Follow
Debra Josephs MBChB, PhD, MRCP
Debra Josephs MBChB, PhD, MRCP
Consultant Medical Oncologist
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Targeting folate receptor alpha for cancer treatment
A Cheung, HJ Bax, DH Josephs, KM Ilieva, G Pellizzari, J Opzoomer, ...
Oncotarget 7 (32), 52553, 2016
4222016
Combining immune checkpoint inhibitors: established and emerging targets and strategies to improve outcomes in melanoma
DO Khair, HJ Bax, S Mele, S Crescioli, G Pellizzari, A Khiabany, ...
Frontiers in immunology 10, 453, 2019
2242019
IgG4 subclass antibodies impair antitumor immunity in melanoma
P Karagiannis, AE Gilbert, DH Josephs, N Ali, T Dodev, L Saul, I Correa, ...
The Journal of clinical investigation 123 (4), 1457-1474, 2013
2232013
Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers
SA Harding, J Sarma, DH Josephs, NL Cruden, JN Din, PJ Twomey, ...
Circulation 109 (16), 1926-1929, 2004
1602004
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ...
Cancer cell 39 (11), 1497-1518. e11, 2021
1502021
Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)
RM Hoffmann, BGT Coumbe, DH Josephs, S Mele, KM Ilieva, A Cheung, ...
Oncoimmunology 7 (3), e1395127, 2018
1502018
Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment
M Georgouli, C Herraiz, E Crosas-Molist, B Fanshawe, O Maiques, ...
Cell 176 (4), 757-774. e23, 2019
1432019
A tool kit for rapid cloning and expression of recombinant antibodies
TS Dodev, P Karagiannis, AE Gilbert, DH Josephs, H Bowen, LK James, ...
Scientific reports 4 (1), 5885, 2014
1132014
Epidemiological associations of allergy, IgE and cancer
DH Josephs, JF Spicer, CJ Corrigan, HJ Gould, SN Karagiannis
Clinical & Experimental Allergy 43 (10), 1110-1123, 2013
1052013
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action
ZN Willsmore, BGT Coumbe, S Crescioli, S Reci, A Gupta, RJ Harris, ...
European Journal of Immunology 51 (3), 544-556, 2021
1032021
BRAF inhibitors: resistance and the promise of combination treatments for melanoma
M Griffin, D Scotto, DH Josephs, S Mele, S Crescioli, HJ Bax, G Pellizzari, ...
Oncotarget 8 (44), 78174, 2017
1032017
Clinical pharmacokinetics of tyrosine kinase inhibitors: implications for therapeutic drug monitoring
DH Josephs, DS Fisher, J Spicer, RJ Flanagan
Therapeutic drug monitoring 35 (5), 562-587, 2013
1032013
Effects of BRAF Mutations and BRAF Inhibition on Immune Responses to Melanoma
KM Ilieva, I Correa, DH Josephs, P Karagiannis, IU Egbuniwe, ...
Molecular cancer therapeutics 13 (12), 2769-2783, 2014
952014
Flow cytometric analysis of circulating platelet-monocyte aggregates in whole blood: methodological considerations
SA Harding, JN Din, J Sarma, A Jessop, M Weatherall, KAA Fox, ...
Thrombosis and haemostasis 98 (08), 451-456, 2007
942007
Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies
AE Gilbert, P Karagiannis, T Dodev, A Koers, K Lacy, DH Josephs, ...
PloS one 6 (4), e19330, 2011
912011
AllergoOncology–the impact of allergy in oncology: EAACI position paper
E Jensen‐Jarolim, HJ Bax, R Bianchini, M Capron, C Corrigan, M Castells, ...
Allergy 72 (6), 866-887, 2017
852017
An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography–tandem mass spectrometry
L Couchman, M Birch, R Ireland, A Corrigan, S Wickramasinghe, ...
Analytical and bioanalytical chemistry 403, 1685-1695, 2012
802012
Tumour-associated macrophage polarisation and re-education with immunotherapy
DH Josephs, HJ Bax, SN Karagiannis
Front Biosci (Elite Ed) 7 (2), 293-308, 2015
792015
Anti-folate receptor alpha–directed antibody therapies restrict the growth of triple-negative breast cancer
A Cheung, J Opzoomer, KM Ilieva, P Gazinska, RM Hoffmann, H Mirza, ...
Clinical Cancer Research 24 (20), 5098-5111, 2018
782018
Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFα/MCP-1 signaling
DH Josephs, HJ Bax, T Dodev, M Georgouli, M Nakamura, G Pellizzari, ...
Cancer research 77 (5), 1127-1141, 2017
732017
The system can't perform the operation now. Try again later.
Articles 1–20