Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid SM Weldon, AC Mullen, CE Loscher, LA Hurley, HM Roche The Journal of nutritional biochemistry 18 (4), 250-258, 2007 | 409 | 2007 |
Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding CC Taggart, SA Cryan, S Weldon, A Gibbons, CM Greene, E Kelly, ... The Journal of experimental medicine 202 (12), 1659-1668, 2005 | 277 | 2005 |
Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation S Weldon, P McNally, NG McElvaney, JS Elborn, DF McAuley, J Wartelle, ... The Journal of Immunology 183 (12), 8148-8156, 2009 | 151 | 2009 |
The role of serine proteases and antiproteases in the cystic fibrosis lung MS Twigg, S Brockbank, P Lowry, SP FitzGerald, C Taggart, S Weldon Mediators of inflammation 2015, 2015 | 136 | 2015 |
Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo A Scott, S Weldon, PJ Buchanan, B Schock, RK Ernst, DF McAuley, ... PloS one 6 (10), e26525, 2011 | 122 | 2011 |
SLPI and elafin: multifunctional antiproteases of the WFDC family A Scott, S Weldon, CC Taggart Biochemical Society Transactions 39 (5), 1437-1440, 2011 | 122 | 2011 |
Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis N Guyot, MW Butler, P McNally, S Weldon, CM Greene, RL Levine, ... Journal of biological chemistry 283 (47), 32377-32385, 2008 | 112 | 2008 |
miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production S Weldon, P McNally, DF McAuley, IK Oglesby, CL Wohlford-Lenane, ... American journal of respiratory and critical care medicine 190 (2), 165-174, 2014 | 93 | 2014 |
Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice RF Foronjy, AJ Dabo, CC Taggart, S Weldon, P Geraghty PloS one 9 (2), e90567, 2014 | 82 | 2014 |
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma CA Butler, S McQuaid, CC Taggart, S Weldon, R Carter, G Skibinski, ... Thorax 67 (5), 392-398, 2012 | 80 | 2012 |
Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis S Zaric, C Shelburne, R Darveau, DJ Quinn, S Weldon, CC Taggart, ... Infection and immunity 78 (10), 4151-4156, 2010 | 73 | 2010 |
The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses S Weldon, N McGarry, CC Taggart, NG McElvaney Biochemical Society Transactions 35 (2), 273-276, 2007 | 68 | 2007 |
Targeting proteases in cystic fibrosis lung disease. Paradigms, progress, and potential MC McKelvey, S Weldon, DF McAuley, MA Mall, CC Taggart American Journal of Respiratory and Critical Care Medicine 201 (2), 141-147, 2020 | 64 | 2020 |
Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics R Brown, S Nath, A Lora, G Samaha, Z Elgamal, R Kaiser, C Taggart, ... Respiratory Research 21, 1-17, 2020 | 56 | 2020 |
Fasciola hepatica-derived molecules as regulators of the host immune response S Ryan, JP Dalton Frontiers in immunology 11, 576753, 2020 | 56 | 2020 |
Proteases and their inhibitors in chronic obstructive pulmonary disease T Dey, J Kalita, S Weldon, CC Taggart Journal of clinical medicine 7 (9), 244, 2018 | 56 | 2018 |
Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages S Weldon, S Mitchell, D Kelleher, MJ Gibney, HM Roche Atherosclerosis 174 (2), 261-273, 2004 | 52 | 2004 |
Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens JE Payne, AV Dubois, RJ Ingram, S Weldon, CC Taggart, JS Elborn, ... International Journal of Antimicrobial Agents 50 (3), 427-435, 2017 | 50 | 2017 |
Mechanisms of virus-induced airway immunity dysfunction in the pathogenesis of COPD disease, progression, and exacerbation H Guo-Parke, D Linden, S Weldon, JC Kidney, CC Taggart Frontiers in Immunology 11, 516782, 2020 | 46 | 2020 |
Airway inflammation and host responses in the era of CFTR modulators K Keown, R Brown, DF Doherty, C Houston, MC McKelvey, S Creane, ... International journal of molecular sciences 21 (17), 6379, 2020 | 44 | 2020 |