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Gavin Whitlock
Gavin Whitlock
Sandexis
Verified email at sandexis.co.uk
Title
Cited by
Cited by
Year
Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space
A Alex, DS Millan, M Perez, F Wakenhut, GA Whitlock
MedChemComm 2 (7), 669-674, 2011
3142011
Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform
B Desai, K Dixon, E Farrant, Q Feng, KR Gibson, WP van Hoorn, J Mills, ...
Journal of medicinal chemistry 56 (7), 3033-3047, 2013
1552013
Catalytic asymmetric hydroboration with heterotopic PN ligands: Trends in enantioselectivity with increased steric demand
JM Valk, GA Whitlock, TP Layzell, JM Brown
Tetrahedron: Asymmetry 6 (10), 2593-2596, 1995
1261995
Enantioselective Synthesis of ent-Stellettamide A via a Novel Dipolar Cycloaddition Reaction of (Trimethylsilyl) diazomethane.
GA Whitlock, EM Carreira
The Journal of Organic Chemistry 62 (23), 7916-7917, 1997
761997
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase
PV Fish, GA Allan, S Bailey, J Blagg, R Butt, MG Collis, D Greiling, ...
Journal of medicinal chemistry 50 (15), 3442-3456, 2007
732007
Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity
CE Mowbray, S Braillard, W Speed, PA Glossop, GA Whitlock, KR Gibson, ...
Journal of medicinal chemistry 58 (24), 9615-9624, 2015
712015
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
692003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
692003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
692003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
692003
Asymmetric synthesis of cyclic ethers by rearrangement of oxonium ylides generated from chiral copper carbenoids
JS Clark, M Fretwell, GA Whitlock, CJ Burns, DNA Fox
Tetrahedron letters 39 (1-2), 97-100, 1998
681998
A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L
JS Clark, TC Fessard, GA Whitlock
Tetrahedron 62 (1), 73-78, 2006
612006
A short synthesis of (±)-decarestrictine L
JS Clark, GA Whitlock
Tetrahedron letters 35 (34), 6381-6382, 1994
611994
Chloroquine–astemizole hybrids with potent in vitro and in vivo antiplasmodial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & medicinal chemistry letters 19 (2), 481-484, 2009
572009
Quantitative chemical proteomic profiling of ubiquitin specific proteases in intact cancer cells
JA Ward, L McLellan, M Stockley, KR Gibson, GA Whitlock, C Knights, ...
ACS chemical biology 11 (12), 3268-3272, 2016
552016
Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & medicinal chemistry letters 19 (2), 401-405, 2009
532009
Design and synthesis of a pan-Janus kinase inhibitor clinical candidate (PF-06263276) suitable for inhaled and topical delivery for the treatment of inflammatory diseases of …
P Jones, RI Storer, YA Sabnis, FM Wakenhut, GA Whitlock, KS England, ...
Journal of Medicinal Chemistry 60 (2), 767-786, 2017
522017
Enantioselective Synthesis of ent‐Stellettamide A: Asymmetric Dipolar Cycloadditions with Me3SiCHN2
GA Whitlock, EM Carreira
Helvetica chimica acta 83 (8), 2007-2022, 2000
462000
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
PV Fish, C Deur, X Gan, K Greene, D Hoople, M Mackenny, KS Para, ...
Bioorganic & medicinal chemistry letters 18 (8), 2562-2566, 2008
442008
Pyrazolopyridines and pyrazolopyrimidines
JW Coe, CM Dehnhardt, P Jones, YA Sabnis, JW Strohbach, ...
US Patent 9,518,052, 2016
432016
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