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Parren
Parren
Leiden University Medical Center
Verified email at lumc.nl
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Year
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
DR Burton, J Pyati, R Koduri, SJ Sharp, GB Thornton, PWHI Parren, ...
Science 266 (5187), 1024-1027, 1994
14231994
The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless
F Rijsewijk, M Schuermann, E Wagenaar, P Parren, D Weigel, R Nusse
Cell 50 (4), 649-657, 1987
14121987
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
M De Weers, YT Tai, MS Van Der Veer, JM Bakker, T Vink, DCH Jacobs, ...
The Journal of Immunology 186 (3), 1840-1848, 2011
11752011
Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange
M Van Der Neut Kolfschoten, J Schuurman, M Losen, WK Bleeker, ...
Science 317 (5844), 1554-1557, 2007
11282007
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design
EO Saphire, PWHI Parren, R Pantophlet, MB Zwick, GM Morris, PM Rudd, ...
science 293 (5532), 1155-1159, 2001
11182001
Fc receptor but not complement binding is important in antibody protection against HIV
AJ Hessell, L Hangartner, M Hunter, CEG Havenith, FJ Beurskens, ...
Nature 449 (7158), 101-104, 2007
10462007
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
MB Zwick, AF Labrijn, M Wang, C Spenlehauer, EO Saphire, JM Binley, ...
Journal of virology 75 (22), 10892-10905, 2001
10322001
Bispecific antibodies: a mechanistic review of the pipeline
AF Labrijn, ML Janmaat, JM Reichert, PWHI Parren
Nature reviews Drug discovery 18 (8), 585-608, 2019
9652019
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
JL Teeling, RR French, MS Cragg, J van den Brakel, M Pluyter, H Huang, ...
Blood 104 (6), 1793-1800, 2004
8622004
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
PWHI Parren, PA Marx, AJ Hessell, A Luckay, J Harouse, C Cheng-Mayer, ...
Journal of virology 75 (17), 8340-8347, 2001
8302001
The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20
JL Teeling, WJM Mackus, LJJM Wiegman, JHN van den Brakel, SA Beers, ...
The Journal of Immunology 177 (1), 362-371, 2006
8272006
Complement is activated by IgG hexamers assembled at the cell surface
CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ...
Science 343 (6176), 1260-1263, 2014
7932014
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
AJ Hessell, P Poignard, M Hunter, L Hangartner, DM Tehrani, WK Bleeker, ...
Nature medicine 15 (8), 951-954, 2009
6822009
Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1
M Hezareh, AJ Hessell, RC Jensen, JGJ van de Winkel, PWHI Parren
Journal of virology 75 (24), 12161-12168, 2001
5272001
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
MB Overdijk, S Verploegen, M Bögels, M van Egmond, JJL van Bueren, ...
MAbs 7 (2), 311-320, 2015
5222015
On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2.
PW Parren, PA Warmerdam, LC Boeije, J Arts, NA Westerdaal, A Vlug, ...
The Journal of clinical investigation 90 (4), 1537-1546, 1992
4931992
The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity.
PWHI Parren, JP Moore, DR Burton, QJ Sattentau
4151999
In vitro characterization of five humanized OKT3 effector function variant antibodies
D Xu, ML Alegre, SS Varga, AL Rothermel, AM Collins, VL Pulito, ...
Cellular immunology 200 (1), 16-26, 2000
4082000
Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange
AF Labrijn, JI Meesters, BECG de Goeij, ETJ van den Bremer, J Neijssen, ...
Proceedings of the National Academy of Sciences 110 (13), 5145-5150, 2013
4042013
Targeting interleukin‐15 in patients with rheumatoid arthritis: a proof‐of‐concept study
B Baslund, N Tvede, B Danneskiold‐Samsoe, P Larsson, G Panayi, ...
Arthritis & Rheumatism 52 (9), 2686-2692, 2005
4002005
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