, 1981 | 20 | 1981 |
HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts NH Pipalia, SZ Saad, K Subramanian, A Cross, A Al-Motawa, K Garg, ... Journal of Lipid Research 62, 2021 | 13 | 2021 |
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid K Subramanian, DM Hutt, V Gupta, S Mao, WE Balch bioRxiv, 724187, 2019 | 3 | 2019 |
Quantitative analysis of the proteome response to histone deacetylase inhibitor in Niemann-pick type C1 disease K Subramanian, N Rauniyar, JR Yates, WE Balch Molecular Genetics and Metabolism 2 (117), S110, 2016 | | 2016 |
Quantitative proteomics of human NPC1 I1061T mutant fibroblasts provides insights into the pathogenesis of Niemann-Pick Type C disease N Rauniyar, K Subramanian, M Lavallee‐Adam Mol Cell Proteomics, 2015 | | 2015 |
Proteostatic rescue of a high fraction of human NPC1 mutations by HDAC inhibitors S Mao, N Pipalia, K Subramanian, W Balch, F Maxfield MOLECULAR BIOLOGY OF THE CELL 24, 2013 | | 2013 |
Testing the effect of drugs on arrays of NPC1 mutations. S Mao, N Pipalia, K Subramanian, W Balch, F Maxfield MOLECULAR BIOLOGY OF THE CELL 22, 2011 | | 2011 |
The Role of Protein Palmitoylation for Protein Function at the yeast vacuole K Subramanian | | 2007 |
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8 J Urban, N Decker, C Ungermann, H Hou, K Subramanian, TJ LaGrassa, ... | | |