Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature KM Kokolus, ML Capitano, CT Lee, JWL Eng, JD Waight, BL Hylander, ... Proceedings of the National Academy of Sciences 110 (50), 20176-20181, 2013 | 324 | 2013 |
Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis JD Waight, C Netherby, ML Hensen, A Miller, Q Hu, S Liu, PN Bogner, ... The Journal of clinical investigation 123 (10), 4464-4478, 2013 | 323 | 2013 |
Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism JD Waight, Q Hu, A Miller, S Liu, SI Abrams PloS one 6 (11), e27690, 2011 | 272 | 2011 |
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ... Cancer Cell 33 (6), 1033-1047. e5, 2018 | 80 | 2018 |
Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans JD Waight, S Takai, B Marelli, G Qin, KW Hance, D Zhang, R Tighe, Y Lan, ... The Journal of Immunology 194 (3), 878-882, 2015 | 78 | 2015 |
Identification of a G-CSF-Granulocytic MDSC axis that promotes tumor progression SI Abrams, JD Waight Oncoimmunology 1 (4), 550-551, 2012 | 56 | 2012 |
Regulation of the interferon regulatory factor-8 (IRF-8) tumor suppressor gene by the signal transducer and activator of transcription 5 (STAT5) transcription factor in chronic … JD Waight, D Banik, EA Griffiths, MJ Nemeth, SI Abrams Journal of Biological Chemistry 289 (22), 15642-15652, 2014 | 40 | 2014 |
Harnessing co-stimulatory TNF receptors for cancer immunotherapy: current approaches and future opportunities JD Waight, RB Gombos, NS Wilson Human Antibodies 25 (3-4), 87-109, 2017 | 26 | 2017 |
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody RB Gombos, A Gonzalez, M Manrique, D Chand, D Savitsky, B Morin, ... PLoS One 13 (4), e0191926, 2018 | 21 | 2018 |
Anti-OX40 antibodies M Van Dijk, EV Breous-Nystrom, G Ritter, D Schaer, ... US Patent 10,259,882, 2019 | 20 | 2019 |
Emergence of the CD226 axis in cancer immunotherapy M Conner, KW Hance, S Yadavilli, J Smothers, JD Waight Frontiers in Immunology 13, 914406, 2022 | 19 | 2022 |
INCAGN02390, a novel antagonist antibody that targets the co-inhibitory receptor TIM-3 J Waight, P Iyer, E Breous-Nystrom, C Riordan, M Findeis, D Underwood, ... Cancer Res 78 (13 Supplement), 3825-25, 2018 | 18 | 2018 |
A novel agonist antibody (INCAGN01876) that targets the costimulatory receptor GITR AM Gonzalez, E Breous, ML Manrique, D Savitsky, J Waight, R Gombos, ... Cancer Research 76 (14_Supplement), 3220-3220, 2016 | 12 | 2016 |
Antibodies and methods of use thereof NS Wilson, JD Waight, G Ritter, D Schaer, D Hirschhorn-Cymerman, ... US Patent 11,447,557, 2022 | 11 | 2022 |
Immunodynamics of explanted human tumors for immuno‐oncology A Dubuisson, JE Fahrner, AG Goubet, S Terrisse, N Voisin, C Bayard, ... EMBO Molecular Medicine 13 (1), e12850, 2021 | 10 | 2021 |
INCAGN1876, a unique GITR agonist antibody that facilitates GITR oligomerization AM Gonzalez, M Manrique, L Swiech, T Horn, J Waight, Y Liu, S Lin, ... American Association for Cancer Research Annual Meeting, 2017 | 8 | 2017 |
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation JD Worboys, KN Vowell, RK Hare, AR Ambrose, M Bertuzzi, MA Conner, ... Nature Communications 14 (1), 5016, 2023 | 6 | 2023 |
Anti-OX40 antibodies and anti-GITR antibodies NS Wilson, JD Waight, DJ Underwood, EV Breous-Nystrom, G Ritter, ... US Patent 11,359,028, 2022 | 6 | 2022 |
Anti-OX40 antibodies M Van Dijk, EV Breous-Nystrom, V Seibert, G Ritter, D Schaer, ... US Patent 11,136,404, 2021 | 6 | 2021 |
Antibodies and methods of use thereof NS Wilson, JD Waight, G Ritter, D Schaer, D Hirschhorn-Cymerman, ... US Patent 10,836,830, 2020 | 6 | 2020 |