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Richard J Youle
Richard J Youle
National Institutes of Health
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13181*2021
The BCL-2 protein family: opposing activities that mediate cell death
RJ Youle, A Strasser
Nature reviews Molecular cell biology 9 (1), 47-59, 2008
56332008
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
D Narendra, A Tanaka, DF Suen, RJ Youle
The Journal of cell biology 183 (5), 795-803, 2008
41722008
Mitochondrial fission, fusion, and stress
RJ Youle, AM Van Der Bliek
Science 337 (6098), 1062-1065, 2012
34562012
Mechanisms of mitophagy
RJ Youle, DP Narendra
Nature reviews Molecular cell biology 12 (1), 9-14, 2011
34282011
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
DP Narendra, SM Jin, A Tanaka, DF Suen, CA Gautier, J Shen, ...
PLoS biology 8 (1), e1000298, 2010
29732010
Movement of Bax from the cytosol to mitochondria during apoptosis
KG Wolter, YT Hsu, CL Smith, A Nechushtan, XG Xi, RJ Youle
The Journal of cell biology 139 (5), 1281-1292, 1997
24121997
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ...
Nature 524 (7565), 309-314, 2015
23562015
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
HC Gerstein, HM Colhoun, GR Dagenais, R Diaz, M Lakshmanan, P Pais, ...
The Lancet 394 (10193), 121-130, 2019
22702019
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson’s disease
AM Pickrell, RJ Youle
Neuron 85 (2), 257-273, 2015
21622015
The role of mitochondria in apoptosis
C Wang, RJ Youle
Annual review of genetics 43, 95-118, 2009
20992009
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
S Frank, B Gaume, ES Bergmann-Leitner, WW Leitner, EG Robert, ...
Developmental cell 1 (4), 515-525, 2001
20512001
Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics
JC Martinou, RJ Youle
Developmental cell 21 (1), 92-101, 2011
16602011
Mitophagy and quality control mechanisms in mitochondrial maintenance
S Pickles, P Vigié, RJ Youle
Current Biology 28 (4), R170-R185, 2018
15832018
Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis
YT Hsu, KG Wolter, RJ Youle
Proceedings of the National Academy of Sciences 94 (8), 3668-3672, 1997
15671997
Mitochondrial dynamics and apoptosis
DF Suen, KL Norris, RJ Youle
Genes & development 22 (12), 1577-1590, 2008
15172008
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
A Tanaka, MM Cleland, S Xu, DP Narendra, DF Suen, M Karbowski, ...
Journal of Cell Biology 191 (7), 1367-1380, 2010
14432010
Structure of Bax: coregulation of dimer formation and intracellular localization
M Suzuki, RJ Youle, N Tjandra
Cell 103 (4), 645-654, 2000
14142000
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle
Journal of Cell Biology 191 (5), 933-942, 2010
13712010
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
Y Lee, SY Jeong, M Karbowski, CL Smith, RJ Youle
Molecular biology of the cell 15 (11), 5001-5011, 2004
12982004
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