Jeffrey M. Spraggins
Jeffrey M. Spraggins
Assistant Professor, Department of Cell & Developmental Biology at Vanderbilt University
Verified email at
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Cited by
MALDI imaging of lipid biochemistry in tissues by mass spectrometry
KA Zemski Berry, JA Hankin, RM Barkley, JM Spraggins, RM Caprioli, ...
Chemical reviews 111 (10), 6491-6512, 2011
Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping
R Van de Plas, J Yang, J Spraggins, RM Caprioli
Nature methods 12 (4), 366-372, 2015
The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ...
Nature 574 (7777), 187-192, 2019
Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry
PM Angel, JM Spraggins, HS Baldwin, R Caprioli
Analytical chemistry 84 (3), 1557-1564, 2012
Non‐small cell lung cancer is characterized by dramatic changes in phospholipid profiles
E Marien, M Meister, T Muley, S Fieuws, S Bordel, R Derua, J Spraggins, ...
International Journal of Cancer 137 (7), 1539-1548, 2015
High-speed MALDI-TOF imaging mass spectrometry: rapid ion image acquisition and considerations for next generation instrumentation
JM Spraggins, RM Caprioli
Journal of the American Society for mass Spectrometry 22 (6), 1022-1031, 2011
Next‐generation technologies for spatial proteomics: integrating ultra‐high speed MALDI‐TOF and high mass resolution MALDI FTICR imaging mass spectrometry for protein analysis
JM Spraggins, DG Rizzo, JL Moore, MJ Noto, EP Skaar, RM Caprioli
Proteomics 16 (11-12), 1678-1689, 2016
MALDI FTICR IMS of intact proteins: using mass accuracy to link protein images with proteomics data
JM Spraggins, DG Rizzo, JL Moore, KL Rose, ND Hammer, EP Skaar, ...
Journal of the American Society for Mass Spectrometry 26 (6), 974-985, 2015
High-performance molecular imaging with MALDI trapped ion-mobility time-of-flight (timsTOF) mass spectrometry
JM Spraggins, KV Djambazova, ES Rivera, LG Migas, EK Neumann, ...
Analytical chemistry 91 (22), 14552-14560, 2019
High resolution MALDI imaging mass spectrometry of retinal tissue lipids
DMG Anderson, Z Ablonczy, Y Koutalos, J Spraggins, RK Crouch, ...
Journal of the American Society for Mass Spectrometry 25 (8), 1394-1403, 2014
Protein identification strategies in MALDI imaging mass spectrometry: a brief review
DJ Ryan, JM Spraggins, RM Caprioli
Current opinion in chemical biology 48, 64-72, 2019
Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles1 [S]
KJ Grove, PA Voziyan, JM Spraggins, S Wang, P Paueksakon, RC Harris, ...
Journal of lipid research 55 (7), 1375-1385, 2014
A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry
ML Manier, JM Spraggins, ML Reyzer, JL Norris, RM Caprioli
Journal of Mass Spectrometry 49 (8), 665-673, 2014
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
T Manzo, BM Prentice, KG Anderson, A Raman, A Schalck, GS Codreanu, ...
Journal of Experimental Medicine 217 (8), 2020
Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions
JE Cassat, JL Moore, KJ Wilson, Z Stark, BM Prentice, R Van de Plas, ...
Science translational medicine 10 (432), eaan6361, 2018
Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma
E Marien, M Meister, T Muley, TG Del Pulgar, R Derua, JM Spraggins, ...
Oncotarget 7 (11), 12582, 2016
Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host
WJ Perry, JM Spraggins, JR Sheldon, CM Grunenwald, DE Heinrichs, ...
Proceedings of the National Academy of Sciences 116 (44), 21980-21982, 2019
The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry
Z Ablonczy, N Smith, DM Anderson, AC Grey, J Spraggins, Y Koutalos, ...
Proteomics 14 (7-8), 936-944, 2014
High-resolution matrix-assisted laser desorption ionization–imaging mass spectrometry of lipids in rodent optic nerve tissue
DMG Anderson, D Mills, J Spraggins, WS Lambert, DJ Calkins, KL Schey
Molecular vision 19, 581, 2013
MicroLESA: Integrating autofluorescence microscopy, in situ micro-digestions, and liquid extraction surface analysis for high spatial resolution targeted proteomic studies
DJ Ryan, NH Patterson, NE Putnam, AD Wilde, A Weiss, WJ Perry, ...
Analytical chemistry 91 (12), 7578-7585, 2019
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