| Function and Antagonism of β3 integrins in the development of cancer therapy HM Sheldrake, LH Patterson Current cancer drug targets 9 (4), 519-540, 2009 | 103 | 2009 |
| Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists: miniperspective HM Sheldrake, LH Patterson Journal of medicinal chemistry 57 (15), 6301-6315, 2014 | 100 | 2014 |
| RGD-binding integrins in prostate cancer: expression patterns and therapeutic prospects against bone metastasis M Sutherland, A Gordon, SD Shnyder, LH Patterson, HM Sheldrake Cancers 4 (4), 1106-1145, 2012 | 71 | 2012 |
| The Changing Faces of Halogenated Marine Natural Products: Total Synthesis of the Reported Structures of Elatenyne and an Enyne from Laurencia majuscula HM Sheldrake, C Jamieson, JW Burton Angewandte Chemie 118 (43), 7357-7360, 2006 | 71 | 2006 |
| Chemical and biological explorations of the family of CC-1065 and the duocarmycin natural products N Ghosh, HM Sheldrake, M Searcey, K Pors Current topics in medicinal chemistry 9 (16), 1494-1524, 2009 | 62 | 2009 |
| Colon Cancer–Specific Cytochrome P450 2W1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins S Travica, K Pors, PM Loadman, SD Shnyder, I Johansson, MN Alandas, ... Clinical Cancer Research 19 (11), 2952-2961, 2013 | 61 | 2013 |
| Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder M Sutherland, JH Gill, PM Loadman, JP Laye, HM Sheldrake, ... Molecular cancer therapeutics 12 (1), 27-37, 2013 | 52 | 2013 |
| Synthesis of the originally proposed structures of elatenyne and an enyne from Laurencia majuscula HM Sheldrake, C Jamieson, SI Pascu, JW Burton Organic & biomolecular chemistry 7 (2), 238-252, 2009 | 50 | 2009 |
| Synthesis of SB-214857 using copper catalysed amination of arylbromides with L-aspartic acid JB Clement, JF Hayes, HM Sheldrake, PW Sheldrake, AS Wells Synlett 2001 (09), 1423-1427, 2001 | 46 | 2001 |
| Re-engineering of the duocarmycin structural architecture enables bioprecursor development targeting CYP1A1 and CYP2W1 for biological activity HM Sheldrake, S Travica, I Johansson, PM Loadman, M Sutherland, ... Journal of medicinal chemistry 56 (15), 6273-6277, 2013 | 41 | 2013 |
| Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity K Pors, PM Loadman, SD Shnyder, M Sutherland, HM Sheldrake, ... Chemical communications 47 (44), 12062-12064, 2011 | 41 | 2011 |
| Functionalized cyclobutenes via multicomponent thermal [2+ 2] cycloaddition reactions HM Sheldrake, TW Wallace, CP Wilson Organic Letters 7 (19), 4233-4236, 2005 | 36 | 2005 |
| RGD-binding integrins in head and neck cancers HT Ahmedah, LH Patterson, SD Shnyder, HM Sheldrake Cancers 9 (6), 56, 2017 | 33 | 2017 |
| Manganese (III) acetate mediated synthesis of oxygen heterocycles. Influence of copper (II) salts on product distribution DG Hulcoop, HM Sheldrake, JW Burton Organic & Biomolecular Chemistry 2 (7), 965-967, 2004 | 30 | 2004 |
| Reduction of propargylic sulfones to Z-allylic sulfones using zinc and ammonium chloride HM Sheldrake, TW Wallace Tetrahedron letters 48 (25), 4407-4411, 2007 | 27 | 2007 |
| Solid-phase synthesis of duocarmycin analogues and the effect of C-terminal substitution on biological activity MJ Stephenson, LA Howell, MA O’connell, KR Fox, C Adcock, J Kingston, ... The Journal of organic chemistry 80 (19), 9454-9467, 2015 | 17 | 2015 |
| Kinetic and thermodynamic control of axial chirality in biaryl-derived fused oxazolidine lactams exploiting a centre-axis relay of unit efficiency DJ Edwards, D House, HM Sheldrake, SJ Stone, TW Wallace Organic & Biomolecular Chemistry 5 (16), 2658-2669, 2007 | 17 | 2007 |
| Rapid stereoselective access to the tetracyclic core of puupehenone and related sponge metabolites using metal-free radical cyclisations of cyclohexenyl-substituted 3 … RG Pritchard, HM Sheldrake, IZ Taylor, TW Wallace Tetrahedron Letters 49 (26), 4156-4159, 2008 | 15 | 2008 |
| A short, efficient, and stereoselective synthesis of piperine and its analogues A Bauer, JH Nam, N Maulide Synlett 30 (04), 413-416, 2019 | 10 | 2019 |
| Intramolecular thermal stepwise [2+ 2] cycloadditions: investigation of a stereoselective synthesis of [n. 2.0]-bicyclolactones A Throup, LH Patterson, HM Sheldrake Organic & Biomolecular Chemistry 14 (40), 9554-9559, 2016 | 7 | 2016 |
