Charles Brenner
Charles Brenner
Roy J. Carver Chair & Head of Biochemistry, University of Iowa
Verified email at - Homepage
TitleCited byYear
p53 activation by knockdown technologies
ME Robu, JD Larson, A Nasevicius, S Beiraghi, C Brenner, SA Farber, ...
PLoS genetics 3 (5), e78, 2007
NAD+ metabolism in health and disease
P Belenky, KL Bogan, C Brenner
Trends in biochemical sciences 32 (1), 12-19, 2007
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, ...
Cell 126 (3), 611-625, 2006
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
P Bieganowski, C Brenner
Cell 117 (4), 495-502, 2004
The nitrilase superfamily: classification, structure and function
HC Pace, C Brenner
Genome biology 2 (1), reviews0001. 1, 2001
Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition
KL Bogan, C Brenner
Annu. Rev. Nutr. 28, 115-130, 2008
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction
I Miyajima, M Nakafuku, N Nakayama, C Brenner, A Miyajima, K Kaibuchi, ...
Cell 50 (7), 1011-1019, 1987
Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases
C Brenner
Biochemistry 41 (29), 9003-9014, 2002
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
P Belenky, FG Racette, KL Bogan, JM McClure, JS Smith, C Brenner
Cell 129 (3), 473-484, 2007
Catalysis in the nitrilase superfamily
C Brenner
Current opinion in structural biology 12 (6), 775-782, 2002
Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease.
C Brenner, RS Fuller
Proceedings of the National Academy of Sciences 89 (3), 922-926, 1992
The ataxia–oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4
PM Clements, C Breslin, ED Deeks, PJ Byrd, L Ju, P Bieganowski, ...
DNA repair 3 (11), 1493-1502, 2004
Scaffolding Functions of Arrestin-2 Revealed by Crystal Structure and Mutagenesis,
SK Milano, HC Pace, YM Kim, C Brenner, JL Benovic
Biochemistry 41 (10), 3321-3328, 2002
Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit
HC Pace, PN Garrison, AK Robinson, LD Barnes, A Draganescu, ...
Proceedings of the National Academy of Sciences 95 (10), 5484-5489, 1998
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
SAJ Trammell, MS Schmidt, BJ Weidemann, P Redpath, F Jaksch, ...
Nature communications 7, 12948, 2016
Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants
CL Linster, TA Gomez, KC Christensen, LN Adler, BD Young, C Brenner, ...
Journal of Biological Chemistry 282 (26), 18879-18885, 2007
Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins
C Brenner, P Garrison, J Gilmour, D Peisach, D Ringe, GA Petsko, ...
Nature structural biology 4 (3), 231, 1997
The histidine triad superfamily of nucleotide‐binding proteins
C Brenner, P Bieganowski, HC Pace, K Huebner
Journal of cellular physiology 181 (2), 179-187, 1999
Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers
HC Pace, SC Hodawadekar, A Draganescu, J Huang, P Bieganowski, ...
Current biology 10 (15), 907-917, 2000
CDC33 encodes mRNA cap-binding protein eIF-4E of Saccharomyces cerevisiae.
C Brenner, N Nakayama, M Goebl, K Tanaka, A Toh-e, K Matsumoto
Molecular and cellular biology 8 (8), 3556-3559, 1988
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