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Gavin Whitlock
Gavin Whitlock
Sandexis
Verified email at sandexis.co.uk
Title
Cited by
Cited by
Year
Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space
A Alex, DS Millan, M Perez, F Wakenhut, GA Whitlock
MedChemComm 2 (7), 669-674, 2011
2352011
Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform
B Desai, K Dixon, E Farrant, Q Feng, KR Gibson, WP van Hoorn, J Mills, ...
Journal of medicinal chemistry 56 (7), 3033-3047, 2013
1202013
Catalytic asymmetric hydroboration with heterotopic PN ligands: Trends in enantioselectivity with increased steric demand
JM Valk, GA Whitlock, TP Layzell, JM Brown
Tetrahedron: Asymmetry 6 (10), 2593-2596, 1995
1151995
Enantioselective Synthesis of ent-Stellettamide A via a Novel Dipolar Cycloaddition Reaction of (Trimethylsilyl) diazomethane.
GA Whitlock, EM Carreira
The Journal of Organic Chemistry 62 (23), 7916-7917, 1997
731997
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase
PV Fish, GA Allan, S Bailey, J Blagg, R Butt, MG Collis, D Greiling, ...
Journal of medicinal chemistry 50 (15), 3442-3456, 2007
652007
Asymmetric synthesis of cyclic ethers by rearrangement of oxonium ylides generated from chiral copper carbenoids
JS Clark, M Fretwell, GA Whitlock, CJ Burns, DNA Fox
Tetrahedron letters 39 (1-2), 97-100, 1998
651998
A short synthesis of (±)-decarestrictine L
JS Clark, GA Whitlock
Tetrahedron letters 35 (34), 6381-6382, 1994
621994
Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity
CE Mowbray, S Braillard, W Speed, PA Glossop, GA Whitlock, KR Gibson, ...
Journal of medicinal chemistry 58 (24), 9615-9624, 2015
602015
A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L
JS Clark, TC Fessard, GA Whitlock
Tetrahedron 62 (1), 73-78, 2006
602006
Derivatives of (3S)-N-(biphenyl-2-ylmethyl) pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor …
PV Fish, NS Barta, DLF Gray, T Ryckmans, A Stobie, F Wakenhut, ...
Bioorganic & medicinal chemistry letters 18 (15), 4355-4359, 2008
582008
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
562003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
562003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
562003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
562003
Chloroquine–astemizole hybrids with potent in vitro and in vivo antiplasmodial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & medicinal chemistry letters 19 (2), 481-484, 2009
542009
Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & medicinal chemistry letters 19 (2), 401-405, 2009
512009
Enantioselective Synthesis of ent‐Stellettamide A: Asymmetric Dipolar Cycloadditions with Me3SiCHN2
GA Whitlock, EM Carreira
Helvetica chimica acta 83 (8), 2007-2022, 2000
472000
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
PV Fish, C Deur, X Gan, K Greene, D Hoople, M Mackenny, KS Para, ...
Bioorganic & medicinal chemistry letters 18 (8), 2562-2566, 2008
432008
Design and synthesis of a pan-Janus kinase inhibitor clinical candidate (PF-06263276) suitable for inhaled and topical delivery for the treatment of inflammatory diseases of …
P Jones, RI Storer, YA Sabnis, FM Wakenhut, GA Whitlock, KS England, ...
Journal of Medicinal Chemistry 60 (2), 767-786, 2017
422017
Compounds
PV Fish, MJ Fray, A Stobie, F Wakenhut, GA Whitlock, MD Andrews, ...
US Patent 7,378,436, 2008
382008
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