Gavin Whitlock
Gavin Whitlock
Sandexis
Verified email at sandexis.co.uk
Title
Cited by
Cited by
Year
Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space
A Alex, DS Millan, M Perez, F Wakenhut, GA Whitlock
MedChemComm 2 (7), 669-674, 2011
1972011
Catalytic asymmetric hydroboration with heterotopic PN ligands: Trends in enantioselectivity with increased steric demand
JM Valk, GA Whitlock, TP Layzell, JM Brown
Tetrahedron: Asymmetry 6 (10), 2593-2596, 1995
1051995
Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform
B Desai, K Dixon, E Farrant, Q Feng, KR Gibson, WP van Hoorn, J Mills, ...
Journal of medicinal chemistry 56 (7), 3033-3047, 2013
972013
Enantioselective Synthesis of ent-Stellettamide A via a Novel Dipolar Cycloaddition Reaction of (Trimethylsilyl)diazomethane
GA Whitlock, EM Carreira
The Journal of organic chemistry 62 (23), 7916-7917, 1997
671997
A short synthesis of ()-decarestrictine L
JS Clark, GA Whitlock
Tetrahedron letters 35 (34), 6381-6382, 1994
601994
Asymmetric synthesis of cyclic ethers by rearrangement of oxonium ylides generated from chiral copper carbenoids
JS Clark, M Fretwell, GA Whitlock, CJ Burns, DNA Fox
Tetrahedron letters 39 (1-2), 97-100, 1998
591998
A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L
JS Clark, TC Fessard, GA Whitlock
Tetrahedron 62 (1), 73-78, 2006
572006
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase
PV Fish, GA Allan, S Bailey, J Blagg, R Butt, MG Collis, D Greiling, ...
Journal of medicinal chemistry 50 (15), 3442-3456, 2007
522007
Chloroquine–astemizole hybrids with potent in vitro and in vivo antiplasmodial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & medicinal chemistry letters 19 (2), 481-484, 2009
482009
Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity
CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser
Bioorganic & Medicinal Chemistry Letters 19 (2), 401-405, 2009
462009
Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity
CE Mowbray, S Braillard, W Speed, PA Glossop, GA Whitlock, KR Gibson, ...
Journal of medicinal chemistry 58 (24), 9615-9624, 2015
452015
Enantioselective Synthesis of ent‐Stellettamide A: Asymmetric Dipolar Cycloadditions with Me3SiCHN2
GA Whitlock, EM Carreira
Helvetica chimica acta 83 (8), 2007-2022, 2000
452000
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
PV Fish, C Deur, X Gan, K Greene, D Hoople, M Mackenny, KS Para, ...
Bioorganic & medicinal chemistry letters 18 (8), 2562-2566, 2008
422008
Compounds
PV Fish, MJ Fray, A Stobie, F Wakenhut, GA Whitlock, MD Andrews, ...
US Patent 7,378,436, 2008
362008
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
362003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
362003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
362003
Metalloprotease inhibitors
KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson
US Patent 6,511,993, 2003
362003
Pyridyl-phenyl ether monoamine reuptake inhibitors: impact of lipophilicity on dual SNRI pharmacology and off-target promiscuity
GA Whitlock, PV Fish, MJ Fray, A Stobie, F Wakenhut
Bioorganic & medicinal chemistry letters 18 (9), 2896-2899, 2008
292008
1-(2-Phenoxyphenyl) methanamines: SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinity
GA Whitlock, J Blagg, PV Fish
Bioorganic & medicinal chemistry letters 18 (2), 596-599, 2008
292008
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