| Defective mitophagy in XPA via PARP-1 hyperactivation and NAD+/SIRT1 reduction EF Fang, M Scheibye-Knudsen, LE Brace, H Kassahun, T SenGupta, ... Cell 157 (4), 882-896, 2014 | 360 | 2014 |
| Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ... Nature neuroscience 22 (3), 401-412, 2019 | 258 | 2019 |
| Mitophagy and Alzheimer’s disease: cellular and molecular mechanisms JS Kerr, BA Adriaanse, NH Greig, MP Mattson, MZ Cader, VA Bohr, ... Trends in neurosciences 40 (3), 151-166, 2017 | 227 | 2017 |
| A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 209 | 2014 |
| Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 203 | 2016 |
| NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair EF Fang, H Kassahun, DL Croteau, M Scheibye-Knudsen, K Marosi, H Lu, ... Cell metabolism 24 (4), 566-581, 2016 | 198 | 2016 |
| Protecting the mitochondrial powerhouse M Scheibye-Knudsen, EF Fang, DL Croteau, DM Wilson III, VA Bohr Trends in cell biology 25 (3), 158-170, 2015 | 195 | 2015 |
| Nuclear DNA damage signalling to mitochondria in ageing EF Fang, M Scheibye-Knudsen, KF Chua, MP Mattson, DL Croteau, ... Nature reviews Molecular cell biology 17 (5), 308-321, 2016 | 192 | 2016 |
| DNA Damage, DNA Repair, Aging, and Neurodegeneration S Maynard, EF Fang, M Scheibye-Knudsen, DL Croteau, VA Bohr Cold Spring Harbor perspectives in medicine 5 (10), a025130, 2015 | 157 | 2015 |
| Proteins with antifungal properties and other medicinal applications from plants and mushrooms JH Wong, TB Ng, RCF Cheung, XJ Ye, HX Wang, SK Lam, P Lin, ... Applied microbiology and biotechnology 87 (4), 1221-1235, 2010 | 148 | 2010 |
| NAD+ in aging: molecular mechanisms and translational implications EF Fang, S Lautrup, Y Hou, TG Demarest, DL Croteau, MP Mattson, ... Trends in molecular medicine 23 (10), 899-916, 2017 | 146 | 2017 |
| A research agenda for aging in China in the 21st century EF Fang, M Scheibye-Knudsen, HJ Jahn, J Li, L Ling, H Guo, X Zhu, ... Ageing research reviews 24, 197-205, 2015 | 145 | 2015 |
| Mitophagy in neurodegeneration and aging EM Fivenson, S Lautrup, N Sun, M Scheibye-Knudsen, T Stevnsner, ... Neurochemistry international 109, 202-209, 2017 | 139 | 2017 |
| Ribonucleases of different origins with a wide spectrum of medicinal applications EF Fang, TB Ng Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1815 (1), 65-74, 2011 | 127 | 2011 |
| Nicotinamide improves aspects of healthspan, but not lifespan, in mice SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ... Cell metabolism 27 (3), 667-676. e4, 2018 | 106 | 2018 |
| The MAP30 protein from bitter gourd (Momordica charantia) seeds promotes apoptosis in liver cancer cells in vitro and in vivo EF Fang, CZY Zhang, JH Wong, JY Shen, CH Li, TB Ng Cancer letters 324 (1), 66-74, 2012 | 97 | 2012 |
| Momordica Charantia lectin, a type II ribosome inactivating protein, exhibits antitumor activity toward human nasopharyngeal carcinoma cells in vitro and in vivo EF Fang, CZY Zhang, TB Ng, JH Wong, WL Pan, XJ Ye, YS Chan, ... Cancer Prevention Research 5 (1), 109-121, 2012 | 91 | 2012 |
| DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes P Sykora, M Misiak, Y Wang, S Ghosh, GS Leandro, D Liu, J Tian, ... Nucleic acids research 43 (2), 943-959, 2015 | 78 | 2015 |
| A Lectin with Anti-HIV-1 Reverse Transcriptase, Antitumor, and Nitric Oxide Inducing Activities from Seeds of Phaseolus vulgaris cv. Extralong Autumn Purple Bean EF Fang, P Lin, JH Wong, SW Tsao, TB Ng Journal of agricultural and food chemistry 58 (4), 2221-2229, 2010 | 77 | 2010 |
| Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis EF Fang, CZY Zhang, L Zhang, JH Wong, YS Chan, WL Pan, XL Dan, ... PLoS One 7 (9), e41592, 2012 | 65 | 2012 |
Morten Scheibye-KnudsenCenter for Healthy Aging, University of CopenhagenVerified email at sund.ku.dk
