Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig A Radhakrishnan, Y Ikeda, HJ Kwon, MS Brown, JL Goldstein Proceedings of the National Academy of Sciences 104 (16), 6511-6518, 2007 | 665 | 2007 |
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance A Radhakrishnan, JL Goldstein, JG McDonald, MS Brown Cell metabolism 8 (6), 512-521, 2008 | 605 | 2008 |
NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes RE Infante, ML Wang, A Radhakrishnan, HJ Kwon, MS Brown, ... Proceedings of the National Academy of Sciences 105 (40), 15287-15292, 2008 | 558 | 2008 |
Condensed complexes of cholesterol and phospholipids HM McConnell, A Radhakrishnan Biochimica et Biophysica Acta (BBA)-Biomembranes 1610 (2), 159-173, 2003 | 468 | 2003 |
Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain A Radhakrishnan, LP Sun, HJ Kwon, MS Brown, JL Goldstein Molecular cell 15 (2), 259-268, 2004 | 430 | 2004 |
Retrospective on cholesterol homeostasis: the central role of scap MS Brown, A Radhakrishnan, JL Goldstein Annual review of biochemistry 87, 783-807, 2018 | 393 | 2018 |
Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis A Das, MS Brown, DD Anderson, JL Goldstein, A Radhakrishnan elife 3, e02882, 2014 | 333 | 2014 |
Condensed complexes, rafts, and the chemical activity of cholesterol in membranes A Radhakrishnan, TG Anderson, HM McConnell Proceedings of the National Academy of Sciences 97 (23), 12422-12427, 2000 | 293 | 2000 |
Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop RE Infante, A Radhakrishnan, L Abi-Mosleh, LN Kinch, ML Wang, ... Journal of Biological Chemistry 283 (2), 1064-1075, 2008 | 277 | 2008 |
Condensed complexes of cholesterol and phospholipids A Radhakrishnan, HM McConnell Biophysical journal 77 (3), 1507-1517, 1999 | 269 | 1999 |
Purified NPC1 protein: I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein RE Infante, L Abi-Mosleh, A Radhakrishnan, JD Dale, MS Brown, ... Journal of Biological Chemistry 283 (2), 1052-1063, 2008 | 240 | 2008 |
Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells L Abi-Mosleh, RE Infante, A Radhakrishnan, JL Goldstein, MS Brown Proceedings of the National Academy of Sciences 106 (46), 19316-19321, 2009 | 228 | 2009 |
Chemical activity of cholesterol in membranes A Radhakrishnan, HM McConnell Biochemistry 39 (28), 8119-8124, 2000 | 199 | 2000 |
Condensed complexes in vesicles containing cholesterol and phospholipids A Radhakrishnan, H McConnell Proceedings of the National Academy of Sciences 102 (36), 12662-12666, 2005 | 192 | 2005 |
DNA sequencing using a four‐color confocal fluorescence capillary array scanner I Kheterpal, JR Scherer, SM Clark, A Radhakrishnan, J Ju, CL Ginther, ... Electrophoresis 17 (12), 1852-1859, 1996 | 177 | 1996 |
Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol RE Infante, A Radhakrishnan elife 6, e25466, 2017 | 149 | 2017 |
Cholesterol-phospholipid complexes in membranes A Radhakrishnan, HM McConnell Journal of the American Chemical Society 121 (2), 486-487, 1999 | 127 | 1999 |
Cholesterol stabilizes TAZ in hepatocytes to promote experimental non-alcoholic steatohepatitis X Wang, B Cai, X Yang, OO Sonubi, Z Zheng, R Ramakrishnan, H Shi, ... Cell metabolism 31 (5), 969-986. e7, 2020 | 126 | 2020 |
Molecular discrimination between two conformations of sphingomyelin in plasma membranes S Endapally, D Frias, M Grzemska, A Gay, DR Tomchick, ... Cell 176 (5), 1040-1053. e17, 2019 | 120 | 2019 |
Use of mutant 125I-perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells A Das, JL Goldstein, DD Anderson, MS Brown, A Radhakrishnan Proceedings of the National Academy of Sciences 110 (26), 10580-10585, 2013 | 120 | 2013 |