Molecular basis for specificity of nuclear import and prediction of nuclear localization M Marfori, A Mynott, JJ Ellis, AM Mehdi, NFW Saunders, PM Curmi, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (9), 1562-1577, 2011 | 489 | 2011 |
Structural biology and regulation of protein import into the nucleus M Christie, CW Chang, G Róna, KM Smith, AG Stewart, AAS Takeda, ... Journal of molecular biology 428 (10), 2060-2090, 2016 | 252 | 2016 |
Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins M Christie, A Boland, E Huntzinger, O Weichenrieder, E Izaurralde Molecular cell 51 (3), 360-373, 2013 | 125 | 2013 |
Structural Basis of High‐Affinity Nuclear Localization Signal Interactions with Importin‐α M Marfori, TG Lonhienne, JK Forwood, B Kobe Traffic 13 (4), 532-548, 2012 | 113 | 2012 |
Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures JK Forwood, A Lange, U Zachariae, M Marfori, C Preast, H Grubmüller, ... Structure 18 (9), 1171-1183, 2010 | 109 | 2010 |
Crystallography and protein–protein interactions: biological interfaces and crystal contacts B Kobe, G Guncar, R Buchholz, T Huber, B Maco, N Cowieson, JL Martin, ... Biochemical Society Transactions 36 (6), 1438-1441, 2008 | 88 | 2008 |
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation JK Forwood, AS Thakur, G Guncar, M Marfori, D Mouradov, W Meng, ... Proceedings of the National Academy of Sciences 104 (25), 10382-10387, 2007 | 84 | 2007 |
Fully human VH single domains that rival the stability and cleft recognition of camelid antibodies R Rouet, K Dudgeon, M Christie, D Langley, D Christ Journal of Biological Chemistry 290 (19), 11905-11917, 2015 | 62 | 2015 |
An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay S Jonas, M Christie, D Peter, D Bhandari, B Loh, E Huntzinger, ... Nature structural & molecular biology 21 (7), 599-608, 2014 | 56 | 2014 |
Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP M Sobti, R Ishmukhametov, JC Bouwer, A Ayer, C Suarna, NJ Smith, ... eLife 8, e43864, 2019 | 48 | 2019 |
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights G Róna, M Marfori, M Borsos, I Scheer, E Takács, J Tóth, F Babos, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2495-2505, 2013 | 46 | 2013 |
Importin-β Is a GDP-to-GTP Exchange Factor of Ran IMPLICATIONS FOR THE MECHANISM OF NUCLEAR IMPORT TG Lonhienne, JK Forwood, M Marfori, G Robin, B Kobe, BJ Carroll Journal of Biological Chemistry 284 (34), 22549-22558, 2009 | 43 | 2009 |
Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display A Norman, C Franck, M Christie, PME Hawkins, K Patel, AS Ashhurst, ... ACS central science 7 (6), 1001-1008, 2021 | 41 | 2021 |
Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics JK Forwood, TG Lonhienne, M Marfori, G Robin, W Meng, G Guncar, ... Journal of molecular biology 383 (4), 772-782, 2008 | 36 | 2008 |
Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20 N Roman, M Christie, CMD Swarbrick, B Kobe, JK Forwood | 30 | 2013 |
Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation G Róna, M Borsos, JJ Ellis, AM Mehdi, M Christie, Z Környei, M Neubrandt, ... Cell Cycle 13 (22), 3551-3564, 2014 | 25 | 2014 |
eIF4E‐homologous protein (4EHP): a multifarious cap‐binding protein M Christie, C Igreja The FEBS Journal 290 (2), 266-285, 2023 | 24 | 2023 |
Ligand-induced conformational changes within a hexameric Acyl-CoA thioesterase M Marfori, B Kobe, JK Forwood Journal of Biological Chemistry 286 (41), 35643-35649, 2011 | 13 | 2011 |
Structural reconstruction of protein ancestry R Rouet, DB Langley, P Schofield, M Christie, B Roome, BT Porebski, ... Proceedings of the National Academy of Sciences 114 (15), 3897-3902, 2017 | 11 | 2017 |
Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha. JJ Chaston, AG Stewart, M Christie PloS one 12 (8), e0183587, 2017 | 9 | 2017 |