|Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses|
I Sabroe, EC Jones, LR Usher, MKB Whyte, SK Dower
The Journal of Immunology 168 (9), 4701-4710, 2002
|Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span|
I Sabroe, LR Prince, EC Jones, MJ Horsburgh, SJ Foster, SN Vogel, ...
The Journal of Immunology 170 (10), 5268-5275, 2003
|Toll-like receptors in health and disease: complex questions remain|
I Sabroe, RC Read, MKB Whyte, DH Dockrell, SN Vogel, SK Dower
The journal of immunology 171 (4), 1630-1635, 2003
|ASPIRE registry: assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre|
J Hurdman, R Condliffe, CA Elliot, C Davies, C Hill, JM Wild, D Capener, ...
European Respiratory Journal 39 (4), 945-955, 2012
|Translational mini‐review series on Toll‐like receptors: networks regulated by Toll‐like receptors mediate innate and adaptive immunity|
LC Parker, LR Prince, I Sabroe
Clinical & Experimental Immunology 147 (2), 199-207, 2007
|A small molecule antagonist of chemokine receptors CCR1 and CCR3 potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry|
I Sabroe, MJ Peck, BJ Van Keulen, A Jorritsma, G Simmons, PR Clapham, ...
Journal of Biological Chemistry 275 (34), 25985-25992, 2000
|Invited review: tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease|
AE Medvedev, I Sabroe, JD Hasday, SN Vogel
Journal of endotoxin research 12 (3), 133-150, 2006
|The expression and roles of Toll‐like receptors in the biology of the human neutrophil|
LC Parker, MKB Whyte, SK Dower, I Sabroe
Journal of leukocyte biology 77 (6), 886-892, 2005
|The role of TLR activation in inflammation|
I Sabroe, LC Parker, SK Dower, MKB Whyte
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008
|Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways|
I Sabroe, A Hartnell, LA Jopling, S Bel, PD Ponath, JE Pease, PD Collins, ...
The Journal of Immunology 162 (5), 2946-2955, 1999
|The role of Toll-like receptors in the regulation of neutrophil migration, activation, and apoptosis|
I Sabroe, SK Dower, MKB Whyte
Clinical infectious diseases 41 (Supplement_7), S421-S426, 2005
|Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early-and late-phase allergic reactions …|
A Menzies-Gow, S Ying, I Sabroe, VL Stubbs, D Soler, TJ Williams, ...
The Journal of Immunology 169 (5), 2712-2718, 2002
|The role of interleukin-8 and its receptors in inflammatory lung disease|
JE Pease, I Sabroe
American Journal of Respiratory Medicine 1 (1), 19-25, 2002
|The role of TLRs in neutrophil activation|
LR Prince, MK Whyte, I Sabroe, LC Parker
Current opinion in pharmacology 11 (4), 397-403, 2011
|Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo|
FJ Culley, A Brown, DM Conroy, I Sabroe, DI Pritchard, TJ Williams
The Journal of Immunology 165 (11), 6447-6453, 2000
|Pulmonary hypertension in COPD: results from the ASPIRE registry|
J Hurdman, R Condliffe, CA Elliot, A Swift, S Rajaram, C Davies, C Hill, ...
European Respiratory Journal 41 (6), 1292-1301, 2013
|Agonists of toll-like receptor (TLR) 2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor|
JR Ward, L Bingle, HM Judge, SB Brown, RF Storey, MKB Whyte, ...
Thrombosis and haemostasis 94 (10), 831-838, 2005
|Toll-like receptor (TLR) 2 and TLR4 agonists regulate CCR expression in human monocytic cells|
LC Parker, MKB Whyte, SN Vogel, SK Dower, I Sabroe
The Journal of Immunology 172 (8), 4977-4986, 2004
|Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice|
SR Walmsley, ER Chilvers, AA Thompson, K Vaughan, HM Marriott, ...
The Journal of clinical investigation 121 (3), 1053-1063, 2011
|δ12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis|
A Heinemann, R Schuligoi, I Sabroe, A Hartnell, BA Peskar
The Journal of Immunology 170 (9), 4752-4758, 2003