Julio Saez Rodriguez
TitleCited byYear
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570, 2012
15922012
Prospective derivation of a living organoid biobank of colorectal cancer patients
M van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ...
Cell 161 (4), 933-945, 2015
6682015
Structural and functional analysis of cellular networks with CellNetAnalyzer
S Klamt, J Saez-Rodriguez, ED Gilles
BMC systems biology 1 (1), 2, 2007
5022007
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
4772016
Critical assessment of automated flow cytometry data analysis techniques
N Aghaeepour, G Finak, H Hoos, TR Mosmann, R Brinkman, R Gottardo, ...
Nature methods 10 (3), 228, 2013
4102013
A methodology for the structural and functional analysis of signaling and regulatory networks
S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles
BMC bioinformatics 7 (1), 56, 2006
3942006
Towards a rigorous assessment of systems biology models: the DREAM3 challenges
RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ...
PloS one 5 (2), e9202, 2010
3812010
A community effort to assess and improve drug sensitivity prediction algorithms
JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ...
Nature biotechnology 32 (12), 1202, 2014
3392014
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ...
Molecular systems biology 5 (1), 2009
3132009
A logical model provides insights into T cell receptor signaling
J Saez-Rodriguez, L Simeoni, JA Lindquist, R Hemenway, U Bommhardt, ...
PLoS computational biology 3 (8), e163, 2007
3102007
Logic-based models for the analysis of cell signaling networks
MK Morris, J Saez-Rodriguez, PK Sorger, DA Lauffenburger
Biochemistry 49 (15), 3216-3224, 2010
2792010
Evaluation of methods for modeling transcription factor sequence specificity
MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ...
Nature biotechnology 31 (2), 126, 2013
2592013
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ...
PLoS one 8 (4), e61318, 2013
2022013
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
DM Wittmann, J Krumsiek, J Saez-Rodriguez, DA Lauffenburger, S Klamt, ...
BMC systems biology 3 (1), 98, 2009
1942009
The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data
R Samaga, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, S Klamt
PLoS computational biology 5 (8), e1000438, 2009
1932009
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH da Costa, ...
Nature 537 (7621), 544, 2016
1872016
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
1772016
Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling
BB Aldridge, J Saez-Rodriguez, JL Muhlich, PK Sorger, DA Lauffenburger
PLoS computational biology 5 (4), e1000340, 2009
1582009
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms
C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ...
BMC systems biology 6 (1), 133, 2012
1452012
Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli
MK Morris, J Saez-Rodriguez, DC Clarke, PK Sorger, DA Lauffenburger
PLoS computational biology 7 (3), e1001099, 2011
1372011
The system can't perform the operation now. Try again later.
Articles 1–20