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Jurgen Wess
Jurgen Wess
NIH-NIDDK
Verified email at niddk.nih.gov
Title
Cited by
Cited by
Year
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
9892013
Structure and dynamics of the M3 muscarinic acetylcholine receptor
AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ...
Nature 482 (7386), 552-556, 2012
9342012
G‐protein‐coupled receptors: molecular mechanisms involved in receptor activation and selectivity of G‐protein recognition
J Wess
The FASEB Journal 11 (5), 346-354, 1997
8771997
Antagonist binding profiles of five cloned human muscarinic receptor subtypes
F Dörje, J Wess, G Lambrecht, R Tacke, E Mutschler, MR Brann
7801991
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
J Wess, RM Eglen, D Gautam
Nature reviews Drug discovery 6 (9), 721-733, 2007
7422007
Molecular biology of muscarinic acetylcholine receptors
J Wess
Critical Reviews™ in Neurobiology 10 (1), 1996
6481996
Molecular basis of receptor/G-protein-coupling selectivity
J Wess
Pharmacology & therapeutics 80 (3), 231-264, 1998
6271998
Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications
J Wess
Annu. Rev. Pharmacol. Toxicol. 44 (1), 423-450, 2004
4882004
Muscarinic acetylcholine receptors: novel opportunities for drug development
AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess
Nature reviews Drug discovery 13 (7), 549-560, 2014
4642014
Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean
M Yamada, T Miyakawa, A Duttaroy, A Yamanaka, T Moriguchi, R Makita, ...
Nature 410 (6825), 207-212, 2001
4642001
Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice
J Gomeza, H Shannon, E Kostenis, C Felder, L Zhang, J Brodkin, ...
Proceedings of the National Academy of Sciences 96 (4), 1692-1697, 1999
4571999
Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular" cross-talk" between G-protein-linked receptors.
R Maggio, Z Vogel, J Wess
Proceedings of the National Academy of Sciences 90 (7), 3103-3107, 1993
4471993
Hyperactivity and intact hippocampus-dependent learning in mice lacking the M1 muscarinic acetylcholine receptor
T Miyakawa, M Yamada, A Duttaroy, J Wess
Journal of Neuroscience 21 (14), 5239-5250, 2001
4402001
Lack of beta-arrestin signaling in the absence of active G proteins
M Grundmann, N Merten, D Malfacini, A Inoue, P Preis, K Simon, ...
Nature communications 9 (1), 341, 2018
3952018
A chemical-genetic approach to study G protein regulation of β cell function in vivo
JM Guettier, D Gautam, M Scarselli, IR de Azua, JH Li, E Rosemond, X Ma, ...
Proceedings of the National Academy of Sciences 106 (45), 19197-19202, 2009
3942009
Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice
W Zhang, AS Basile, J Gomeza, LA Volpicelli, AI Levey, J Wess
Journal of Neuroscience 22 (5), 1709-1717, 2002
3862002
Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M4 muscarinic acetylcholine receptor knockout mice
J Gomeza, L Zhang, E Kostenis, C Felder, F Bymaster, J Brodkin, ...
Proceedings of the National Academy of Sciences 96 (18), 10483-10488, 1999
3851999
Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice
M Yamada, KG Lamping, A Duttaroy, W Zhang, Y Cui, FP Bymaster, ...
Proceedings of the National Academy of Sciences 98 (24), 14096-14101, 2001
3532001
Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation
G Trivellin, AF Daly, FR Faucz, B Yuan, L Rostomyan, DO Larco, ...
New England Journal of Medicine 371 (25), 2363-2374, 2014
3472014
A critical role for β cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
D Gautam, SJ Han, FF Hamdan, J Jeon, B Li, JH Li, Y Cui, D Mears, H Lu, ...
Cell metabolism 3 (6), 449-461, 2006
3462006
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