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Jeremy D. Waight
Jeremy D. Waight
Verified email at gsk.com
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Year
Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature
KM Kokolus, ML Capitano, CT Lee, JWL Eng, JD Waight, BL Hylander, ...
Proceedings of the National Academy of Sciences 110 (50), 20176-20181, 2013
3242013
Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis
JD Waight, C Netherby, ML Hensen, A Miller, Q Hu, S Liu, PN Bogner, ...
The Journal of clinical investigation 123 (10), 4464-4478, 2013
3232013
Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism
JD Waight, Q Hu, A Miller, S Liu, SI Abrams
PloS one 6 (11), e27690, 2011
2722011
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens
JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ...
Cancer Cell 33 (6), 1033-1047. e5, 2018
802018
Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans
JD Waight, S Takai, B Marelli, G Qin, KW Hance, D Zhang, R Tighe, Y Lan, ...
The Journal of Immunology 194 (3), 878-882, 2015
782015
Identification of a G-CSF-Granulocytic MDSC axis that promotes tumor progression
SI Abrams, JD Waight
Oncoimmunology 1 (4), 550-551, 2012
562012
Regulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic …
JD Waight, D Banik, EA Griffiths, MJ Nemeth, SI Abrams
Journal of Biological Chemistry 289 (22), 15642-15652, 2014
402014
Harnessing co-stimulatory TNF receptors for cancer immunotherapy: current approaches and future opportunities
JD Waight, RB Gombos, NS Wilson
Human Antibodies 25 (3-4), 87-109, 2017
262017
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody
RB Gombos, A Gonzalez, M Manrique, D Chand, D Savitsky, B Morin, ...
PLoS One 13 (4), e0191926, 2018
212018
Anti-OX40 antibodies
M Van Dijk, EV Breous-Nystrom, G Ritter, D Schaer, ...
US Patent 10,259,882, 2019
202019
Emergence of the CD226 axis in cancer immunotherapy
M Conner, KW Hance, S Yadavilli, J Smothers, JD Waight
Frontiers in Immunology 13, 914406, 2022
192022
INCAGN02390, a novel antagonist antibody that targets the co-inhibitory receptor TIM-3
J Waight, P Iyer, E Breous-Nystrom, C Riordan, M Findeis, D Underwood, ...
Cancer Res 78 (13 Supplement), 3825-25, 2018
182018
A novel agonist antibody (INCAGN01876) that targets the costimulatory receptor GITR
AM Gonzalez, E Breous, ML Manrique, D Savitsky, J Waight, R Gombos, ...
Cancer Research 76 (14_Supplement), 3220-3220, 2016
122016
Antibodies and methods of use thereof
NS Wilson, JD Waight, G Ritter, D Schaer, D Hirschhorn-Cymerman, ...
US Patent 11,447,557, 2022
112022
Immunodynamics of explanted human tumors for immuno‐oncology
A Dubuisson, JE Fahrner, AG Goubet, S Terrisse, N Voisin, C Bayard, ...
EMBO Molecular Medicine 13 (1), e12850, 2021
102021
INCAGN1876, a unique GITR agonist antibody that facilitates GITR oligomerization
AM Gonzalez, M Manrique, L Swiech, T Horn, J Waight, Y Liu, S Lin, ...
American Association for Cancer Research Annual Meeting, 2017
82017
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
JD Worboys, KN Vowell, RK Hare, AR Ambrose, M Bertuzzi, MA Conner, ...
Nature Communications 14 (1), 5016, 2023
62023
Anti-OX40 antibodies and anti-GITR antibodies
NS Wilson, JD Waight, DJ Underwood, EV Breous-Nystrom, G Ritter, ...
US Patent 11,359,028, 2022
62022
Anti-OX40 antibodies
M Van Dijk, EV Breous-Nystrom, V Seibert, G Ritter, D Schaer, ...
US Patent 11,136,404, 2021
62021
Antibodies and methods of use thereof
NS Wilson, JD Waight, G Ritter, D Schaer, D Hirschhorn-Cymerman, ...
US Patent 10,836,830, 2020
62020
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