| GLASS: a comprehensive database for experimentally-validated GPCR-ligand associations WKB Chan, H Zhang, J Yang, JR Brender, J Hur, A Özgür, Y Zhang Bioinformatics, btv302, 2015 | 53 | 2015 |
| Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons HQ Xie, D Liang, KW Leung, VP Chen, KY Zhu, WKB Chan, RCY Choi, ... Journal of Biological Chemistry 285 (15), 11537-11546, 2010 | 53 | 2010 |
| Imaging the Midcontinent Rift beneath Lake Superior using large aperture seismic data A Tréhu, P Morel‐à‐l'Huissier, R Meyer, Z Hajnal, J Karl, R Mereu, ... Geophysical Research Letters 18 (4), 625-628, 1991 | 39 | 1991 |
| The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization VP Chen, RCY Choi, WKB Chan, KW Leung, AJY Guo, GKL Chan, ... Journal of Biological Chemistry 286 (38), 32948-32961, 2011 | 34 | 2011 |
| The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated … VP Chen, HQ Xie, WKB Chan, KW Leung, GKL Chan, RCY Choi, S Bon, ... Journal of biological chemistry 285 (35), 27265-27278, 2010 | 29 | 2010 |
| PRiMA directs a restricted localization of tetrameric AChE at synapses HQ Xie, KW Leung, VP Chen, GKL Chan, SL Xu, AJY Guo, KY Zhu, ... Chemico-biological interactions 187 (1-3), 78-83, 2010 | 27 | 2010 |
| Molecular assembly and biosynthesis of acetylcholinesterase in brain and muscle: the roles of t-peptide, FHB domain, and N-linked glycosylation VP Chen, WKW Luk, WKB Chan, KW Leung, AJY Guo, GKL Chan, SL Xu, ... Frontiers in molecular neuroscience 4, 36, 2011 | 25 | 2011 |
| Ontological and bioinformatic analysis of anti-coronavirus drugs and their Implication for drug repurposing against COVID-19 Y Liu, WKB Chan, Z Wang, J Hur, J Xie, H Yu, Y He Preprints, 2020 | 20 | 2020 |
| WDL-RF: predicting bioactivities of ligand molecules acting with G protein-coupled receptors by combining weighted deep learning and random forest J Wu, Q Zhang, W Wu, T Pang, H Hu, WKB Chan, X Ke, Y Zhang Bioinformatics 34 (13), 2271-2282, 2018 | 13 | 2018 |
| N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase WKB Chan, VP Chen, WKW Luk, RCY Choi, KWK Tsim Neuroscience letters 523 (1), 71-75, 2012 | 5 | 2012 |
| Precise modelling and interpretation of bioactivities of ligands targeting G protein-coupled receptors J Wu, B Liu, WKB Chan, W Wu, T Pang, H Hu, S Yan, X Ke, Y Zhang Bioinformatics 35 (14), i324-i332, 2019 | 3 | 2019 |
| The assembly of PRiMA-linked acetylcholinesterase: glycosylation is required for enzymatic activity but not for oligomerization VP Chen, RCY Choi, WKB Chan, KW Leung, AJY Guo, GKL Chan, ... Journal of Biological Chemistry, jbc. M111. 261248, 2011 | 3 | 2011 |
| An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells VP Chen, HQ Xie, WKB Chan, KW Leung, RCY Choi, KWK Tsim Chemico-biological interactions 187 (1-3), 106-109, 2010 | 3 | 2010 |
| Virtual Screening of Human Class-A GPCRs Using Ligand Profiles Built on Multiple Ligand–Receptor Interactions WKB Chan, Y Zhang Journal of Molecular Biology 432 (17), 4872-4890, 2020 | 1 | 2020 |
| Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection YH Yingtong Liu, Junguk Hur, Wallace K. B. Chan, Zhigang Wang, Jiangan Xie ... Scientific Data 8 (16), 2021 | | 2021 |
| Docking-Based Composite Virtual Screen for the Prediction of Putative Viral Targets of SARS-CoV-2 through Drug Repurposing W Chan, K Olson, J Sexton, H Carlson, J Traynor BRITISH JOURNAL OF PHARMACOLOGY 178 (2), 392-393, 2021 | | 2021 |
| Cosolvent Molecular Dynamics Simulation‐Based Discovery of Potential Allosteric Sites on Regulator of G Protein Signaling 4 W Chan, H Carlson, J Traynor The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
| Homologous G Protein-Coupled Receptors Boost the Modeling and Interpretation of Bioactivities of Ligand Molecules J Wu, Y Sun, WKB Chan, Y Zhu, W Zhu, W Huang, H Hu, S Yan, T Pang, ... Journal of chemical information and modeling 60 (3), 1865-1875, 2020 | | 2020 |
| A Docking‐Based Virtual Screen for Bifunctional μ‐Opioid Agonist/δ‐Opioid Antagonist Compounds W Chan, Y Zhang, J Traynor The FASEB Journal 33 (S1), 670.4-670.4, 2019 | | 2019 |
| Development and Application of Virtual Screening Methods for G Protein-Coupled Receptors W Chan | | 2018 |
Gallant KL ChanDivision of Life Science and Center for Chinese Medicine, The Hong Kong University of Science andVerified email at ust.hk
