NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system GS Gunaratne, Y Yang, F Li, TF Walseth, JS Marchant Cell Calcium 75, 30-41, 2018 | 121 | 2018 |
The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel SK Park, GS Gunaratne, EG Chulkov, F Moehring, P McCusker, PI Dosa, ... Journal of Biological Chemistry 294 (49), 18873-18880, 2019 | 89 | 2019 |
Essential requirement for JPT2 in NAADP-evoked Ca2+ signaling GS Gunaratne, E Brailoiu, S He, EM Unterwald, S Patel, JT Slama, ... Science signaling 14 (675), eabd5605, 2021 | 86 | 2021 |
The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand JD Chan, PM Cupit, GS Gunaratne, JD McCorvy, Y Yang, K Stoltz, ... Nature communications 8 (1), 1910, 2017 | 64 | 2017 |
A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca2+ signaling in human cells GS Gunaratne, ME Johns, HM Hintz, TF Walseth, JS Marchant Cell Calcium 75, 42-52, 2018 | 29 | 2018 |
Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography OC Ubah, EW Lake, GS Gunaratne, JP Gallant, M Fernie, AJ Robertson, ... Nature communications 12 (1), 7325, 2021 | 26 | 2021 |
Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers GS Gunaratne, NA Yahya, PI Dosa, JS Marchant PLoS Neglected Tropical Diseases 12 (4), e0006420, 2018 | 20 | 2018 |
NAADP-binding proteins find their identity JS Marchant, GS Gunaratne, X Cai, JT Slama, S Patel Trends in biochemical sciences 47 (3), 235-249, 2022 | 19 | 2022 |
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells M Arhatte, GS Gunaratne, C El Boustany, IY Kuo, C Moro, F Duprat, ... Nature communications 10 (1), 2024, 2019 | 18 | 2019 |
5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors GS Gunaratne, P Su, JS Marchant, JT Slama, TF Walseth Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (7), 1180-1188, 2019 | 16 | 2019 |
Activation of endo-lysosomal two-pore channels by NAADP and PI (3, 5) P2. Five things to know. S Patel, Y Yuan, GS Gunaratne, T Rahman, JS Marchant Cell Calcium 103, 102543, 2022 | 12 | 2022 |
The synthesis and characterization of a clickable-photoactive NAADP analog active in human cells TY Asfaha, GS Gunaratne, ME Johns, JS Marchant, TF Walseth, JT Slama Cell Calcium 83, 102060, 2019 | 11 | 2019 |
Electrophysiology of endolysosomal two-pore channels: A current account S Patel, Y Yuan, CC Chen, D Jaślan, G Gunaratne, C Grimm, T Rahman, ... Cells 11 (15), 2368, 2022 | 10 | 2022 |
Convergent activation of Ca2+ permeability in two-pore channel 2 through distinct molecular routes R Saito, Q Mu, Y Yuan, M Rubio-Alarcón, M Eznarriaga, P Zhao, ... Science signaling 16 (799), eadg0661, 2023 | 8 | 2023 |
Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12 GS Gunaratne, E Brailoiu, S Kumar, Y Yuan, JT Slama, TF Walseth, ... Science signaling 16 (799), eadg0485, 2023 | 8 | 2023 |
The ins and outs of virus trafficking through acidic Ca2+ stores GS Gunaratne, JS Marchant Cell Calcium 102, 102528, 2022 | 7 | 2022 |
Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake VS Subramanian, T Teafatiller, J Vidal, GS Gunaratne, CJ Rodriguez-Ortiz, ... International journal of biological macromolecules 192, 1178-1184, 2021 | 6 | 2021 |
Chemo-enzymatic synthesis of adenine substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs P Su, JD Bretz, GS Gunaratne, JS Marchant, TF Walseth, JT Slama Bioorganic & medicinal chemistry 30, 115901, 2021 | 5 | 2021 |
Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum GS Gunaratne, S Kumar, Y Lin-Moshier, JT Slama, E Brailoiu, S Patel, ... Journal of Biological Chemistry 299 (12), 2023 | 3 | 2023 |
NAADP receptors: A one-two S Patel, GS Gunaratne, JS Marchant, PC Biggin, T Rahman Cell calcium 100, 102478, 2021 | 3 | 2021 |