|A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β|
JJ Iliff, M Wang, Y Liao, BA Plogg, W Peng, GA Gundersen, H Benveniste, ...
Science translational medicine 4 (147), 147ra111-147ra111, 2012
|Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain|
S Nielsen, EA Nagelhus, M Amiry-Moghaddam, C Bourque, P Agre, ...
Journal of Neuroscience 17 (1), 171-180, 1997
|Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in …|
EA Nagelhus, Y Horio, A Inanobe, A Fujita, F Haug, S Nielsen, Y Kurachi, ...
Glia 26 (1), 47-54, 1999
|Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4. 1|
EA Nagelhus, TM Mathiisen, OP Ottersen
Neuroscience 129 (4), 905-913, 2004
|Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes|
EA Nagelhus, ML Veruki, R Torp, FM Haug, JH Laake, S Nielsen, P Agre, ...
Journal of Neuroscience 18 (7), 2506-2519, 1998
|Physiological roles of aquaporin-4 in brain|
EA Nagelhus, OP Ottersen
Physiological reviews 93 (4), 1543-1562, 2013
|Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of α-syntrophin-null mice|
M Amiry-Moghaddam, A Williamson, M Palomba, T Eid, NC De Lanerolle, ...
Proceedings of the National Academy of Sciences 100 (23), 13615-13620, 2003
|Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye|
S Hamann, T Zeuthen, ML Cour, EA Nagelhus, OP Ottersen, P Agre, ...
American Journal of Physiology-Cell Physiology 274 (5), C1332-C1345, 1998
|Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema|
AS Thrane, PM Rappold, T Fujita, A Torres, LK Bekar, T Takano, W Peng, ...
Proceedings of the National Academy of Sciences 108 (2), 846-851, 2011
|Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet|
NN Haj-Yasein, GF Vindedal, M Eilert-Olsen, GA Gundersen, Ĝ Skare, ...
Proceedings of the National Academy of Sciences 108 (43), 17815-17820, 2011
|General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex|
AS Thrane, VR Thrane, D Zeppenfeld, N Lou, Q Xu, EA Nagelhus, ...
Proceedings of the National Academy of Sciences 109 (46), 18974-18979, 2012
|Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering|
VR Thrane, AS Thrane, F Wang, ML Cotrina, NA Smith, M Chen, Q Xu, ...
Nature medicine 19 (12), 1643-1648, 2013
|Ontogeny of water transport in rat brain: postnatal expression of the aquaporin‐4 water channel|
H Wen, EA Nagelhus, M Amiry‐Moghaddam, P Agre, OP Ottersen, ...
European Journal of Neuroscience 11 (3), 935-945, 1999
|Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat|
L Bergersen, E Johannsson, ML Veruki, EA Nagelhus, A Halestrap, ...
Neuroscience 90 (1), 319-331, 1999
|Aquaporin‐4 and epilepsy|
DK Binder, EA Nagelhus, OP Ottersen
Glia 60 (8), 1203-1214, 2012
|Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10)|
NN Haj‐Yasein, V Jensen, GF Vindedal, GA Gundersen, A Klungland, ...
Glia 59 (11), 1635-1642, 2011
|Neuronal-glial exchange of taurine during hypo-osmotic stress: a combined immunocytochemical and biochemical analysis in rat cerebellar cortex|
EA Nagelhus, A Lehmann, OP Ottersen
Neuroscience 54 (3), 615-631, 1993
|Select types of supporting cell in the inner ear express aquaporin‐4 water channel protein|
Y Takumi, EA Nagelhus, J Eidet, A Matsubara, S Usami, H Shinkawa, ...
European Journal of Neuroscience 10 (12), 3584-3595, 1998
|Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain|
VR Thrane, AS Thrane, BA Plog, M Thiyagarajan, JJ Iliff, R Deane, ...
Scientific reports 3, 2582, 2013
|Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow|
KE Holter, B Kehlet, A Devor, TJ Sejnowski, AM Dale, SW Omholt, ...
Proceedings of the National Academy of Sciences 114 (37), 9894-9899, 2017