Matthew M Heberling
Matthew M Heberling
Cofounder at Peptone. Rationalizing failed data for better medicines.
Verified email at peptone.io - Homepage
TitleCited byYear
Priming ammonia lyases and aminomutases for industrial and therapeutic applications
MM Heberling, B Wu, S Bartsch, DB Janssen
Current opinion in chemical biology 17 (2), 250-260, 2013
702013
Mechanism‐Inspired Engineering of Phenylalanine Aminomutase for Enhanced β‐Regioselective Asymmetric Amination of Cinnamates
B Wu, W Szymański, GG Wybenga, MM Heberling, S Bartsch, ...
Angewandte Chemie International Edition 51 (2), 482-486, 2012
472012
Aminomutases: mechanistic diversity, biotechnological applications and future perspectives
B Wu, W Szymański, MM Heberling, BL Feringa, DB Janssen
Trends in biotechnology 29 (7), 352-362, 2011
382011
Redesign of a phenylalanine aminomutase into a phenylalanine ammonia lyase
S Bartsch, GG Wybenga, M Jansen, MM Heberling, B Wu, BW Dijkstra, ...
ChemCatChem 5 (7), 1797-1802, 2013
222013
DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
A Batyuk, Y Wu, A Honegger, MM Heberling, A Plückthun
Journal of Molecular Biology 428 (8), 1574-1588, 2016
192016
Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase
MM Heberling, MF Masman, S Bartsch, GG Wybenga, BW Dijkstra, ...
ACS chemical biology 10 (4), 989-997, 2015
172015
Metabolism of β-valine via a CoA-dependent ammonia lyase pathway
M Otzen, CG Crismaru, CP Postema, HJ Wijma, MM Heberling, ...
Applied microbiology and biotechnology 99 (21), 8987-8998, 2015
32015
Structural Propensity Database of Proteins
K Tamiola, MM Heberling, J Domanski
bioRxiv.org 144840, 2017
2017
Genomic-based Discovery and Engineering of Biocatalysts for Conversion of Amines
MM Heberling
University of Groningen, 2017
2017
From Aminomutases to Ammonia Lyases: A Protein Engineering Study
MF Masman, MM Heberling, DB Janssen
Biophysical Journal 106 (2), 655a, 2014
2014
Toward a Global View of the Conformational Landscape of the Human Kinome
DL Parton, D Shukla, Y Zhao, VS Pande, JD Chodera
Biophysical Journal 106 (2), 655a-656a, 2014
2014
Computation-supported enzyme engineering for preparative biocatalysis
D Janssen, R Floor, M Heberling, S Bartsch, H Wijma
The Febs Journal 280 (1), 591-592, 2013
2013
PAM/PAL review
MM Heberling, B Wu, S Bartsch, DB Janssen
Current Opinion in Chemical Biology 17 (250), 2013
2013
Engineering promiscuous lyases for enantioselective biocatalysis
DB Janssen, B Wu, S Bartsch, MM Heberling, W Szymanski, CG Crismaru
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012
2012
Improving Stability of Tumor Suppressor Protein, p53
M Heberling
The Ohio State University, 2007
2007
Full wwPDB X-ray Structure Validation Report i○
RT Guo, TP Ko, R Cao, PH Liang, E Oldfield, AHJ Wang
From Aminomutases to Ammonia Lyases
MF Masman, MM Heberling, D Janssen
Redesign of a PAM into a PAL
S Bartsch, GG Wybenga, M Jansen, MM Heberling, B Wu, BW Dijkstra, ...
Transaminases
MM Heberling, C Postema, MF Masman, W Wang, TJ Meijer, DB Janssen
Genome mining
MM Heberling, CP Postema, TJ Meijer, M Otzen, D Wibberg, J Blom, ...
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