Pr Philippe Compain
Pr Philippe Compain
Professor of Organic Chemistry, Strasbourg University
Verified email at unistra.fr - Homepage
TitleCited byYear
Iminosugars: From synthesis to therapeutic applications
P Compain, OR Martin
John Wiley & Sons, 2007
4692007
Carbohydrate mimetics-based glycosyltransferase inhibitors
P Compain, OR Martin
Bioorganic & medicinal chemistry 9 (12), 3077-3092, 2001
3872001
Design, synthesis and biological evaluation of iminosugar-based glycosyltransferase inhibitors
P Compain, OR Martin
Current topics in medicinal chemistry 3 (5), 541-560, 2003
2172003
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect
P Compain, C Decroocq, J Iehl, M Holler, D Hazelard, T Mena Barragan, ...
Angewandte Chemie International Edition 49 (33), 5753-5756, 2010
1762010
Olefin Metathesis of Amine‐Containing Systems: Beyond the Current Consensus
P Compain
Advanced Synthesis & Catalysis 349 (11‐12), 1829-1846, 2007
1722007
Design and synthesis of highly potent and selective pharmacological chaperones for the treatment of Gaucher's disease
P Compain, OR Martin, C Boucheron, G Godin, L Yu, K Ikeda, N Asano
ChemBioChem 7 (9), 1356-1359, 2006
1702006
Tactics and strategies for the synthesis of iminosugar C-glycosides: a review
P Compain, V Chagnault, OR Martin
Tetrahedron: Asymmetry 20 (6-8), 672-711, 2009
1422009
α-1-C-Octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease
L Yu, K Ikeda, A Kato, I Adachi, G Godin, P Compain, O Martin, N Asano
Bioorganic & medicinal chemistry 14 (23), 7736-7744, 2006
1132006
First total synthesis of (+)-hyacinthacine A2
L Rambaud, P Compain, OR Martin
Tetrahedron: Asymmetry 12 (13), 1807-1809, 2001
832001
The multivalent effect in glycosidase inhibition: probing the influence of architectural parameters with cyclodextrin‐based iminosugar click clusters
C Decroocq, D Rodríguez‐Lucena, V Russo, T Mena Barragán, ...
Chemistry–A European Journal 17 (49), 13825-13831, 2011
822011
The multivalent effect in glycosidase inhibition: A new, rapidly emerging topic in glycoscience
P Compain, A Bodlenner
ChemBioChem 15 (9), 1239-1251, 2014
752014
A general strategy for the practical synthesis of nojirimycin C-glycosides and analogues. Extension to the first reported example of an iminosugar 1-phosphonate
G Godin, P Compain, G Masson, OR Martin
The Journal of organic chemistry 67 (20), 6960-6970, 2002
722002
Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
C Bonduelle, J Huang, T Mena-Barragán, CO Mellet, C Decroocq, ...
Chemical Communications 50 (25), 3350-3352, 2014
642014
Second‐generation iminoxylitol‐based pharmacological chaperones for the treatment of Gaucher disease
F Oulaïdi, S Front‐Deschamps, E Gallienne, E Lesellier, K Ikeda, N Asano, ...
ChemMedChem 6 (2), 353-361, 2011
632011
Cyclodextrin‐Based Iminosugar Click Clusters: The First Examples of Multivalent Pharmacological Chaperones for the Treatment of Lysosomal Storage Disorders
C Decroocq, D Rodríguez‐Lucena, K Ikeda, N Asano, P Compain
ChemBioChem 13 (5), 661-664, 2012
602012
General access to iminosugar C-glycoside building blocks by means of cross-metathesis: a gateway to glycoconjugate mimetics
G Godin, P Compain, OR Martin
Organic letters 5 (18), 3269-3272, 2003
592003
New Aspects of Catalytic Intramolecular C− H Amination: Unexpected Formation of a Seven-Membered Ring in Nitrogen-Containing Systems
S Toumieux, P Compain, OR Martin, M Selkti
Organic letters 8 (20), 4493-4496, 2006
532006
Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: the search for new therapeutic agents against Gaucher disease
C Boucheron, V Desvergnes, P Compain, OR Martin, A Lavi, M Mackeen, ...
Tetrahedron: Asymmetry 16 (10), 1747-1756, 2005
512005
Reaction of the lithio-derivative of methoxy allene with SAMP-hydrazones: Access to enantiopure 3-pyrrolines
V Breuil-Desvergnes, P Compain, JM Vatèle, J Goré
Tetrahedron letters 40 (27), 5009-5012, 1999
481999
The multivalent effect in glycosidase inhibition: Probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin‐based iminosugar click clusters
C Decroocq, A Joosten, R Sergent, T Mena Barragan, C Ortiz Mellet, ...
ChemBioChem 14 (15), 2038-2049, 2013
452013
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