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Barun Mahata
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Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis
PK Parida, B Mahata, A Santra, S Chakraborty, Z Ghosh, S Raha, ...
Cell Death & Disease 9 (5), 448, 2018
482018
Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase
J Li, B Mahata, M Escobar, J Goell, K Wang, P Khemka, IB Hilton
Nature Communications 12 (1), 896, 2021
462021
Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway
M Kundu, B Mahata, A Banerjee, S Chakraborty, S Debnath, SS Ray, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1472-1489, 2016
352016
GBM derived gangliosides induce T cell apoptosis through activation of the caspase cascade involving both the extrinsic and the intrinsic pathway
B Mahata, S Biswas, P Rayman, A Chahlavi, J Ko, A Bhattacharjee, YT Li, ...
PloS one 10 (7), e0134425, 2015
332015
TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells
B Mahata, A Banerjee, M Kundu, U Bandyopadhyay, K Biswas
Scientific reports 5 (1), 9048, 2015
282015
Elevated histone H3 acetylation and loss of the Sp1–HDAC1 complex de-repress the GM2-synthase gene in renal cell carcinoma
A Banerjee, B Mahata, A Dhir, TK Mandal, K Biswas
Journal of Biological Chemistry 294 (3), 1005-1018, 2019
262019
Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer–promoter interactions
K Wang, M Escobar, J Li, B Mahata, J Goell, S Shah, M Cluck, IB Hilton
Nucleic Acids Research 50 (14), 7842-7855, 2022
152022
Compact engineered human transactivation modules enable potent and versatile synthetic transcriptional control
B Mahata, J Li, A Cabrera, DA Brenner, RS Guerra-Resendez, J Goell, ...
BioRxiv, 2022-03, 2022
9*2022
Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis
S Debnath, A Sarkar, DD Mukherjee, S Ray, B Mahata, T Mahata, ...
Translational Oncology 21, 101433, 2022
72022
Generation of stable knockout mammalian cells by TALEN-mediated locus-specific gene editing
B Mahata, K Biswas
In Vitro Mutagenesis: Methods and Protocols, 107-120, 2017
42017
Persistent tailoring of MSC activation through genetic priming
MA Beauregard, GC Bedford, DA Brenner, LD Sanchez Solis, ...
bioRxiv, 2024.02. 01.578489, 2024
2024
Combining compact human protein domains with CRISPR systems for robust gene activation
B Mahata, IB Hilton
NATURE METHODS 20 (11), 1635-1636, 2023
2023
Engineered multipartite transcriptional effectors sourced from human protein domains
IH Barun MAHATA, Jacob GOELL
2023
Ganglioside GM2 mediated tumor growth, progression, and metastasis involves YAP-dependent transcriptional program
B Mahata, A Sarkar, E Khamrui, S Chakraborty, Z Ghosh, K Biswas
Cancer Research 78 (13_Supplement), 1110-1110, 2018
2018
Study the role and elucidate the mechanism of tumor derived gangliosides in tumor growth progression and metastasis in syngenic mouse tumor model
B Mahata
Kolkata, 2017
2017
GM2 mediates tumor cell migration and induces EMT through involvement of the integrin signaling machinery and targeting YAP, a major component of the HIPPO signaling pathway
M Kundu, B Mahata, A Banerjee, S Debnath, K Biswas
Cancer Research 76 (14_Supplement), 5146-5146, 2016
2016
Research briefing
B Mahata, IB Hilton
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Articles 1–17