|Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway|
TW Kensler, N Wakabayashi, S Biswal
Annu. Rev. Pharmacol. Toxicol. 47, 89-116, 2007
|Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray|
RK Thimmulappa, KH Mai, S Srisuma, TW Kensler, M Yamamoto, ...
Cancer research 62 (18), 5196-5203, 2002
|Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice|
M Ramos-Gomez, MK Kwak, PM Dolan, K Itoh, M Yamamoto, P Talalay, ...
Proceedings of the National Academy of Sciences 98 (6), 3410-3415, 2001
|Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice|
T Rangasamy, CY Cho, RK Thimmulappa, L Zhen, SS Srisuma, ...
The Journal of clinical investigation 114 (9), 1248-1259, 2004
|Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers|
N Wakabayashi, AT Dinkova-Kostova, WD Holtzclaw, MI Kang, ...
Proceedings of the National Academy of Sciences 101 (7), 2040-2045, 2004
|Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo [a] pyrene-induced stomach tumors|
JW Fahey, X Haristoy, PM Dolan, TW Kensler, I Scholtus, KK Stephenson, ...
Proceedings of the National Academy of Sciences 99 (11), 7610-7615, 2002
|Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.|
Y Zhang, TW Kensler, CG Cho, GH Posner, P Talalay
Proceedings of the National Academy of Sciences 91 (8), 3147-3150, 1994
|Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis|
RK Thimmulappa, H Lee, T Rangasamy, SP Reddy, M Yamamoto, ...
The Journal of clinical investigation 116 (4), 984-995, 2016
|K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele …|
RH Hruban, AD Van Mansfeld, GJ Offerhaus, DH Van Weering, ...
The American journal of pathology 143 (2), 545, 1993
|Role of NRF2 in protection against hyperoxic lung injury in mice|
HY Cho, AE Jedlicka, SPM Reddy, TW Kensler, M Yamamoto, LY Zhang, ...
American journal of respiratory cell and molecular biology 26 (2), 175-182, 2002
|Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival|
MK Kwak, N Wakabayashi, K Itoh, H Motohashi, M Yamamoto, ...
Journal of Biological Chemistry 278 (10), 8135-8145, 2003
|Oxidative mechanisms in carcinogenesis|
KZ Guyton, TW Kensler
British medical bulletin 49 (3), 523-544, 1993
|Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis|
D Malhotra, E Portales-Casamar, A Singh, S Srivastava, D Arenillas, ...
Nucleic acids research 38 (17), 5718-5734, 2010
|Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice|
T Rangasamy, J Guo, WA Mitzner, J Roman, A Singh, AD Fryer, ...
The Journal of experimental medicine 202 (1), 47-59, 2005
|Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter|
MK Kwak, K Itoh, M Yamamoto, TW Kensler
Molecular and cellular biology 22 (9), 2883-2892, 2002
|Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology|
TW Kensler, BD Roebuck, GN Wogan, JD Groopman
Toxicological sciences 120 (suppl_1), S28-S48, 2011
|Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults|
WO Osburn, TW Kensler
Mutation Research/Reviews in Mutation Research 659 (1-2), 31-39, 2008
|The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice|
J Wakabayashi, Z Zhang, N Wakabayashi, Y Tamura, M Fukaya, ...
Journal of Cell Biology 186 (6), 805-816, 2009
|When NRF2 talks, who's listening?|
N Wakabayashi, SL Slocum, JJ Skoko, S Shin, TW Kensler
Antioxidants & redox signaling 13 (11), 1649-1663, 2010
|Nrf2: friend or foe for chemoprevention?|
TW Kensler, N Wakabayashi
Carcinogenesis 31 (1), 90-99, 2010