Chemical proteomics approaches for identifying the cellular targets of natural products MH Wright, SA Sieber Natural product reports 33 (5), 681-708, 2016 | 421 | 2016 |
Protein myristoylation in health and disease MH Wright, WP Heal, DJ Mann, EW Tate Journal of chemical biology 3, 19-35, 2010 | 308 | 2010 |
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ... Nature communications 5, 4919, 2014 | 260 | 2014 |
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ... Nature chemistry 6 (2), 112-121, 2014 | 241 | 2014 |
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ... Cell host & microbe 16 (1), 128-140, 2014 | 132 | 2014 |
Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry WP Heal, MH Wright, E Thinon, EW Tate Nature protocols 7 (1), 105-117, 2012 | 119 | 2012 |
Bioorthogonal chemical tagging of protein cholesterylation in living cells WP Heal, B Jovanovic, S Bessin, MH Wright, AI Magee, EW Tate Chemical Communications 47 (14), 4081-4083, 2011 | 102 | 2011 |
Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani MH Wright, D Paape, EM Storck, RA Serwa, DF Smith, EW Tate Chemistry & biology 22 (3), 342-354, 2015 | 100 | 2015 |
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, ... Organic & biomolecular chemistry 10 (42), 8452-8464, 2012 | 94 | 2012 |
Catalase: A critical node in the regulation of cell fate A Baker, CC Lin, C Lett, B Karpinska, MH Wright, CH Foyer Free Radical Biology and Medicine 199, 56-66, 2023 | 90 | 2023 |
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, ... Organic & biomolecular chemistry 10 (30), 6032-6044, 2012 | 85 | 2012 |
N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis EW Tate, AS Bell, MD Rackham, MH Wright Parasitology 141 (1), 37-49, 2014 | 82 | 2014 |
Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors JA Hutton, V Goncalves, JA Brannigan, D Paape, MH Wright, TM Waugh, ... Journal of medicinal chemistry 57 (20), 8664-8670, 2014 | 75 | 2014 |
Redox regulation of cell proliferation: Bioinformatics and redox proteomics approaches to identify redox-sensitive cell cycle regulators CH Foyer, MH Wilson, MH Wright Free Radical Biology and Medicine 122, 137-149, 2018 | 73 | 2018 |
Making a Long Journey Short: Alkyne Functionalization of Natural Product Scaffolds J Lehmann, MH Wright, SA Sieber Chemistry-A European Journal 22 (14), 4666-4678, 2016 | 72 | 2016 |
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite B Poulin, EM Patzewitz, D Brady, O Silvie, MH Wright, DJP Ferguson, ... Biology open 2 (11), 1160-1170, 2013 | 68 | 2013 |
Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei MH Wright, D Paape, HP Price, DF Smith, EW Tate ACS infectious diseases 2 (6), 427-441, 2016 | 61 | 2016 |
On the move: redox-dependent protein relocation in plants CH Foyer, A Baker, M Wright, IA Sparkes, A Mhamdi, JHM Schippers, ... Journal of experimental botany 71 (2), 620-631, 2020 | 54 | 2020 |
Chemical probes unravel an antimicrobial defense response triggered by binding of the human opioid dynorphin to a bacterial sensor kinase MH Wright, C Fetzer, SA Sieber Journal of the American Chemical Society 139 (17), 6152-6159, 2017 | 51 | 2017 |
New developments in probing and targeting protein acylation in malaria, leishmaniasis and African sleeping sickness M Ritzefeld, MH Wright, EW Tate Parasitology 145 (2), 157-174, 2018 | 39 | 2018 |