ASPIRE registry: assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre J Hurdman, R Condliffe, CA Elliot, C Davies, C Hill, JM Wild, D Capener, ... European Respiratory Journal 39 (4), 945-955, 2012 | 521 | 2012 |
Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses I Sabroe, EC Jones, LR Usher, MKB Whyte, SK Dower The Journal of Immunology 168 (9), 4701-4710, 2002 | 500 | 2002 |
Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span I Sabroe, LR Prince, EC Jones, MJ Horsburgh, SJ Foster, SN Vogel, ... The Journal of Immunology 170 (10), 5268-5275, 2003 | 478 | 2003 |
Toll-like receptors in health and disease: complex questions remain I Sabroe, RC Read, MKB Whyte, DH Dockrell, SN Vogel, SK Dower The journal of immunology 171 (4), 1630-1635, 2003 | 337 | 2003 |
The role of TLRs in neutrophil activation LR Prince, MK Whyte, I Sabroe, LC Parker Current opinion in pharmacology 11 (4), 397-403, 2011 | 307 | 2011 |
The role of TLR activation in inflammation I Sabroe, LC Parker, SK Dower, MKB Whyte The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 299 | 2008 |
Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity LC Parker, LR Prince, I Sabroe Clinical & Experimental Immunology 147 (2), 199-207, 2007 | 297 | 2007 |
Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early-and late-phase allergic reactions … A Menzies-Gow, S Ying, I Sabroe, VL Stubbs, D Soler, TJ Williams, ... The Journal of Immunology 169 (5), 2712-2718, 2002 | 295 | 2002 |
Pulmonary hypertension in COPD: results from the ASPIRE registry J Hurdman, R Condliffe, CA Elliot, A Swift, S Rajaram, C Davies, C Hill, ... European Respiratory Journal 41 (6), 1292-1301, 2013 | 287 | 2013 |
Invited review: Tolerance to microbial TLR ligands: Molecular mechanisms and relevance to disease AE Medvedev, I Sabroe, JD Hasday, SN Vogel Journal of endotoxin research 12 (3), 133-150, 2006 | 280 | 2006 |
A small molecule antagonist of chemokine receptors CCR1 and CCR3: potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry I Sabroe, MJ Peck, BJ Van Keulen, A Jorritsma, G Simmons, PR Clapham, ... Journal of Biological Chemistry 275 (34), 25985-25992, 2000 | 274 | 2000 |
The role of Toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis I Sabroe, SK Dower, MKB Whyte Clinical infectious diseases 41 (Supplement_7), S421-S426, 2005 | 272 | 2005 |
The expression and roles of Toll-like receptors in the biology of the human neutrophil LC Parker, MKB Whyte, SK Dower, I Sabroe Journal of leukocyte biology 77 (6), 886-892, 2005 | 263 | 2005 |
The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy JE Pease, I Sabroe American Journal of Respiratory Medicine 1, 19-25, 2002 | 263 | 2002 |
Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways I Sabroe, A Hartnell, LA Jopling, S Bel, PD Ponath, JE Pease, PD Collins, ... The Journal of Immunology 162 (5), 2946-2955, 1999 | 219 | 1999 |
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice SR Walmsley, ER Chilvers, AA Thompson, K Vaughan, HM Marriott, ... The Journal of clinical investigation 121 (3), 1053-1063, 2011 | 212 | 2011 |
Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo FJ Culley, A Brown, DM Conroy, I Sabroe, DI Pritchard, TJ Williams The Journal of Immunology 165 (11), 6447-6453, 2000 | 183 | 2000 |
Agonists of toll-like receptor (TLR) 2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor JR Ward, L Bingle, HM Judge, SB Brown, RF Storey, MKB Whyte, ... Thrombosis and haemostasis 94 (10), 831-838, 2005 | 181 | 2005 |
Toll-like receptor (TLR) 2 and TLR4 agonists regulate CCR expression in human monocytic cells LC Parker, MKB Whyte, SN Vogel, SK Dower, I Sabroe The Journal of Immunology 172 (8), 4977-4986, 2004 | 180 | 2004 |
Pulmonary hypertension: diagnosis and management DG Kiely, CA Elliot, I Sabroe, R Condliffe Bmj 346, 2013 | 171 | 2013 |