Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies AZ Abdel-Azeem, AA Abdel-Hafez, GS El-Karamany, HH Farag Bioorganic & medicinal chemistry 17 (10), 3665-3670, 2009 | 40 | 2009 |
Prospective protective effect of ellagic acid as a SIRT1 activator in iron oxide nanoparticle-induced renal damage in rats ET Mohammed, KS Hashem, AZ Abdelazem, FAMA Foda Biological trace element research 198 (1), 177-188, 2020 | 37 | 2020 |
Staurosporine analogues from microbial and synthetic sources and their biological activities B S Park, A Z Abdel-Azeem, M M Al-Sanea, K H Yoo, J S Tae, S H Lee Current Medicinal Chemistry 20 (31), 3872-3902, 2013 | 28 | 2013 |
Protective effects of hesperidin against MTX-induced hepatotoxicity in male albino rats RM Abdelaziz, AZ Abdelazem, KS Hashem, YA Attia Naunyn-Schmiedeberg's Archives of Pharmacology 393, 1405-1417, 2020 | 27 | 2020 |
Design, synthesis and molecular docking studies of novel cyclic pentapeptides based on phthaloyl chloride with expected anticancer activity FH Mohamed, A Shalaby, A Abdelazem, M Mounier, E Nossier, ... Egyptian Journal of Chemistry 63 (5), 1723-1736, 2020 | 27 | 2020 |
Thymoquinone alleviates mitochondrial viability and apoptosis in diclofenac-induced acute kidney injury (AKI) via regulating Mfn2 and miR-34a mRNA expressions KS Hashem, AZ Abdelazem, MA Mohammed, AM Nagi, BE Aboulhoda, ... Environmental Science and Pollution Research 28, 10100-10113, 2021 | 26 | 2021 |
Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors BS Park, MM Al-Sanea, AZ Abdelazem, HM Park, EJ Roh, HM Park, ... Bioorganic & Medicinal Chemistry 22 (15), 3871-3878, 2014 | 24 | 2014 |
Synthesis and biological evaluation of new pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors AZ Abdelazem, MM Al-Sanea, BS Park, HM Park, KH Yoo, T Sim, JB Park, ... European Journal of Medicinal Chemistry 90, 195-208, 2015 | 20 | 2015 |
Development of carbapenem-based fluorogenic probes for the clinical screening of carbapenemase-producing bacteria J Kim, Y Kim, AZ Abdelazem, HJ Kim, H Choo, HS Kim, JO Kim, YJ Park, ... Bioorganic Chemistry 94, 103405, 2020 | 18 | 2020 |
ROS1 kinase inhibitors for molecular-targeted therapies MM Al-Sanea, AZ Abdelazem, BS Park, KH Yoo, T Sim, YJ Kwon, SH Lee Current medicinal chemistry 23 (2), 142-160, 2016 | 17 | 2016 |
Synthesis and in Vitro Screening of Phenylbipyridinylpyrazole Derivatives as Potential Antiproliferative Agents MM Al-Sanea, A Elkamhawy, A Zakaria, BS Park, Y Kwon, SH Lee, ... Molecules 20 (1), 1031-1045, 2015 | 15 | 2015 |
Synthesis of new diarylamides with pyrimidinyl pyridine scaffold and evaluation of their anti-proliferative effect on cancer cell lines AZ Abdelazem, MM Al-Sanea, HM Park, SH Lee Bioorganic & Medicinal Chemistry Letters 26 (4), 1301-1304, 2016 | 12 | 2016 |
Optimization of bipyridinyl pyrazole scaffolds via design, synthesis and screening of a new series of ros1 kinase‐modulating compounds MM Al‐Sanea, BS Park, AZ Abdelazem, KB Selim, KH Yoo, T Sim, JS Tae, ... Bulletin of the Korean Chemical Society 36 (1), 305-311, 2015 | 10 | 2015 |
Enantioselective sulfoxidation using Streptomyces glaucescens GLA. 0 S Salama, T Dishisha, MH Habib, AZ Abdelazem, W Bakeer, ... RSC advances 10 (54), 32335-32344, 2020 | 8 | 2020 |
Synthesis and in vitro antiproliferative activity of new 1-phenyl-3-(4-(pyridin-3-yl) phenyl) urea scaffold-based compounds MM Al-Sanea, MS Ali Khan, AZ Abdelazem, SH Lee, PL Mok, M Gamal, ... Molecules 23 (2), 297, 2018 | 8 | 2018 |
Thymoquinone attenuates 6-mercaptopurine induced testicular toxicity in albino rats: possible mechanisms are involved NW Abdelbaky, AZ Abdelazem, KS Hashem Adv. Anim. Vet. Sci 8 (6), 653-660, 2020 | 7 | 2020 |
General Co-catalytic Hydrothiolation of gem-Difluoroalkenes JP Sorrentino, RM Herrick, MK Abd El-Gaber, AZ Abdelazem, A Kumar, ... The Journal of organic chemistry 87 (24), 16676-16690, 2022 | 5 | 2022 |
Synthesis and biological evaluation of new pyrimidine-4-yl-ethanol derivatives as ROS1 kinase inhibitors AZ Abdelazem, SH Lee Journal of Enzyme Inhibition and Medicinal Chemistry 30 (2), 290-298, 2015 | 2 | 2015 |
Design, synthesis, biological evaluation, in silico ADME prediction and molecular docking of pyrazole-benzamides as multitargeting protien kinase inhibitors NA Khaled, NS Ahmed, AZ Abdelazem, NA Mohamed, AF El-Sayed, ... Journal of Molecular Structure 1288, 135753, 2023 | 1 | 2023 |
Clay Nanoparticles Ameliorate the Reproductive Toxicity Induced By Silver Nanoparticles in Adult Male Rats YE Ahmed, A Ragab, A Abdelazem, W Moselhy Egyptian Journal of Chemistry, 2024 | | 2024 |