Ian J Groves
Ian J Groves
Associate Principal Investigator, Department of Medicine, University of Cambridge
Verified email at cam.ac.uk
Cited by
Cited by
Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter
DL Woodhall, IJ Groves, MB Reeves, G Wilkinson, JH Sinclair
Journal of Biological Chemistry 281 (49), 37652-37660, 2006
Pathogenesis of human papillomavirus‐associated mucosal disease
IJ Groves, N Coleman
The Journal of pathology 235 (4), 527-538, 2015
Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification
RE White, IJ Groves, E Turro, J Yee, E Kremmer, MJ Allday
PloS one 5 (11), e13979, 2010
Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic ‘pre-immediate-early’repression of viral gene expression mediated by histone post …
IJ Groves, MB Reeves, JH Sinclair
Journal of general virology 90 (10), 2364-2374, 2009
Identification of TRIM23 as a cofactor involved in the regulation of NF-κB by human cytomegalovirus
E Poole, I Groves, A Macdonald, Y Pang, A Alcami, J Sinclair
Journal of virology 83 (8), 3581-3590, 2009
LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels
MJ Murray, HK Saini, CA Siegler, JE Hanning, EM Barker, S van Dongen, ...
Cancer research 73 (15), 4872-4884, 2013
NF-κB-mediated activation of the chemokine CCL22 by the product of the human cytomegalovirus gene UL144 escapes regulation by viral IE86
E Poole, E Atkins, T Nakayama, O Yoshie, I Groves, A Alcami, J Sinclair
Journal of virology 82 (9), 4250-4256, 2008
CCCTC-binding factor recruitment to the early region of the human papillomavirus 18 genome regulates viral oncogene expression
C Paris, I Pentland, I Groves, DC Roberts, SJ Powis, N Coleman, ...
Journal of virology 89 (9), 4770-4785, 2015
Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state
JE Hanning, HK Saini, MJ Murray, MM Caffarel, S van Dongen, D Ward, ...
The Journal of pathology 231 (3), 354-366, 2013
Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription
I Pentland, K Campos-León, M Cotic, KJ Davies, CD Wood, IJ Groves, ...
PLoS biology 16 (10), e2005752, 2018
Knockdown of hDaxx in normally non-permissive undifferentiated cells does not permit human cytomegalovirus immediate-early gene expression
IJ Groves, JH Sinclair
Journal of general virology 88 (11), 2935-2940, 2007
Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes
CG Scarpini, IJ Groves, MR Pett, D Ward, N Coleman
The Journal of pathology 233 (3), 281-293, 2014
Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome
A Szymula, RD Palermo, A Bayoumy, IJ Groves, M Ba Abdullah, B Holder, ...
PLoS pathogens 14 (2), e1006890, 2018
HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome
IJ Groves, ELA Knight, QY Ang, CG Scarpini, N Coleman
Oncogene 35 (36), 4773-4786, 2016
Human papillomavirus genome integration in squamous carcinogenesis: what have next‐generation sequencing studies taught us?
IJ Groves, N Coleman
The Journal of pathology 245 (1), 9-18, 2018
Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells
SP Smith, CG Scarpini, IJ Groves, RI Odle, N Coleman
Scientific reports 6 (1), 1-10, 2016
Depletion of polycistronic transcripts using short interfering RNAs: cDNA synthesis method affects levels of non-targeted genes determined by quantitative PCR
JE Hanning, IJ Groves, MR Pett, N Coleman
Virology journal 10 (1), 1-5, 2013
Bromodomain inhibitors as therapeutics for herpesvirus-related disease: All BETs are off?
IJ Groves, JH Sinclair, MR Wills
Frontiers in Cellular and Infection Microbiology 10, 329, 2020
Human cytomegalovirus major immediate early transcripts arise predominantly from the canonical major immediate early promoter in reactivating progenitor-derived dendritic cells
R Mason, IJ Groves, MR Wills, JH Sinclair, MB Reeves
The Journal of general virology 101 (6), 635, 2020
Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention
IJ Groves, SE Jackson, EL Poole, A Nachshon, B Rozman, M Schwartz, ...
Proceedings of the National Academy of Sciences 118 (9), 2021
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Articles 1–20