| Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio I Kuperstein, K Broersen, I Benilova, J Rozenski, W Jonckheere, ... The EMBO journal 29 (19), 3408-3420, 2010 | 665 | 2010 |
| The mechanism of γ‐secretase dysfunction in familial Alzheimer disease L Chávez‐Gutiérrez, L Bammens, I Benilova, A Vandersteen, M Benurwar, ... The EMBO journal 31 (10), 2261-2274, 2012 | 634 | 2012 |
| Alzheimer’s disease: treatment strategies and their limitations E Passeri, K Elkhoury, M Morsink, K Broersen, M Linder, A Tamayol, ... International journal of molecular sciences 23 (22), 13954, 2022 | 325 | 2022 |
| Structural basis for increased toxicity of pathological aβ42: aβ40 ratios in Alzheimer disease K Pauwels, TL Williams, KL Morris, W Jonckheere, A Vandersteen, ... Journal of biological chemistry 287 (8), 5650-5660, 2012 | 302 | 2012 |
| Molecular mechanisms and genetics of oxidative stress in Alzheimer’s disease F Cioffi, RHI Adam, K Broersen Journal of Alzheimer’s Disease 72 (4), 981-1017, 2019 | 227 | 2019 |
| The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation? K Broersen, F Rousseau, J Schymkowitz Alzheimer's research & therapy 2, 1-14, 2010 | 179 | 2010 |
| A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease K Broersen, W Jonckheere, J Rozenski, A Vandersteen, K Pauwels, ... Protein Engineering, Design & Selection 24 (9), 743-750, 2011 | 165 | 2011 |
| Amyloid precursor protein mutation E682K at the alternative β‐secretase cleavage β′‐site increases Aβ generation L Zhou, N Brouwers, I Benilova, A Vandersteen, M Mercken, K Van Laere, ... EMBO molecular medicine 3 (5), 291-302, 2011 | 136 | 2011 |
| Glycoforms of β‐lactoglobulin with improved thermostability and preserved structural packing K Broersen, AGJ Voragen, RJ Hamer, HHJ De Jongh Biotechnology and Bioengineering 86 (1), 78-87, 2004 | 113 | 2004 |
| Mechanism of arachidonic acid action on syntaxin–Munc18 E Connell, F Darios, K Broersen, N Gatsby, SY Peak‐Chew, C Rickman, ... EMBO reports 8 (4), 414-419, 2007 | 112 | 2007 |
| α-Synuclein adopts an α-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation K Broersen, D Van Den Brink, G Fraser, M Goedert, B Davletov Biochemistry 45 (51), 15610-15616, 2006 | 105 | 2006 |
| A comparative analysis of the aggregation behavior of amyloid-β peptide variants A Vandersteen, E Hubin, R Sarroukh, G De Baets, J Schymkowitz, ... FEBS letters 586 (23), 4088-4093, 2012 | 101 | 2012 |
| Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease E Hubin, NAJ Van Nuland, K Broersen, K Pauwels Cellular and Molecular Life Sciences 71, 3507-3521, 2014 | 98 | 2014 |
| Optimized Triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins M Teodorowicz, O Perdijk, I Verhoek, C Govers, HFJ Savelkoul, Y Tang, ... PloS one 12 (3), e0173778, 2017 | 89 | 2017 |
| Do sulfhydryl groups affect aggregation and gelation properties of ovalbumin? K Broersen, AMM Van Teeffelen, A Vries, AGJ Voragen, RJ Hamer, ... Journal of agricultural and food chemistry 54 (14), 5166-5174, 2006 | 82 | 2006 |
| Multiplexed blood–brain barrier organ-on-chip M Zakharova, MAP Do Carmo, MW Van Der Helm, MNS De Graaf, ... Lab on a Chip 20 (17), 3132-3143, 2020 | 72 | 2020 |
| Mechanistic insights in glycation-induced protein aggregation M Adrover, L Mariño, P Sanchis, K Pauwels, Y Kraan, P Lebrun, ... Biomacromolecules 15 (9), 3449-3462, 2014 | 65 | 2014 |
| Glucosylation of β‐lactoglobulin lowers the heat capacity change of unfolding; a unique way to affect protein thermodynamics AMM Van Teeffelen, K Broersen, HHJ de Jongh Protein Science 14 (8), 2187-2194, 2005 | 63 | 2005 |
| Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool A Vandersteen, MF Masman, G De Baets, W Jonckheere, K Van Der Werf, ... Journal of Biological Chemistry 287 (44), 36732-36743, 2012 | 59 | 2012 |
| A review of oxidative stress products and related genes in early Alzheimer’s disease F Cioffi, RHI Adam, R Bansal, K Broersen Journal of Alzheimer’s Disease 83 (3), 977-1001, 2021 | 57 | 2021 |
Bart De Stroopergewoon hoogleraar KU Leuven en onderzoeksdirecteur VIBVerified email at cme.vib-kuleuven.be
