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Linda V. Sinclair
Linda V. Sinclair
Verified email at dundee.ac.uk
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Cited by
Cited by
Year
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
LV Sinclair, J Rolf, E Emslie, YB Shi, PM Taylor, DA Cantrell
Nature immunology 14 (5), 500-508, 2013
6772013
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
DK Finlay, E Rosenzweig, LV Sinclair, C Feijoo-Carnero, JL Hukelmann, ...
Journal of Experimental Medicine 209 (13), 2441-2453, 2012
5132012
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ...
Nature immunology 9 (5), 513-521, 2008
4112008
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ...
Nature immunology 9 (5), 513-521, 2008
4102008
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
AN Macintyre, D Finlay, G Preston, LV Sinclair, CM Waugh, P Tamas, ...
Immunity 34 (2), 224-236, 2011
2532011
Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
M Swamy, S Pathak, KM Grzes, S Damerow, LV Sinclair, DMF van Aalten, ...
Nature immunology 17 (6), 712-720, 2016
2392016
Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
M Swamy, S Pathak, KM Grzes, S Damerow, LV Sinclair, DMF van Aalten, ...
Nature immunology 17 (6), 712-720, 2016
2392016
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells
LJ Pallett, US Gill, A Quaglia, LV Sinclair, M Jover-Cobos, A Schurich, ...
Nature medicine 21 (6), 591-600, 2015
2342015
Differential regulation of T-cell growth by IL-2 and IL-15
GH Cornish, LV Sinclair, DA Cantrell
Blood 108 (2), 600-608, 2006
1842006
Differential regulation of T-cell growth by IL-2 and IL-15
GH Cornish, LV Sinclair, DA Cantrell
Blood 108 (2), 600-608, 2006
1842006
The cytotoxic T cell proteome and its shaping by the kinase mTOR
JL Hukelmann, KE Anderson, LV Sinclair, KM Grzes, AB Murillo, ...
Nature immunology 17 (1), 104-112, 2016
1712016
The cytotoxic T cell proteome and its shaping by the kinase mTOR
JL Hukelmann, KE Anderson, LV Sinclair, KM Grzes, AB Murillo, ...
Nature immunology 17 (1), 104-112, 2016
1712016
Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
RM Loftus, N Assmann, N Kedia-Mehta, KL O’Brien, A Garcia, C Gillespie, ...
Nature communications 9 (1), 1-15, 2018
1602018
Single cell tuning of Myc expression by antigen receptor signal strength and interleukin‐2 in T lymphocytes
GC Preston, LV Sinclair, A Kaskar, JL Hukelmann, MN Navarro, I Ferrero, ...
The EMBO journal 34 (15), 2008-2024, 2015
1152015
Glucose represses dendritic cell-induced T cell responses
SJ Lawless, N Kedia-Mehta, JF Walls, R McGarrigle, O Convery, ...
Nature communications 8 (1), 1-14, 2017
932017
Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation
AJM Howden, JL Hukelmann, A Brenes, L Spinelli, LV Sinclair, ...
Nature immunology 20 (11), 1542-1554, 2019
902019
Phosphoinositide (3, 4, 5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not …
C Waugh, L Sinclair, D Finlay, JR Bayascas, D Cantrell
Molecular and cellular biology 29 (21), 5952-5962, 2009
902009
Antigen receptor control of methionine metabolism in T cells
LV Sinclair, AJM Howden, A Brenes, L Spinelli, JL Hukelmann, ...
Elife 8, e44210, 2019
822019
Single cell analysis of kynurenine and System L amino acid transport in T cells
LV Sinclair, D Neyens, G Ramsay, PM Taylor, DA Cantrell
Nature communications 9 (1), 1-11, 2018
822018
Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells
SA Matthews, MN Navarro, LV Sinclair, E Emslie, C Feijoo-Carnero, ...
Biochemical Journal 432 (1), 153-163, 2010
802010
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