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Stephen H Pasternak
Stephen H Pasternak
Robarts Research Institute/ University of Western Ontario
Verified email at robarts.ca
Title
Cited by
Cited by
Year
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
RC Moore, IY Lee, GL Silverman, PM Harrison, R Strome, C Heinrich, ...
Journal of molecular biology 292 (4), 797-817, 1999
6941999
Presenilin-1, Nicastrin, Amyloid Precursor Protein, and g-Secretase Activity Are Co-localized in the Lysosomal Membrane.
SH Pasternak, RD Bagshaw, M Guiral, S Zhang, CA Ackerley, BJ Pak, ...
Journal of Biological Chemistry 278 (29), 26687-26694, 2003
3892003
The effects of oxytocin on social cognition and behaviour in frontotemporal dementia
S Jesso, D Morlog, S Ross, MD Pell, SH Pasternak, DGV Mitchell, ...
Brain 134 (9), 2493-2501, 2011
1612011
The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: reexamining the spatial paradox from a lysosomal perspective
SH Pasternak, JW Callahan, DJ Mahuran
Journal of Alzheimer's Disease 6 (1), 53-65, 2004
1542004
Four‐pool modeling of proton exchange processes in biological systems in the presence of MRI–paramagnetic chemical exchange saturation transfer (PARACEST) agents
AX Li, RHE Hudson, JW Barrett, CK Jones, SH Pasternak, R Bartha
Magnetic Resonance in Medicine: An Official Journal of the International …, 2008
1252008
Ambroxol as a novel disease-modifying treatment for Parkinson’s disease dementia: Protocol for a single-centre, randomized, double-blind, placebo-controlled trial
CRA Silveira, J MacKinley, K Coleman, Z Li, E Finger, R Bartha, ...
BMC neurology 19, 1-10, 2019
1192019
Oxytocin for frontotemporal dementia: a randomized dose-finding study of safety and tolerability
EC Finger, J MacKinley, M Blair, LD Oliver, S Jesso, MC Tartaglia, ...
Neurology 84 (2), 174-181, 2015
1012015
Amyloid and Alzheimer's disease: inside and out
JHK Tam, SH Pasternak
Canadian Journal of Neurological Sciences 39 (3), 286-298, 2012
952012
The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid
JHK Tam, C Seah, SH Pasternak
Molecular brain 7, 1-18, 2014
862014
Rapid and direct transport of cell surface APP to the lysosome defines a novel selective pathway
A Lorenzen, J Samosh, K Vandewark, PH Anborgh, C Seah, ...
Molecular brain 3, 1-13, 2010
812010
Oligomeric aggregates of amyloid β peptide 1–42 activate ERK/MAPK in SH-SY5Y cells via the α7 nicotinic receptor
KF Young, SH Pasternak, RJ Rylett
Neurochemistry international 55 (8), 796-801, 2009
612009
Depressive symptoms negatively impact Montreal Cognitive Assessment performance: a memory clinic experience
M Blair, K Coleman, S Jesso, VD Jodoin, K Smolewska, E Warriner, ...
Canadian Journal of Neurological Sciences 43 (4), 513-517, 2016
542016
Nicastrin is a resident lysosomal membrane protein
RD Bagshaw, SH Pasternak, DJ Mahuran, JW Callahan
Biochemical and biophysical research communications 300 (3), 615-618, 2003
542003
Vitamin E in aging persons with Down syndrome: A randomized, placebo-controlled clinical trial
M Sano, PS Aisen, HF Andrews, WY Tsai, F Lai, AJ Dalton, ...
Neurology 86 (22), 2071-2076, 2016
472016
A paramagnetic chemical exchange-based MRI probe metabolized by cathepsin D: design, synthesis and cellular uptake studies
M Suchý, R Ta, AX Li, F Wojciechowski, SH Pasternak, R Bartha, ...
Organic & Biomolecular Chemistry 8 (11), 2560-2566, 2010
442010
MIiSR: molecular interactions in super-resolution imaging enables the analysis of protein interactions, dynamics and formation of multi-protein structures
FA Caetano, BS Dirk, JHK Tam, PC Cavanagh, M Goiko, SSG Ferguson, ...
PLoS computational biology 11 (12), e1004634, 2015
432015
Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes
W Tang, JHK Tam, C Seah, J Chiu, A Tyrer, SP Cregan, SO Meakin, ...
Molecular brain 8, 1-21, 2015
422015
Reduced hippocampal glutamate and posterior cingulate N-acetyl aspartate in mild cognitive impairment and Alzheimer’s disease is associated with episodic memory performance and …
D Wong, S Atiya, J Fogarty, M Montero-Odasso, SH Pasternak, C Brymer, ...
Journal of Alzheimer's Disease 73 (4), 1385-1405, 2020
412020
Ontario neurodegenerative disease research initiative (ONDRI): structural MRI methods and outcome measures
J Ramirez, MF Holmes, CJM Scott, M Ozzoude, S Adamo, GM Szilagyi, ...
Frontiers in neurology 11, 847, 2020
332020
The ONDRISeq panel: custom-designed next-generation sequencing of genes related to neurodegeneration
SMK Farhan, AA Dilliott, M Ghani, C Sato, E Liang, M Zhang, AD McIntyre, ...
NPJ Genomic Medicine 1 (1), 1-11, 2016
312016
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