Vincent Lemaire

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	All	Since 2019
Citations	1318	629
h-index	9	7
i10-index	9	7

140

105

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Co-authors

Jacques Bélairuniversité de montréalVerified email at dms.umontreal.ca
Jin Y. JinExecutive Director and Senior Fellow, Head of M&S, Clinical Pharmacology, GenentechVerified email at gene.com
Larry SuvaProfessor, Texas A&M UniversityVerified email at cvm.tamu.edu
Dirk RooseKU LeuvenVerified email at kuleuven.be
Jinzhi LeiSchool of Mathematical Science, Tiangong UniversityVerified email at tiangong.edu.cn
Leon GlassProfessor of Physiology, McGill UniversityVerified email at mcgill.ca
Chiu Fan LeeDepartment of Bioengineering, Imperial College LondonVerified email at imperial.ac.uk
Yi Ting (Kayla) LienGenentechVerified email at gene.com
Dean BottinoSenior Scientific Director, Takeda PharmaceuticalsVerified email at takeda.com
Lu HuangBristol-Myers SquibbVerified email at bms.com
Vinayak SantAssociate Professor, University of PittsburghVerified email at pitt.edu
Lafaye de MicheauxAssociate Professor, UNSW SydneyVerified email at unsw.edu.au
Jack TuszyńskiPolitecnico di TorinoVerified email at polito.it
Michael C. MackeyProfessor emeritusVerified email at mcgill.ca
Moisés SantillánCentro de Investigación y de Estudios Avanzados del IPN (Cinvestav)Verified email at cinvestav.mx
Caroline ColijnSimon Fraser University, Department of MathematicsVerified email at sfu.ca
Peter PivonkaQueensland University of Technology, School of Mechanical, Medical and Process EngineeringVerified email at qut.edu.au
Adilson E. MotterProfessor of Physics and Astronomy, Northwestern UniversityVerified email at northwestern.edu
Fahima NekkaFull Professor, Faculty of Pharmacy, Université de Montréal

Vincent Lemaire

Distinguished Scientist, Clinical Pharmacology, Systems Modeling Lead, Genentech

Verified email at gene.com

Mathematical modeling - Computational biology - Biological regulatory processes - Mechanistic PK/PD


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Modeling the interactions between osteoblast and osteoclast activities in bone remodeling V Lemaire, FL Tobin, LD Greller, CR Cho, LJ Suva Journal of theoretical biology 229 (3), 293-309, 2004	569	2004
Mechanistic overview of immune checkpoints to support the rational design of their combinations in cancer immunotherapy A Rotte, JY Jin, V Lemaire Annals of Oncology 29 (1), 71-83, 2018	355	2018
Structural modeling of drug release from biodegradable porous matrices based on a combined diffusion/erosion process V Lemaire, J Belair, P Hildgen International journal of pharmaceutics 258 (1-2), 95-107, 2003	158	2003
Numerical bifurcation analysis of delay differential equations arising from physiological modeling K Engelborghs, V Lemaire, J Belair, D Roose Journal of mathematical biology 42, 361-385, 2001	116	2001
Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation V Lemaire, CF Lee, J Lei, R Métivier, L Glass Physical review letters 96 (19), 198102, 2006	39	2006
Pharmacology-based ranking of anti-cancer drugs to guide clinical development of cancer immunotherapy combinations V Lemaire, CS Shemesh, A Rotte Journal of Experimental & Clinical Cancer Research 40 (1), 311, 2021	35	2021
Dynamics of Bone Cell Interactions and Differential Responses to PTH and Antibody-Based Therapies V Lemaire, DR Cox Bulletin of Mathematical Biology, 1–48, 2018	12	2018
From cold to hot: changing perceptions and future opportunities for quantitative systems pharmacology modeling in cancer immunotherapy V Lemaire, D Bassen, M Reed, R Song, S Khalili, YT Lien, L Huang, ... Clinical Pharmacology & Therapeutics 113 (5), 963-972, 2023	11	2023
Spatial effects in modeling pharmacokinetics of rapid action drugs P Lafrance, V Lemaire, F Varin, F Donati, J Bélair, F Nekka Bulletin of mathematical biology 64 (3), 483-500, 2002	11	2002
Bilayer Composition for the Sustained Release of Acetaminophen and Tramadol A Bichara, S Gervais, D Le Garrec, P Ouadji, V Sant, S Gosein, V Lemaire, ... US Patent App. 12/252,117, 2008	8*	2008
Modeling and simulation to optimize efficacy and tolerability for once a day trazodone formulation V Lemaire, C Benquet, D LeGarrec, SD Robertson Sy, SM Stahl Abstract presented at: The European College of Neuropsychopharmacology meeting, 2009	3*	2009
Sample Size Determination and Statistical Hypothesis Testing for Core Centration in Press Coated Tablets PL de Micheaux, V Lemaire Open Journal of Statistics 2 (3), 269-273, 2012	1	2012
No Recipe for Quantitative Systems Pharmacology Model Validation, but a Balancing Act Between Risk and Cost V Lemaire, C Hu, PH van der Graaf, S Chang, W Wang Clinical Pharmacology & Therapeutics 115 (1), 25-28, 2024		2024
IDENTIFYING BIOLOGICAL SIGNALS DIFFERENTIATING RESPONDERS AND NON-RESPONDERS TO MPDL3280A (ANTI-PDL1) IN NON-SMALL CELL LUNG CANCER USING QUANTITATIVE SYSTEMS PHARMACOLOGY … V Lemaire, A Rotte, K Gadkar, JY Jin, S Ramanujan CLINICAL PHARMACOLOGY & THERAPEUTICS 105, S119-S119, 2019		2019
Modélisation de la libération de substances bioactives et des conséquences sur la dynamique physiologique V Lemaire University of Montreal, 2003		2003

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