Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach SA Carr, SE Abbatiello, BL Ackermann, C Borchers, B Domon, ... Molecular & Cellular Proteomics 13 (3), 907-917, 2014 | 555 | 2014 |
Abacavir induces loading of novel self-peptides into HLA-B* 57: 01: an autoimmune model for HLA-associated drug hypersensitivity MA Norcross, S Luo, L Lu, MT Boyne, M Gomarteli, AD Rennels, ... AIDS 26 (11), F21-F29, 2012 | 272 | 2012 |
Precise characterization of human histones in the H2A gene family by top down mass spectrometry MT Boyne II, JJ Pesavento, CA Mizzen, NL Kelleher Journal of proteome research 5 (2), 248-253, 2006 | 175 | 2006 |
Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster GJ Gatto, MT Boyne, NL Kelleher, CT Walsh Journal of the American Chemical Society 128 (11), 3838-3847, 2006 | 160 | 2006 |
Top-down proteomics on a chromatographic time scale using linear ion trap Fourier transform hybrid mass spectrometers BA Parks, L Jiang, PM Thomas, CD Wenger, MJ Roth, MT Boyne, ... Analytical chemistry 79 (21), 7984-7991, 2007 | 152 | 2007 |
Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units YA Chan, MT Boyne II, AM Podevels, AK Klimowicz, J Handelsman, ... Proceedings of the National Academy of Sciences 103 (39), 14349-14354, 2006 | 151* | 2006 |
Precise and parallel characterization of coding polymorphisms, alternative splicing, and modifications in human proteins by mass spectrometry MJ Roth, AJ Forbes, MT Boyne, YB Kim, DE Robinson, NL Kelleher Molecular & Cellular Proteomics 4 (7), 1002-1008, 2005 | 122* | 2005 |
A retrospective evaluation of the use of mass spectrometry in FDA biologics license applications S Rogstad, A Faustino, A Ruth, D Keire, M Boyne, J Park Journal of the American Society for Mass Spectrometry 28 (5), 786-794, 2016 | 110 | 2016 |
TAK-101 nanoparticles induce gluten-specific tolerance in celiac disease: a randomized, double-blind, placebo-controlled study CP Kelly, JA Murray, DA Leffler, DR Getts, AC Bledsoe, G Smithson, ... Gastroenterology 161 (1), 66-80. e8, 2021 | 106 | 2021 |
Post-translational structural modifications of immunoglobulin G and their effect on biological activity LK Hmiel, KA Brorson, MT Boyne Analytical and bioanalytical chemistry 407, 79-94, 2015 | 88 | 2015 |
Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval MT Boyne, BA Garcia, M Li, L Zamdborg, CD Wenger, S Babai, ... Journal of proteome research 8 (1), 374-379, 2009 | 73 | 2009 |
“Proteotyping”: population proteomics of human leukocytes using top down mass spectrometry MJ Roth, BA Parks, JT Ferguson, MT Boyne, NL Kelleher Analytical chemistry 80 (8), 2857-2866, 2008 | 72 | 2008 |
The role of mass spectrometry in the characterization of biologic protein products D Rathore, A Faustino, J Schiel, E Pang, M Boyne, S Rogstad Expert review of proteomics 15 (5), 431-449, 2018 | 68 | 2018 |
Determination of the NISTmAb primary structure T Formolo, M Ly, M Levy, L Kilpatrick, S Lute, K Phinney, L Marzilli, ... State-of-the-art and emerging technologies for therapeutic monoclonal …, 2015 | 63 | 2015 |
Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry B Wang, AC Gucinski, DA Keire, LF Buhse, MT Boyne II Analyst 138 (10), 3058-3065, 2013 | 58 | 2013 |
Direct approach for qualitative and quantitative characterization of glycoproteins using tandem mass tags and an LTQ Orbitrap XL electron transfer dissociation hybrid mass … H Ye, MT Boyne, LF Buhse, J Hill Analytical chemistry 85 (3), 1531-1539, 2013 | 56 | 2013 |
Characterization of the aminocarboxycyclopropane-forming enzyme CmaC WL Kelly, MT Boyne, E Yeh, DA Vosburg, DP Galonić, NL Kelleher, ... Biochemistry 46 (2), 359-368, 2007 | 53 | 2007 |
Characterization of currently marketed heparin products: Analysis of heparin digests by RPIP-UHPLC–QTOF-MS B Wang, LF Buhse, A Al-Hakim, MTB Ii, DA Keire Journal of pharmaceutical and biomedical analysis 67, 42-50, 2012 | 46 | 2012 |
Bioreactor process parameter screening utilizing a Plackett-Burman design for a model monoclonal antibody CD Agarabi, JE Schiel, SC Lute, BK Chavez, MT Boyne II, KA Brorson, ... Journal of pharmaceutical sciences 104 (6), 1919-1928, 2015 | 45 | 2015 |
Quality assessment of US marketplace vancomycin for injection products using high-resolution liquid chromatography-mass spectrometry and potency assays ME Hadwiger, CD Sommers, DJ Mans, V Patel, MT Boyne Antimicrobial agents and chemotherapy 56 (6), 2824-2830, 2012 | 45 | 2012 |