| Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets EZ Macosko, A Basu, R Satija, J Nemesh, K Shekhar, M Goldman, I Tirosh, ... Cell 161 (5), 1202-1214, 2015 | 7139 | 2015 |
| Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ... Science 344 (6190), 1396-1401, 2014 | 4556 | 2014 |
| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 4116 | 2016 |
| MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data G Finak, A McDavid, M Yajima, J Deng, V Gersuk, AK Shalek, CK Slichter, ... Genome biology 16, 1-13, 2015 | 2529 | 2015 |
| SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell 181 (5), 1016-1035. e19, 2020 | 2419 | 2020 |
| The human cell atlas A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ... elife 6, e27041, 2017 | 2130 | 2017 |
| Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells AK Shalek, R Satija, X Adiconis, RS Gertner, JT Gaublomme, ... Nature 498 (7453), 236-240, 2013 | 1367 | 2013 |
| A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1097 | 2018 |
| Single-cell RNA-seq reveals dynamic paracrine control of cellular variation AK Shalek, R Satija, J Shuga, JJ Trombetta, D Gennert, D Lu, P Chen, ... Nature 510 (7505), 363-369, 2014 | 1085 | 2014 |
| Intra-and inter-cellular rewiring of the human colon during ulcerative colitis CS Smillie, M Biton, J Ordovas-Montanes, KM Sullivan, G Burgin, ... Cell 178 (3), 714-730. e22, 2019 | 1001 | 2019 |
| Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells ML Suvā, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ... Cell 157 (3), 580-594, 2014 | 946 | 2014 |
| Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput TM Gierahn, MH Wadsworth, TK Hughes, BD Bryson, A Butler, R Satija, ... Nature methods 14 (4), 395-398, 2017 | 912 | 2017 |
| Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ... Cell 176 (6), 1265-1281. e24, 2019 | 819 | 2019 |
| Dynamic regulatory network controlling TH17 cell differentiation N Yosef, AK Shalek, JT Gaublomme, H Jin, Y Lee, A Awasthi, C Wu, ... Nature 496 (7446), 461-468, 2013 | 782 | 2013 |
| Systematic comparison of single-cell and single-nucleus RNA-sequencing methods J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ... Nature biotechnology 38 (6), 737-746, 2020 | 680 | 2020 |
| COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ... Nature 595 (7865), 107-113, 2021 | 657 | 2021 |
| Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits JT Robinson, M Jorgolli, AK Shalek, MH Yoon, RS Gertner, H Park Nature nanotechnology 7 (3), 180-184, 2012 | 643 | 2012 |
| Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells AK Shalek, JT Robinson, ES Karp, JS Lee, DR Ahn, MH Yoon, A Sutton, ... Proceedings of the National Academy of Sciences 107 (5), 1870-1875, 2010 | 633 | 2010 |
| Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ... Nature biotechnology 32 (5), 479-484, 2014 | 614 | 2014 |
| Single-cell genomics unveils critical regulators of Th17 cell pathogenicity JT Gaublomme, N Yosef, Y Lee, RS Gertner, LV Yang, C Wu, PP Pandolfi, ... Cell 163 (6), 1400-1412, 2015 | 605 | 2015 |
