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Rohit V. Pappu
Rohit V. Pappu
Gene K. Beare Distinguished Professor of Biomedical Engineering, Washington University in St. Louis
Verified email at wustl.edu - Homepage
Title
Cited by
Cited by
Year
Classification of intrinsically disordered regions and proteins
R Van Der Lee, M Buljan, B Lang, RJ Weatheritt, GW Daughdrill, ...
Chemical reviews 114 (13), 6589-6631, 2014
21532014
Coexisting liquid phases underlie nucleolar subcompartments
M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ...
Cell 165 (7), 1686-1697, 2016
17712016
A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins
J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang, M Jahnel, ...
Cell 174 (3), 688-699. e16, 2018
16702018
Polymer physics of intracellular phase transitions
CP Brangwynne, P Tompa, RV Pappu
Nature Physics 11 (11), 899-904, 2015
14332015
Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
RK Das, RV Pappu
Proceedings of the National Academy of Sciences 110 (33), 13392-13397, 2013
9362013
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
EW Martin, AS Holehouse, I Peran, M Farag, JJ Incicco, A Bremer, ...
Science 367 (6478), 694-699, 2020
8012020
Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein
CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ...
Molecular cell 63 (1), 72-85, 2016
7432016
RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation
J Guillén-Boixet, A Kopach, AS Holehouse, S Wittmann, M Jahnel, ...
Cell 181 (2), 346-361. e17, 2020
6752020
Physical principles underlying the complex biology of intracellular phase transitions
JM Choi, AS Holehouse, RV Pappu
Annual review of biophysics 49 (1), 107-133, 2020
6732020
Phase separation of a yeast prion protein promotes cellular fitness
TM Franzmann, M Jahnel, A Pozniakovsky, J Mahamid, AS Holehouse, ...
Science 359 (6371), eaao5654, 2018
6652018
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
6042017
Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
AH Mao, SL Crick, A Vitalis, CL Chicoine, RV Pappu
Proceedings of the National Academy of Sciences 107 (18), 8183-8188, 2010
6042010
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
MT Wei, S Elbaum-Garfinkle, AS Holehouse, CCH Chen, M Feric, ...
Nature chemistry 9 (11), 1118-1125, 2017
5162017
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
X Hu, SL Crick, G Bu, C Frieden, RV Pappu, JM Lee
Proceedings of the National Academy of Sciences 106 (48), 20324-20329, 2009
4872009
AlphaFold and implications for intrinsically disordered proteins
KM Ruff, RV Pappu
Journal of molecular biology 433 (20), 167208, 2021
4552021
CIDER: resources to analyze sequence-ensemble relationships of intrinsically disordered proteins
AS Holehouse, RK Das, JN Ahad, MOG Richardson, RV Pappu
Biophysical journal 112 (1), 16-21, 2017
4472017
Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties
S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ...
Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019
4132019
Relating sequence encoded information to form and function of intrinsically disordered proteins
RK Das, KM Ruff, RV Pappu
Current opinion in structural biology 32, 102-112, 2015
4042015
The Flory isolated-pair hypothesis is not valid for polypeptide chains: implications for protein folding
RV Pappu, R Srinivasan, GD Rose
Proceedings of the National Academy of Sciences 97 (23), 12565-12570, 2000
3672000
A conceptual framework for understanding phase separation and addressing open questions and challenges
T Mittag, RV Pappu
Molecular cell 82 (12), 2201-2214, 2022
3542022
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