Dr. Charlotte Summers PhD MRCP FFICM
Dr. Charlotte Summers PhD MRCP FFICM
University Lecturer in Intensive Care Medicine, University of Cambridge, UK
Verified email at medschl.cam.ac.uk
TitleCited byYear
Neutrophil kinetics in health and disease
C Summers, SM Rankin, AM Condliffe, N Singh, AM Peters, ER Chilvers
Trends in immunology 31 (8), 318-324, 2010
7562010
Advances in neutrophil biology: clinical implications
AS Cowburn, AM Condliffe, N Farahi, C Summers, ER Chilvers
Chest 134 (3), 606-612, 2008
1882008
Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils
NN McGovern, AS Cowburn, L Porter, SR Walmsley, C Summers, ...
The Journal of Immunology 186 (1), 453-463, 2011
1062011
Pulmonary retention of primed neutrophils: a novel protective host response, which is impaired in the acute respiratory distress syndrome
C Summers, NR Singh, JF White, IM Mackenzie, A Johnston, C Solanki, ...
Thorax 69 (7), 623-629, 2014
792014
Investigation and management of an outbreak of multidrug-carbapenem-resistant Acinetobacter baumannii in Cambridge, UK
DA Enoch, C Summers, NM Brown, L Moore, MI Gillham, RM Burnstein, ...
Journal of Hospital Infection 70 (2), 109, 2008
672008
Use of 111-Indium–labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects
N Farahi, NR Singh, S Heard, C Loutsios, C Summers, CK Solanki, ...
Blood 120 (19), 4068-4071, 2012
462012
The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities
FR Millar, C Summers, MJ Griffiths, MR Toshner, AG Proudfoot
Thorax 71 (5), 462-473, 2016
432016
Recent changes in the management of community acquired pneumonia in adults
HJ Durrington, C Summers
BMJ 336 (7658), 1429-1433, 2008
432008
Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of α1-antitrypsin: implications for disease and drug design
B Gooptu, E Miranda, I Nobeli, M Mallya, A Purkiss, SCL Brown, ...
Journal of molecular biology 387 (4), 857-868, 2009
382009
Acute respiratory distress syndrome neutrophils have a distinct phenotype and are resistant to phosphoinositide 3-kinase inhibition
JK Juss, D House, A Amour, M Begg, J Herre, DML Storisteanu, ...
American journal of respiratory and critical care medicine 194 (8), 961-973, 2016
372016
Hypoxia upregulates neutrophil degranulation and potential for tissue injury
K Hoenderdos, KM Lodge, RA Hirst, C Chen, SGC Palazzo, ...
Thorax 71 (11), 1030-1038, 2016
352016
Acute lung injury results from failure of neutrophil de‐priming: a new hypothesis
NRP Singh, A Johnson, AM Peters, J Babar, ER Chilvers, C Summers
European journal of clinical investigation 42 (12), 1342-1349, 2012
322012
Definitions and pathophysiology of vasoplegic shock
S Lambden, BC Creagh-Brown, J Hunt, C Summers, LG Forni
Critical Care 22 (1), 174, 2018
242018
Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils.
AS Cowburn, C Summers, BJ Dunmore, N Farahi, RP Hayhoe, SJ Cook, ...
Am J Respir Cell Mol Biol 44, 879-887, 2011
22*2011
Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease
P Ruparelia, KR Szczepura, C Summers, CK Solanki, K Balan, ...
European journal of nuclear medicine and molecular imaging 38 (5), 911-919, 2011
222011
Mechanical deformation induces depolarization of neutrophils
AE Ekpenyong, N Toepfner, C Fiddler, M Herbig, W Li, G Cojoc, ...
Science advances 3 (6), e1602536, 2017
212017
Prediction of early unplanned intensive care unit readmission in a UK tertiary care hospital: a cross-sectional machine learning approach
T Desautels, R Das, J Calvert, M Trivedi, C Summers, DJ Wales, A Ercole
BMJ open 7 (9), e017199, 2017
202017
Mathematical modeling supports the presence of neutrophil depriming in vivo
C Summers, ER Chilvers, AM Peters
Physiological reports 2 (3), e00241, 2014
172014
Priming and de‐priming of neutrophil responses in vitro and in vivo
KL Vogt, C Summers, ER Chilvers, AM Condliffe
European journal of clinical investigation 48, e12967, 2018
142018
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury
A Proudfoot, A Bayliffe, CM O’Kane, T Wright, A Serone, PJ Bareille, ...
Thorax 73 (8), 723-730, 2018
142018
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