| Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks WG Lewis, LG Green, F Grynszpan, Z Radić, PR Carlier, P Taylor, ... Angewandte Chemie International Edition 41 (6), 1053-1057, 2002 | 1075 | 2002 |
| In situ click chemistry: enzyme inhibitors made to their own specifications R Manetsch, A Krasiński, Z Radić, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 126 (40), 12809-12818, 2004 | 607 | 2004 |
| Three distinct domains in the cholinesterase molecule confer selectivity for acetyl-and butyrylcholinesterase inhibitors Z Radic, NA Pickering, DC Vellom, S Camp, P Taylor Biochemistry 32 (45), 12074-12084, 1993 | 549 | 1993 |
| In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors A Krasiński, Z Radić, R Manetsch, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 127 (18), 6686-6692, 2005 | 468 | 2005 |
| Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site Y Bourne, P Taylor, Z Radić, P Marchot The EMBO journal, 2003 | 439 | 2003 |
| Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation Y Bourne, HC Kolb, Z Radić, KB Sharpless, P Taylor, P Marchot Proceedings of the National Academy of Sciences 101 (6), 1449-1454, 2004 | 391 | 2004 |
| Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives. Z Radić, E Reiner, P Taylor Molecular pharmacology 39 (1), 98-104, 1991 | 227 | 1991 |
| Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism Y Bourne, Z Radić, R Aráoz, TT Talley, E Benoit, D Servent, P Taylor, ... Proceedings of the National Academy of Sciences 107 (13), 6076-6081, 2010 | 201 | 2010 |
| Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore TT Talley, M Harel, RE Hibbs, Z Radić, M Tomizawa, JE Casida, P Taylor Proceedings of the National Academy of Sciences 105 (21), 7606-7611, 2008 | 189 | 2008 |
| Site of fasciculin interaction with acetylcholinesterase Z Radić, R Duran, DC Vellom, Y Li, C Cervenansky, P Taylor Journal of biological Chemistry 269 (15), 11233-11239, 1994 | 171 | 1994 |
| Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis L Wong, Z Radić, RJM Brüggemann, N Hosea, HA Berman, P Taylor Biochemistry 39 (19), 5750-5757, 2000 | 166 | 2000 |
| Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates Z Kovarik, Z Radić, HA Berman, V Simeon-Rudolf, E Reiner, P Taylor Biochemical Journal 373 (1), 33-40, 2003 | 150 | 2003 |
| New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases RK Sit, Z Radić, V Gerardi, L Zhang, E Garcia, M Katalinić, G Amitai, ... Journal of Biological Chemistry 286 (22), 19422-19430, 2011 | 146 | 2011 |
| Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates Z Kovarik, Z Radić, HA Berman, V Simeon-Rudolf, E Reiner, P Taylor Biochemistry 43 (11), 3222-3229, 2004 | 141 | 2004 |
| Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases Z Radić, RK Sit, Z Kovarik, S Berend, E Garcia, L Zhang, G Amitai, ... Journal of Biological Chemistry 287 (15), 11798-11809, 2012 | 130 | 2012 |
| Allosteric Control of Acetylcholinesterase Catalysis by Fasciculin (∗) Z Radić, DM Quinn, DC Vellom, S Camp, P Taylor Journal of Biological Chemistry 270 (35), 20391-20399, 1995 | 112 | 1995 |
| Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium C Luo, A Saxena, M Smith, G Garcia, Z Radić, P Taylor, BP Doctor Biochemistry 38 (31), 9937-9947, 1999 | 102 | 1999 |
| Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates NA Hosea, Z Radić, I Tsigelny, HA Berman, DM Quinn, P Taylor Biochemistry 35 (33), 10995-11004, 1996 | 96 | 1996 |
| Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes Z Radić, T Dale, Z Kovarik, S Berend, E Garcia, L Zhang, G Amitai, ... Biochemical Journal 450 (1), 231-242, 2013 | 94 | 2013 |
| Aromatic amino‐acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept®) to cholinesterases A Saxena, JM Fedorko, CR Vinayaka, R Medhekar, Z Radić, P Taylor, ... European journal of biochemistry 270 (22), 4447-4458, 2003 | 93 | 2003 |
