| Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells A Hendel*, RO Bak*, JT Clark, AB Kennedy, DE Ryan, S Roy, I Steinfeld, ... Nature Biotechnology, 2015 | 1166 | 2015 |
| Activation of proto-oncogenes by disruption of chromosome neighborhoods D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ... Science, 2016 | 1035 | 2016 |
| CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells DP Dever*, RO Bak*, A Reinisch, J Camarena, G Washington, CE Nicolas, ... Nature, 2016 | 905 | 2016 |
| A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ... Nature medicine 24 (8), 1216-1224, 2018 | 730 | 2018 |
| IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication MR Jakobsen, RO Bak, A Andersen, RK Berg, SB Jensen, T Jin, ... PNAS, 2013 | 374 | 2013 |
| CRISPR/Cas9 genome editing in human hematopoietic stem cells RO Bak, DP Dever, MH Porteus Nature protocols 13 (2), 358-376, 2018 | 284 | 2018 |
| Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses CK Holm, SH Rahbek, HH Gad, RO Bak, MR Jakobsen, Z Jiang, ... Nature Communications, 2016 | 215 | 2016 |
| miRNA sponges: soaking up miRNAs for regulation of gene expression RO Bak, JG Mikkelsen Wiley Interdisciplinary Reviews (WIREs): RNA, 2014 | 205 | 2014 |
| Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 167 | 2019 |
| Gene editing on center stage RO Bak, N Gomez-Ospina, MH Porteus Trends in Genetics 34 (8), 600-611, 2018 | 167 | 2018 |
| Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes MN Primo, RO Bak, B Schibler, JG Mikkelsen Cytokine, 2012 | 127 | 2012 |
| CRISPR-mediated integration of large gene cassettes using AAV donor vectors RO Bak, MH Porteus Cell Reports, 2017 | 122 | 2017 |
| Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6 RO Bak, DP Dever, A Reinisch, DC Hernandez, R Majeti, MH Porteus eLife, 2017 | 120 | 2017 |
| Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ... Molecular Therapy 26 (10), 2431-2442, 2018 | 110 | 2018 |
| Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases Y Cai, RO Bak, JG Mikkelsen eLife, 2014 | 110 | 2014 |
| Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, ... Nature Communications 10, 4045, 2019 | 106 | 2019 |
| Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ... Science translational medicine 13 (598), eabf2444, 2021 | 100 | 2021 |
| STEEP mediates STING ER exit and activation of signaling B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ... Nature immunology 21 (8), 868-879, 2020 | 91 | 2020 |
| Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells B Moldt, C Miskey, NH Staunstrup, A Gogol-Döring, RO Bak, N Sharma, ... Molecular Therapy, 2011 | 90 | 2011 |
| Priming human repopulating hematopoietic stem and progenitor cells for Cas9/sgRNA gene targeting CT Charlesworth, J Camarena, MK Cromer, S Vaidyanathan, RO Bak, ... Molecular Therapy-Nucleic Acids 12, 89-104, 2018 | 89 | 2018 |
Daniel P. DeverStanford University Medical CenterVerified email at stanford.edu
