A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits DM Feliciano, TV Lin, NW Hartman, CM Bartley, C Kubera, L Hsieh, ... International Journal of Developmental Neuroscience 31 (7), 667-678, 2013 | 92 | 2013 |
An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior Y Jung, LS Hsieh, AM Lee, Z Zhou, D Coman, CJ Heath, F Hyder, ... Nature neuroscience 19 (7), 905-914, 2016 | 90 | 2016 |
Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement LS Hsieh, JH Wen, K Claycomb, Y Huang, FA Harrsch, JR Naegele, ... Nature communications 7 (1), 11753, 2016 | 89 | 2016 |
Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration TV Lin, L Hsieh, T Kimura, TJ Malone, A Bordey Proceedings of the National Academy of Sciences 113 (40), 11330-11335, 2016 | 60 | 2016 |
Outbred CD1 mice are as suitable as inbred C57BL/6J mice in performing social tasks LS Hsieh, JH Wen, L Miyares, PJ Lombroso, A Bordey Neuroscience letters 637, 142-147, 2017 | 59 | 2017 |
MEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR L Zhang, CM Bartley, X Gong, LS Hsieh, TV Lin, DM Feliciano, A Bordey Neuron 84 (1), 78-91, 2014 | 48 | 2014 |
Rheb activation in subventricular zone progenitors leads to heterotopia, ectopic neuronal differentiation, and rapamycin-sensitive olfactory micronodules and dendrite … CA Lafourcade, TV Lin, DM Feliciano, L Zhang, LS Hsieh, A Bordey Journal of Neuroscience 33 (6), 2419-2431, 2013 | 48 | 2013 |
Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo X Gong, L Zhang, T Huang, TV Lin, L Miyares, J Wen, L Hsieh, A Bordey Human molecular genetics 24 (20), 5746-5758, 2015 | 42 | 2015 |
Dendrodendritic synapses in the mouse olfactory bulb external plexiform layer DL Bartel, L Rela, L Hsieh, CA Greer Journal of Comparative Neurology 523 (8), 1145-1161, 2015 | 33 | 2015 |
Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformations L Zhang, T Huang, S Teaw, LH Nguyen, LS Hsieh, X Gong, LH Burns, ... Science Translational Medicine 12 (531), eaay0289, 2020 | 27 | 2020 |
Ectopic HCN4 expression drives mTOR-dependent epilepsy in mice LS Hsieh, JH Wen, LH Nguyen, L Zhang, SA Getz, J Torres-Reveron, ... Science translational medicine 12 (570), eabc1492, 2020 | 25 | 2020 |
Conditional knockout of tumor overexpressed gene in mouse neurons affects RNA granule assembly, granule translation, LTP and short term habituation E Barbarese, MF Ifrim, L Hsieh, C Guo, V Tatavarty, MJ Maggipinto, ... PloS one 8 (8), e69989, 2013 | 19 | 2013 |
Valnoctamide inhibits cytomegalovirus infection in developing brain and attenuates neurobehavioral dysfunctions and brain abnormalities S Ornaghi, LS Hsieh, A Bordey, P Vergani, MJ Paidas, AN van den Pol Journal of Neuroscience 37 (29), 6877-6893, 2017 | 17 | 2017 |
Cannabinoid modulation of backpropagating action potential-induced calcium transients in layer 2/3 pyramidal neurons LS Hsieh, ES Levine Cerebral cortex 23 (7), 1731-1741, 2013 | 10 | 2013 |
Rab27a-dependent paracrine communication controls dendritic spine formation and sensory responses in the barrel cortex L Zhang, X Zhang, LS Hsieh, TV Lin, A Bordey Cells 10 (3), 622, 2021 | 6 | 2021 |
Targeting cap-dependent translation to reduce seizures in mtor disorders A Bordey, L Nguyen, L Hsieh, T Lin US Patent App. 17/766,455, 2024 | | 2024 |
Excitation-Inhibition Neurotransmission Imbalance in Cortical Organoids Derived From Children With Autism Spectrum Disorder E Yuen, A Amiri, L Hsieh, A Bordey, F Vaccarino NEUROPSYCHOPHARMACOLOGY 44 (SUPPL 1), 235-235, 2019 | | 2019 |
Ectopic HCN4 expression drives mTOR-dependent epilepsy LS Hsieh, JH Wen, LH Nguyen, L Zhang, J Torres-Reveron, DD Spencer, ... bioRxiv, 853820, 2019 | | 2019 |
Valnoctamide inhibits cytomegalovirus infection in the developing brain and attenuates virally induced brain defects and neurological dysfunctions S Ornaghi, L Hsieh, A Bordey, P Vergani, M Paidas, A van den Pol | | 2017 |
Intracerebral Schwannoma in Parietooccipital Lobe L Zhang, X Gong, Z Sun, T Huang, L Hsieh, J Fang, M Zhang Neurosurgery Quarterly 25 (3), 331-333, 2015 | | 2015 |