The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune SuppressionMicrobiome Influences Pancreatic Oncogenesis S Pushalkar, M Hundeyin, D Daley, CP Zambirinis, E Kurz, A Mishra, ... Cancer discovery 8 (4), 403-416, 2018 | 983* | 2018 |
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL B Aykut, S Pushalkar, R Chen, Q Li, R Abengozar, JI Kim, SA Shadaloey, ... Nature 574 (7777), 264-267, 2019 | 593 | 2019 |
PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer B Diskin, S Adam, MF Cassini, G Sanchez, M Liria, B Aykut, C Buttar, E Li, ... Nature immunology 21 (4), 442-454, 2020 | 277 | 2020 |
NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma D Daley, VR Mani, N Mohan, N Akkad, GSDB Pandian, S Savadkar, ... Journal of Experimental Medicine 214 (6), 1711-1724, 2017 | 212 | 2017 |
RIP1 kinase drives macrophage-mediated adaptive immune tolerance in pancreatic cancer W Wang, JM Marinis, AM Beal, S Savadkar, Y Wu, M Khan, PS Taunk, ... Cancer cell 34 (5), 757-774. e7, 2018 | 189 | 2018 |
Gut microbial profile analysis by MiSeq sequencing of pancreatic carcinoma patients in China Z Ren, J Jiang, H Xie, A Li, H Lu, S Xu, L Zhou, H Zhang, G Cui, X Chen, ... Oncotarget 8 (56), 95176, 2017 | 177 | 2017 |
Short‐or long‐term high‐fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: An important role for CXCL1 B Chang, MJ Xu, Z Zhou, Y Cai, M Li, W Wang, D Feng, A Bertola, ... Hepatology 62 (4), 1070-1085, 2015 | 173 | 2015 |
SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling C Fedele, S Li, KW Teng, CJR Foster, D Peng, H Ran, P Mita, MJ Geer, ... Journal of Experimental Medicine 218 (1), e20201414, 2020 | 162 | 2020 |
The neutrophil lymphocyte ratio is associated with breast cancer prognosis: an updated systematic review and meta-analysis B Wei, M Yao, C Xing, W Wang, J Yao, Y Hong, Y Liu, P Fu OncoTargets and therapy 9, 5567–5575, 2016 | 149 | 2016 |
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis P Mukhopadhyay, B Horváth, M Rajesh, ZV Varga, K Gariani, D Ryu, ... Journal of hepatology 66 (3), 589-600, 2017 | 148 | 2017 |
In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma F Li, Q Huang, TA Luster, H Hu, H Zhang, WL Ng, A Khodadadi-Jamayran, ... Cancer discovery 10 (2), 270-287, 2020 | 142 | 2020 |
Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment D Barkley, R Moncada, M Pour, DA Liberman, I Dryg, G Werba, W Wang, ... Nature genetics 54 (8), 1192-1201, 2022 | 139 | 2022 |
Neutrophil–hepatic stellate cell interactions promote fibrosis in experimental steatohepatitis Z Zhou, MJ Xu, Y Cai, W Wang, JX Jiang, ZV Varga, D Feng, P Pacher, ... Cellular and molecular gastroenterology and hepatology 5 (3), 399-413, 2018 | 130 | 2018 |
Mitochondrial DNA–enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity Y Cai, MJ Xu, EH Koritzinsky, Z Zhou, W Wang, H Cao, PST Yuen, ... JCI insight 2 (14), 2017 | 86 | 2017 |
Targeting Piezo1 unleashes innate immunity against cancer and infectious disease B Aykut, R Chen, JI Kim, D Wu, SAA Shadaloey, R Abengozar, P Preiss, ... Science Immunology 25 (50), 75, 2020 | 82 | 2020 |
Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma RM Barilla, B Diskin, RC Caso, KB Lee, N Mohan, C Buttar, S Adam, ... Nature communications 10 (1), 1424, 2019 | 71 | 2019 |
Recipient outcomes of salvage liver transplantation versus primary liver transplantation: A systematic review and meta‐analysis Z Hu, W Wang, Z Li, S Ye, SS Zheng Liver Transplantation 18 (11), 1316-1323, 2012 | 70 | 2012 |
Identification of a RIP1 kinase inhibitor clinical candidate (GSK3145095) for the treatment of pancreatic cancer PA Harris, JM Marinis, JD Lich, SB Berger, A Chirala, JA Cox, PM Eidam, ... ACS medicinal chemistry letters 10 (6), 857-862, 2019 | 65 | 2019 |
Inflammation is independent of steatosis in a murine model of steatohepatitis W Wang, MJ Xu, Y Cai, Z Zhou, H Cao, P Mukhopadhyay, P Pacher, ... Hepatology 66 (1), 108-123, 2017 | 65 | 2017 |
Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids Y Gao, Z Zhou, T Ren, SJ Kim, Y He, W Seo, A Guillot, Y Ding, R Wu, ... Gut 68 (7), 1311-1322, 2019 | 52 | 2019 |