Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps PRSTF the International Common Disease Alliance Nature Medicine 27, 1876–1884, 2021 | 159* | 2021 |
The function of communities in protein interaction networks at multiple scales ACF Lewis, NS Jones, MA Porter, CM Deane BMC systems biology 4, 1-14, 2010 | 126 | 2010 |
Getting genetic ancestry right for science and society ACF Lewis, SJ Molina, PS Appelbaum, B Dauda, A Di Rienzo, A Fuentes, ... Science 376 (6590), 250-252, 2022 | 112 | 2022 |
Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues ACF Lewis, RC Green Genome Medicine 13 (1), 14, 2021 | 112 | 2021 |
Self-assembly and evolution of homomeric protein complexes G Villar, AW Wilber, AJ Williamson, P Thiara, JPK Doye, AA Louis, ... Physical review letters 102 (11), 118106, 2009 | 88 | 2009 |
Monodisperse self-assembly in a model with protein-like interactions AW Wilber, JPK Doye, AA Louis, ACF Lewis The Journal of chemical physics 131 (17), 2009 | 81 | 2009 |
Development of a clinical polygenic risk score assay and reporting workflow L Hao, P Kraft, GF Berriz, ED Hynes, C Koch, P Korategere V Kumar, ... Nature medicine 28 (5), 1006-1013, 2022 | 80 | 2022 |
Predicting protein–protein interactions in the context of protein evolution ACF Lewis, R Saeed, CM Deane Molecular BioSystems 6 (1), 55-64, 2010 | 69 | 2010 |
What evidence is there for the homology of protein-protein interactions? ACF Lewis, NS Jones, MA Porter, CM Deane Public Library of Science 8 (9), e1002645, 2012 | 53 | 2012 |
CRISPR-Cas9 and the non-germline non-controversy S Polcz, A Lewis Journal of Law and the Biosciences 3 (2), 413-425, 2016 | 48 | 2016 |
Polygenic risk scores in the clinic: translating risk into action ACF Lewis, RC Green, JL Vassy Human Genetics and Genomics Advances 2 (4), 2021 | 40 | 2021 |
Returning integrated genomic risk and clinical recommendations: The eMERGE study JE Linder, A Allworth, HT Bland, PJ Caraballo, RL Chisholm, EW Clayton, ... Genetics in Medicine 25 (4), 100006, 2023 | 38 | 2023 |
An international policy on returning genomic research results ACF Lewis, BM Knoppers, RC Green Genome Medicine 13, 1-3, 2021 | 29 | 2021 |
A scoping review of guidelines for the use of race, ethnicity, and ancestry reveals widespread consensus but also points of ongoing disagreement M Mauro, DS Allen, B Dauda, SJ Molina, BM Neale, ACF Lewis The American Journal of Human Genetics 109 (12), 2110-2125, 2022 | 14 | 2022 |
Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization ACF Lewis, EF Perez, AER Prince, HR Flaxman, L Gomez, DG Brockman, ... Genome Medicine 14 (1), 114, 2022 | 14 | 2022 |
Ancestry: How researchers use it and what they mean by it B Dauda, SJ Molina, DS Allen, A Fuentes, N Ghosh, M Mauro, BM Neale, ... Frontiers in Genetics 14, 1044555, 2023 | 13 | 2023 |
Polygenic Risk Score Task Force of the International Common Disease Alliance (2021) Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps A Adeyemo, MK Balaconis, DR Darnes, S Fatumo, P Granados Moreno, ... Nat Med 27 (11), 1876-1884, 0 | 11 | |
Where bioethics meets machine ethics ACF Lewis The American Journal of Bioethics 20 (11), 22-24, 2020 | 9 | 2020 |
The problems with patchwork: State approaches to regulating insurer use of genetic information JO Anderson, ACF Lewis, AER Prince DePaul J. Health Care L. 22, 1, 2021 | 8 | 2021 |
Long-awaited progress in addressing genetic discrimination in the United States ACF Lewis, RC Green, AER Prince Genetics in Medicine 23 (3), 429-431, 2021 | 6 | 2021 |