Exploring the sequence determinants of amyloid structure using position-specific scoring matrices S Maurer-Stroh, M Debulpaep, N Kuemmerer, ML De La Paz, IC Martins, ... Nature methods 7 (3), 237-242, 2010 | 694 | 2010 |
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations YC Lin, M Boone, L Meuris, I Lemmens, N Van Roy, A Soete, J Reumers, ... Nature communications 5 (1), 4767, 2014 | 649 | 2014 |
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations YC Lin, M Boone, L Meuris, I Lemmens, N Van Roy, A Soete, J Reumers, ... Nature communications 5 (1), 4767, 2014 | 646 | 2014 |
A scalable SCENIC workflow for single-cell gene regulatory network analysis B Van de Sande, C Flerin, K Davie, M De Waegeneer, G Hulselmans, ... Nature protocols 15 (7), 2247-2276, 2020 | 613 | 2020 |
Gain of function of mutant p53 by coaggregation with multiple tumor suppressors J Xu, J Reumers, JR Couceiro, F De Smet, R Gallardo, S Rudyak, ... Nature chemical biology 7 (5), 285-295, 2011 | 565 | 2011 |
SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants G De Baets, J Van Durme, J Reumers, S Maurer-Stroh, P Vanhee, ... Nucleic acids research 40 (D1), D935-D939, 2012 | 281 | 2012 |
PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes L Conde, JM Vaquerizas, H Dopazo, L Arbiza, J Reumers, F Rousseau, ... Nucleic acids research 34 (suppl_2), W621-W625, 2006 | 260 | 2006 |
Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing J Reumers, P De Rijk, H Zhao, A Liekens, D Smeets, J Cleary, P Van Loo, ... Nature biotechnology 30 (1), 61-68, 2012 | 252 | 2012 |
VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials D Lambrechts, B Claes, P Delmar, J Reumers, M Mazzone, BT Yesilyurt, ... The lancet oncology 13 (7), 724-733, 2012 | 212 | 2012 |
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs J Reumers, J Schymkowitz, J Ferkinghoff-Borg, F Stricher, L Serrano, ... Nucleic acids research 33 (suppl_1), D527-D532, 2005 | 184 | 2005 |
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease V Bogaerts, K Nuytemans, J Reumers, P Pals, S Engelborghs, B Pickut, ... Human mutation 29 (6), 832-840, 2008 | 142 | 2008 |
Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer … RL Milne, MM Gaudet, AB Spurdle, PA Fasching, FJ Couch, J Benítez, ... Breast cancer research 12, 1-11, 2010 | 118 | 2010 |
SNPeffect v2. 0: a new step in investigating the molecular phenotypic effects of human non-synonymous SNPs J Reumers, S Maurer-Stroh, J Schymkowitz, F Rousseau Bioinformatics 22 (17), 2183-2185, 2006 | 109 | 2006 |
Halvade: scalable sequence analysis with MapReduce D Decap, J Reumers, C Herzeel, P Costanza, J Fostier Bioinformatics 31 (15), 2482-2488, 2015 | 105 | 2015 |
PepX: a structural database of non-redundant protein–peptide complexes P Vanhee, J Reumers, F Stricher, L Baeten, L Serrano, J Schymkowitz, ... Nucleic acids research 38 (suppl_1), D545-D551, 2010 | 105 | 2010 |
Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks H Zhao, B Thienpont, BT Yesilyurt, M Moisse, J Reumers, L Coenegrachts, ... Elife 3, e02725, 2014 | 104 | 2014 |
Protein sequences encode safeguards against aggregation J Reumers, S Maurer‐Stroh, J Schymkowitz, F Rousseau Human mutation 30 (3), 431-437, 2009 | 99 | 2009 |
Efficiency of whole genome amplification of single circulating tumor cells enriched by CellSearch and sorted by FACS JF Swennenhuis, J Reumers, K Thys, J Aerssens, LWMM Terstappen Genome medicine 5, 1-11, 2013 | 93 | 2013 |
Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases J Reumers, L Conde, I Medina, S Maurer-Stroh, J Van Durme, J Dopazo, ... Nucleic acids research 36 (suppl_1), D825-D829, 2008 | 92 | 2008 |
VirVarSeq: a low-frequency virus variant detection pipeline for Illumina sequencing using adaptive base-calling accuracy filtering BMP Verbist, K Thys, J Reumers, Y Wetzels, K Van der Borght, W Talloen, ... Bioinformatics 31 (1), 94-101, 2015 | 70 | 2015 |