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Caitrin Crudden, Ph.D.
Caitrin Crudden, Ph.D.
Postdoctoral Researcher, Vrije University, Amsterdam
Verified email at vu.nl - Homepage
Title
Cited by
Cited by
Year
Targeting the IGF-1R: the tale of the tortoise and the hare
C Crudden, A Girnita, L Girnita
Frontiers in endocrinology 6, 139855, 2015
872015
The forces driving cancer extracellular vesicle secretion
MP Bebelman, E Janssen, DM Pegtel, C Crudden
Neoplasia 23 (1), 149-157, 2021
512021
The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?
C Crudden, M Ilic, N Suleymanova, C Worrall, A Girnita, L Girnita
Growth Hormone & IGF Research 25 (1), 2-12, 2015
422015
Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma
C Worrall, N Suleymanova, C Crudden, I Trocoli Drakensjö, E Candrea, ...
Oncogene 36 (23), 3274-3286, 2017
392017
Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes
N Suleymanova, C Crudden, T Shibano, C Worrall, I Oprea, A Tica, ...
Oncogene 36 (41), 5734-5744, 2017
382017
Below the surface: IGF-1R therapeutic targeting and its endocytic journey
C Crudden, D Song, S Cismas, E Trocmé, S Pasca, GA Calin, A Girnita, ...
Cells 8 (10), 1223, 2019
352019
Genome-wide screen for microRNAs reveals a role for miR-203 in melanoma metastasis
W Lohcharoenkal, KD Mahapatra, L Pasquali, C Crudden, L Kular, ...
Journal of Investigative Dermatology 138 (4), 882-892, 2018
352018
Blurring boundaries: receptor tyrosine kinases as functional G protein-coupled receptors
C Crudden, T Shibano, D Song, N Suleymanova, A Girnita, L Girnita
International review of cell and molecular biology 339, 1-40, 2018
332018
Chapter seven-when phosphorylation encounters ubiquitination: a balanced perspective on IGF-1R signaling
L Girnita, SI Takahashi, C Crudden, T Fukushima, C Worrall, H Furuta, ...
Progress in molecular biology and translational science 141, 277-311, 2016
242016
The convergence of extracellular vesicle and GPCR biology
MP Bebelman, C Crudden, DM Pegtel, MJ Smit
Trends in pharmacological sciences 41 (9), 627-640, 2020
222020
Enhanced response of melanoma cells to MEK inhibitors following unbiased IGF-1R down-regulation
N Suleymanova, C Crudden, C Worrall, A Dricu, A Girnita, L Girnita
Oncotarget 8 (47), 82256, 2017
202017
Inhibition of G Protein–Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth
C Crudden, T Shibano, D Song, MP Dragomir, S Cismas, J Serly, ...
Cancer research 81 (2), 501-514, 2021
172021
IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma
D Song, S Cismas, C Crudden, E Trocme, C Worrall, N Suleymanova, ...
Oncogene 41 (4), 600-611, 2022
102022
The tale of a tail: The secret behind IGF-1R’s oncogenic power
C Crudden, L Girnita
Science signaling 13 (633), eabb7887, 2020
72020
Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
MP Bebelman, IM Setiawan, ND Bergkamp, JR van Senten, C Crudden, ...
iScience 26 (8), 2023
12023
Differential Regulation of IGF-1 and Insulin Signaling by GRKs
L Girnita, A Girnita, C Crudden
G Protein-Coupled Receptor Kinases, 151-171, 2016
12016
Competing engagement of β-arrestin isoforms balances IGF1R/p53 signaling and controls melanoma cell chemotherapeutic responsiveness
S Cismas, S Pasca, C Crudden, I Trocoli Drakensjo, N Suleymanova, ...
Molecular cancer research 21 (12), 1288-1302, 2023
2023
Correction: IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma
D Song, S Cismas, C Crudden, E Trocme, C Worrall, N Suleymanova, ...
Oncogene 42 (11), 858-858, 2023
2023
Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition
MP Bebelman, C Crudden, B Snieder, E Thanou, CJM Langedijk, M Viola, ...
bioRxiv, 2023.02. 23.529257, 2023
2023
26653 Can β-arrestin isoforms control response of melanoma cells to chemotherapy?
A Girnita, C Crudden, N Suleymanova, L Girnita
Journal of the American Academy of Dermatology 85 (3), AB111, 2021
2021
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