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Deniz Kirik
Deniz Kirik
Professor of Neuroscience
Verified email at med.lu.se
Title
Cited by
Cited by
Year
Neuronal replacement from endogenous precursors in the adult brain after stroke
A Arvidsson, T Collin, D Kirik, Z Kokaia, O Lindvall
Nature medicine 8 (9), 963-970, 2002
36152002
Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system
D Kirik, C Rosenblad, C Burger, C Lundberg, TE Johansen, N Muzyczka, ...
Journal of Neuroscience 22 (7), 2780-2791, 2002
8922002
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
D Kirik, C Rosenblad, A Björklund
Experimental neurology 152 (2), 259-277, 1998
8041998
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
M Lundblad, M Andersson, C Winkler, D Kirik, N Wierup, MA Cenci
European Journal of Neuroscience 15 (1), 120-132, 2002
7752002
Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats
M Carta, T Carlsson, D Kirik, A Björklund
Brain 130 (7), 1819-1833, 2007
7122007
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned …
D Kirik, C Rosenblad, A Björklund, RJ Mandel
Journal of Neuroscience 20 (12), 4686-4700, 2000
4902000
Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: a new primate model of Parkinson's disease
D Kirik, LE Annett, C Burger, N Muzyczka, RJ Mandel, A Björklund
Proceedings of the National Academy of Sciences 100 (5), 2884-2889, 2003
4872003
L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function
C Winkler, D Kirik, A Björklund, MA Cenci
Neurobiology of disease 10 (2), 165-186, 2002
4772002
Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat …
A Björklund, D Kirik, C Rosenblad, B Georgievska, C Lundberg, ...
Brain research 886 (1-2), 82-98, 2000
4302000
A general chemical method to regulate protein stability in the mammalian central nervous system
M Iwamoto, T Björklund, C Lundberg, D Kirik, TJ Wandless
Chemistry & biology 17 (9), 981-988, 2010
4162010
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
BA Horger, MC Nishimura, MP Armanini, LC Wang, KT Poulsen, ...
Journal of Neuroscience 18 (13), 4929-4937, 1998
4101998
Localized striatal delivery of GDNF as a treatment for Parkinson disease
D Kirik, B Georgievska, A Björklund
Nature neuroscience 7 (2), 105-110, 2004
3422004
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
A Björklund, C Rosenblad, C Winkler, D Kirik
Neurobiology of disease 4 (3-4), 186-200, 1997
3221997
Cell transplantation in Parkinson's disease: how can we make it work?
C Winkler, D Kirik, A Björklund
Trends in neurosciences 28 (2), 86-92, 2005
3162005
Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease
H Hall, S Reyes, N Landeck, C Bye, G Leanza, K Double, L Thompson, ...
Brain 137 (9), 2493-2508, 2014
3012014
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of l-DOPA-induced dyskinesia
A Munoz, Q Li, F Gardoni, E Marcello, C Qin, T Carlsson, D Kirik, ...
Brain 131 (12), 3380-3394, 2008
2842008
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the …
C Rosenblad, D Kirik, B Devaux, B Moffat, HS Phillips, A Björklund
European Journal of Neuroscience 11 (5), 1554-1566, 1999
2841999
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and …
L Thompson, P Barraud, E Andersson, D Kirik, A Björklund
Journal of Neuroscience 25 (27), 6467-6477, 2005
2832005
α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease
I Lastres-Becker, A Ulusoy, NG Innamorato, G Sahin, A Rábano, D Kirik, ...
Human molecular genetics 21 (14), 3173-3192, 2012
2752012
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral …
A Eslamboli, B Georgievska, RM Ridley, HF Baker, N Muzyczka, C Burger, ...
Journal of Neuroscience 25 (4), 769-777, 2005
2712005
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Articles 1–20