Wallace KB Chan
Title
Cited by
Cited by
Year
GLASS: a comprehensive database for experimentally-validated GPCR-ligand associations
WKB Chan, H Zhang, J Yang, JR Brender, J Hur, A Özgür, Y Zhang
Bioinformatics, btv302, 2015
532015
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
HQ Xie, D Liang, KW Leung, VP Chen, KY Zhu, WKB Chan, RCY Choi, ...
Journal of Biological Chemistry 285 (15), 11537-11546, 2010
532010
Imaging the Midcontinent Rift beneath Lake Superior using large aperture seismic data
A Tréhu, P Morel‐à‐l'Huissier, R Meyer, Z Hajnal, J Karl, R Mereu, ...
Geophysical Research Letters 18 (4), 625-628, 1991
391991
The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization
VP Chen, RCY Choi, WKB Chan, KW Leung, AJY Guo, GKL Chan, ...
Journal of Biological Chemistry 286 (38), 32948-32961, 2011
342011
The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated …
VP Chen, HQ Xie, WKB Chan, KW Leung, GKL Chan, RCY Choi, S Bon, ...
Journal of biological chemistry 285 (35), 27265-27278, 2010
292010
PRiMA directs a restricted localization of tetrameric AChE at synapses
HQ Xie, KW Leung, VP Chen, GKL Chan, SL Xu, AJY Guo, KY Zhu, ...
Chemico-biological interactions 187 (1-3), 78-83, 2010
272010
Molecular assembly and biosynthesis of acetylcholinesterase in brain and muscle: the roles of t-peptide, FHB domain, and N-linked glycosylation
VP Chen, WKW Luk, WKB Chan, KW Leung, AJY Guo, GKL Chan, SL Xu, ...
Frontiers in molecular neuroscience 4, 36, 2011
252011
Ontological and bioinformatic analysis of anti-coronavirus drugs and their Implication for drug repurposing against COVID-19
Y Liu, WKB Chan, Z Wang, J Hur, J Xie, H Yu, Y He
Preprints, 2020
202020
WDL-RF: predicting bioactivities of ligand molecules acting with G protein-coupled receptors by combining weighted deep learning and random forest
J Wu, Q Zhang, W Wu, T Pang, H Hu, WKB Chan, X Ke, Y Zhang
Bioinformatics 34 (13), 2271-2282, 2018
132018
N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase
WKB Chan, VP Chen, WKW Luk, RCY Choi, KWK Tsim
Neuroscience letters 523 (1), 71-75, 2012
52012
Precise modelling and interpretation of bioactivities of ligands targeting G protein-coupled receptors
J Wu, B Liu, WKB Chan, W Wu, T Pang, H Hu, S Yan, X Ke, Y Zhang
Bioinformatics 35 (14), i324-i332, 2019
32019
The assembly of PRiMA-linked acetylcholinesterase: glycosylation is required for enzymatic activity but not for oligomerization
VP Chen, RCY Choi, WKB Chan, KW Leung, AJY Guo, GKL Chan, ...
Journal of Biological Chemistry, jbc. M111. 261248, 2011
32011
An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells
VP Chen, HQ Xie, WKB Chan, KW Leung, RCY Choi, KWK Tsim
Chemico-biological interactions 187 (1-3), 106-109, 2010
32010
Virtual Screening of Human Class-A GPCRs Using Ligand Profiles Built on Multiple Ligand–Receptor Interactions
WKB Chan, Y Zhang
Journal of Molecular Biology 432 (17), 4872-4890, 2020
12020
Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection
YH Yingtong Liu, Junguk Hur, Wallace K. B. Chan, Zhigang Wang, Jiangan Xie ...
Scientific Data 8 (16), 2021
2021
Docking-Based Composite Virtual Screen for the Prediction of Putative Viral Targets of SARS-CoV-2 through Drug Repurposing
W Chan, K Olson, J Sexton, H Carlson, J Traynor
BRITISH JOURNAL OF PHARMACOLOGY 178 (2), 392-393, 2021
2021
Cosolvent Molecular Dynamics Simulation‐Based Discovery of Potential Allosteric Sites on Regulator of G Protein Signaling 4
W Chan, H Carlson, J Traynor
The FASEB Journal 34 (S1), 1-1, 2020
2020
Homologous G Protein-Coupled Receptors Boost the Modeling and Interpretation of Bioactivities of Ligand Molecules
J Wu, Y Sun, WKB Chan, Y Zhu, W Zhu, W Huang, H Hu, S Yan, T Pang, ...
Journal of chemical information and modeling 60 (3), 1865-1875, 2020
2020
A Docking‐Based Virtual Screen for Bifunctional μ‐Opioid Agonist/δ‐Opioid Antagonist Compounds
W Chan, Y Zhang, J Traynor
The FASEB Journal 33 (S1), 670.4-670.4, 2019
2019
Development and Application of Virtual Screening Methods for G Protein-Coupled Receptors
W Chan
2018
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Articles 1–20