Nitric oxide synthases: structure, function and inhibition WK Alderton, CE Cooper, RG Knowles Biochemical journal 357 (3), 593-615, 2001 | 5699 | 2001 |
Nitric oxide synthases in mammals. RG Knowles, S Moncada Biochemical Journal 298 (Pt 2), 249, 1994 | 3885 | 1994 |
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. RG Knowles, M Palacios, RM Palmer, S Moncada Proceedings of the National Academy of Sciences 86 (13), 5159-5162, 1989 | 1860 | 1989 |
Induction of calcium-dependent nitric oxide synthases by sex hormones. CP Weiner, I Lizasoain, SA Baylis, RG Knowles, IG Charles, S Moncada Proceedings of the National Academy of Sciences 91 (11), 5212-5216, 1994 | 1426 | 1994 |
1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo EP Garvey, JA Oplinger, ES Furfine, RJ Kiff, F Laszlo, BJR Whittle, ... Journal of Biological Chemistry 272 (8), 4959-4963, 1997 | 1013 | 1997 |
Nitric oxide synthase activity in human breast cancer LL Thomsen, DW Miles, L Happerfield, LG Bobrow, RG Knowles, ... British journal of cancer 72 (1), 41-44, 1995 | 843 | 1995 |
Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases M Salter, RG Knowles, S Moncada FEBS letters 291 (1), 145-149, 1991 | 788 | 1991 |
Nitric oxide synthase activity in human gynecological cancer LL Thomsen, FG Lawton, RG Knowles, JE Beesley, V Riveros-Moreno, ... Cancer research 54 (5), 1352-1354, 1994 | 624 | 1994 |
Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat RG Knowles, M Salter, SL Brooks, S Moncada Biochemical and biophysical research communications 172 (3), 1042-1048, 1990 | 511 | 1990 |
Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. RG Knowles, M Merrett, M Salter, S Moncada Biochemical Journal 270 (3), 833, 1990 | 494 | 1990 |
Nitric oxide as a signal in blood vessels RG Knowles, S Moncada Trends in biochemical sciences 17 (10), 399-402, 1992 | 454 | 1992 |
Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline. AM Leone, RM Palmer, RG Knowles, PL Francis, DS Ashton, S Moncada Journal of Biological Chemistry 266 (35), 23790-23795, 1991 | 403 | 1991 |
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose I LIZASOAIN, MA MORO, RG KNOWLES, V DARLEY-USMAR, ... Biochemical Journal 314 (3), 877-880, 1996 | 399 | 1996 |
Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands M Palacios, RG Knowles, RMJ Palmer, S Moncada Biochemical and biophysical research communications 165 (2), 802-809, 1989 | 333 | 1989 |
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ... Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017 | 291 | 2017 |
Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline. ES Furfine, MF Harmon, JE Paith, RG Knowles, M Salter, RJ Kiff, C Duffy, ... Journal of Biological Chemistry 269 (43), 26677-26683, 1994 | 266 | 1994 |
Selective Inhibition of Inducible Nitric Oxide Synthase Inhibits Tumor Growth in Vivo: Studies with 1400W, a Novel Inhibitor LL Thomsen, JMJ Scott, P Topley, RG Knowles, AJ Keerie, AJ Frend Cancer research 57 (15), 3300-3304, 1997 | 265 | 1997 |
Kinetic characteristics of nitric oxide synthase from rat brain RG Knowles, M Palacios, RMJ Palmer, S Moncada Biochemical Journal 269 (1), 207-210, 1990 | 264 | 1990 |
The formation of nitric oxide donors from peroxynitrite MÁ Moro, VM Darley‐Usmar, I Lizasoain, Y Su, RG Knowles, S Moncada, ... British journal of pharmacology 116 (3), 1999-2004, 1995 | 240 | 1995 |
Induction of nitric oxide synthases early in pregnancy CP Weiner, RG Knowles, S Moncada American journal of obstetrics and gynecology 171 (3), 838-843, 1994 | 213 | 1994 |