The histone H3. 3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression KM Chan, D Fang, H Gan, R Hashizume, C Yu, M Schroeder, N Gupta, ... Genes & development 27 (9), 985-990, 2013 | 730 | 2013 |
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma R Hashizume, N Andor, Y Ihara, R Lerner, H Gan, X Chen, D Fang, ... Nature medicine 20 (12), 1394-1396, 2014 | 499 | 2014 |
Overview of Histone Modification Y Zhang, Z Sun, J Jia, T Du, N Zhang, Y Tang, Y Fang, D Fang Histone Mutations and Cancer, 1-16, 2021 | 446 | 2021 |
A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma X Chen, M Zhang, H Gan, H Wang, JH Lee, D Fang, GJ Kitange, L He, ... Nature communications 9 (1), 2949, 2018 | 308 | 2018 |
The histone H3. 3K36M mutation reprograms the epigenome of chondroblastomas D Fang, H Gan, JH Lee, J Han, Z Wang, SM Riester, L Jin, J Chen, ... Science 352 (6291), 1344-1348, 2016 | 262 | 2016 |
Identification of genes directly involved in shell formation and their functions in pearl oyster, Pinctada fucata D Fang, G Xu, Y Hu, C Pan, L Xie, R Zhang PLoS One 6 (7), e21860, 2011 | 139 | 2011 |
H3. 3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers D Fang, H Gan, L Cheng, JH Lee, H Zhou, JN Sarkaria, DJ Daniels, ... Elife 7, e36696, 2018 | 100 | 2018 |
H3K36me3, message from chromatin to DNA damage repair Z Sun, Y Zhang, J Jia, Y Fang, Y Tang, H Wu, D Fang Cell & bioscience 10, 1-9, 2020 | 99 | 2020 |
YAP drives fate conversion and chemoresistance of small cell lung cancer Q Wu, J Guo, Y Liu, Q Zheng, X Li, C Wu, D Fang, X Chen, L Ma, P Xu, ... Science Advances 7 (40), eabg1850, 2021 | 95 | 2021 |
A novel acidic matrix protein, PfN44, stabilizes magnesium calcite to inhibit the crystallization of aragonite C Pan, D Fang, G Xu, J Liang, G Zhang, H Wang, L Xie, R Zhang Journal of Biological Chemistry 289 (5), 2776-2787, 2014 | 83 | 2014 |
Novel basic protein, PfN23, functions as key macromolecule during nacre formation D Fang, C Pan, H Lin, Y Lin, G Zhang, H Wang, M He, L Xie, R Zhang Journal of Biological Chemistry 287 (19), 15776-15785, 2012 | 73 | 2012 |
Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3. 3K27M mutation R Tatavosian, HN Duc, TN Huynh, D Fang, B Schmitt, X Shi, Y Deng, ... Nature communications 9 (1), 2080, 2018 | 71 | 2018 |
A lesson learned from the H3. 3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo? KM Chan, J Han, D Fang, H Gan, Z Zhang Cell cycle 12 (16), 2546-2552, 2013 | 65 | 2013 |
Joint single-cell multiomic analysis in Wnt3a induced asymmetric stem cell division Z Sun, Y Tang, Y Zhang, Y Fang, J Jia, W Zeng, D Fang Nature Communications 12 (1), 5941, 2021 | 41 | 2021 |
SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters Y Zhang, Y Fang, Y Tang, S Han, J Jia, X Wan, J Chen, Y Yuan, B Zhao, ... Nature Communications 13 (1), 3190, 2022 | 34 | 2022 |
Histone mutations and cancer D Fang, J Han Springer Singapore, 2021 | 34 | 2021 |
The H3K36me2 methyltransferase NSD1 modulates H3K27ac at active enhancers to safeguard gene expression Y Fang, Y Tang, Y Zhang, Y Pan, J Jia, Z Sun, W Zeng, J Chen, Y Yuan, ... Nucleic Acids Research 49 (11), 6281-6295, 2021 | 33 | 2021 |
Manipulating cation-π interactions with genetically encoded tryptophan derivatives H Zhao, C Liu, W Ding, L Tang, Y Fang, Y Chen, L Hu, Y Yuan, D Fang, ... Journal of the American Chemical Society 144 (15), 6742-6748, 2022 | 28 | 2022 |
Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations Y Liu, Y Zhang, H Xue, M Cao, G Bai, Z Mu, Y Yao, S Sun, D Fang, ... Cell Discovery 7 (1), 32, 2021 | 25 | 2021 |
Ubiquitylation functions in the calcium carbonate biomineralization in the extracellular matrix D Fang, C Pan, H Lin, Y Lin, G Xu, G Zhang, H Wang, L Xie, R Zhang PLoS One 7 (4), e35715, 2012 | 19 | 2012 |