| Role of protein–protein interactions in cytochrome P450-mediated drug metabolism and toxicity SE Kandel, JN Lampe Chemical research in toxicology 27 (9), 1474-1486, 2014 | 86 | 2014 |
| The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid-and perfluorooctanesulfonic acid-induced hepatocellular dysfunction KM Beggs, SR McGreal, A McCarthy, S Gunewardena, JN Lampe, C Lau, ... Toxicology and applied pharmacology 304, 18-29, 2016 | 80 | 2016 |
| Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake KH Boxberger, B Hagenbuch, JN Lampe Drug Metabolism and Disposition 42 (6), 990-995, 2014 | 72 | 2014 |
| Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism H Li, JN Lampe Archives of biochemistry and biophysics 673, 108078, 2019 | 49 | 2019 |
| Digging deeper into CYP3A testosterone metabolism: kinetic, regioselectivity, and stereoselectivity differences between CYP3A4/5 and CYP3A7 SE Kandel, LW Han, Q Mao, JN Lampe Drug Metabolism and Disposition 45 (12), 1266-1275, 2017 | 48 | 2017 |
| Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates JN Lampe, R Brandman, S Sivaramakrishnan, PRO de Montellano Journal of biological chemistry 285 (13), 9594-9603, 2010 | 48 | 2010 |
| Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4 JN Lampe, C Fernandez, A Nath, WM Atkins Biochemistry 47 (2), 509-516, 2008 | 43 | 2008 |
| Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation CD Williams, MR Koerner, JN Lampe, A Farhood, H Jaeschke Toxicology and applied pharmacology 257 (3), 449-458, 2011 | 41 | 2011 |
| Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4 JN Lampe, WM Atkins Biochemistry 45 (40), 12204-12215, 2006 | 40 | 2006 |
| Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid 13C-p-methoxyphenylalanine JN Lampe, SN Floor, JD Gross, CR Nishida, Y Jiang, MJ Trnka, ... Journal of the American Chemical Society 130 (48), 16168-16169, 2008 | 39 | 2008 |
| Antisense oligonucleotides containing modified bases inhibit in vitro translation of Leishmania amazonensis mRNAs by invading the mini-exon hairpin D Compagno, JN Lampe, C Bourget, IV Kutyavin, L Yurchenko, ... Journal of Biological Chemistry 274 (12), 8191-8198, 1999 | 36 | 1999 |
| Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography D Basudhar, Y Madrona, S Kandel, JN Lampe, CR Nishida, ... Journal of Biological Chemistry 290 (16), 10000-10017, 2015 | 32 | 2015 |
| Role of cysteine residues in heme binding to human heme oxygenase-2 elucidated by two-dimensional NMR spectroscopy F Varfaj, JN Lampe, PRO de Montellano Journal of Biological Chemistry 287 (42), 35181-35191, 2012 | 30 | 2012 |
| NMR Studies of Ligand Binding to P450eryF Provides Insight into the Mechanism of Cooperativity AG Roberts, MD Díaz, JN Lampe, LM Shireman, JS Grinstead, ... Biochemistry 45 (6), 1673-1684, 2006 | 29 | 2006 |
| Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase B Wen, JN Lampe, AG Roberts, WM Atkins, AD Rodrigues, SD Nelson Archives of biochemistry and biophysics 454 (1), 42-54, 2006 | 26 | 2006 |
| Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel KH Boxberger, B Hagenbuch, JN Lampe Biochemical pharmacology 156, 371-384, 2018 | 25 | 2018 |
| Factors influencing the extent and selectivity of alkylation within triplexes by reactive G/A motif oligonucleotides JN Lampe, IV Kutyavin, R Rhinehart, MW Reed, RB Meyer, HB Gamper Nucleic acids research 25 (20), 4123-4131, 1997 | 23 | 1997 |
| Active-site residues move independently from the rest of the protein in a 200 ns molecular dynamics simulation of cytochrome P450 CYP119 R Brandman, JN Lampe, Y Brandman, PRO de Montellano Archives of biochemistry and biophysics 509 (2), 127-132, 2011 | 21 | 2011 |
| Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4 A Nath, C Fernández, JN Lampe, WM Atkins Archives of biochemistry and biophysics 474 (1), 198-204, 2008 | 19 | 2008 |
| Advances in the understanding of protein-protein interactions in drug metabolizing enzymes through the use of biophysical techniques JN Lampe Frontiers in Pharmacology 8, 272814, 2017 | 15 | 2017 |
